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Murcko scaffold

Ring system with 4 rings and 22 atoms

36 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
36
With full pages
4
Scaffold SMILES

O=C(OCC1c2ccccc2-c2ccccc21)N1CCSC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1CCSC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

(-)-(R)-Fmoc-4-thiazolidinecarboxylic acid chemical structure, C19H17NO4S, CAS 133054-21-4
(-)-(R)-Fmoc-4-thiazolidinecarboxylic acid
CAS 133054-21-4C19H17NO4S
(R)-3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-5,5-dimethylthiazolidine-4-carboxylic acid chemical structure, C21H21NO4S, CAS 753030-79-4
(R)-3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-5,5-dimethylthiazolidine-4-carboxylic acid
CAS 753030-79-4C21H21NO4S
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid chemical structure, C21H21NO4S, CAS 1822471-05-5
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
CAS 1822471-05-5C21H21NO4S
3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,3-thiazolidine-2-carboxylic acid chemical structure, C19H17NO4S, CAS 1043933-69-2
3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,3-thiazolidine-2-carboxylic acid
CAS 1043933-69-2C19H17NO4S
(S)-3-(((9H-Fluoren-9-yl)methoxy)carbonyl)thiazolidine-4-carboxylic acid chemical structure, C19H17NO4S, CAS 198545-89-0
(S)-3-(((9H-Fluoren-9-yl)methoxy)carbonyl)thiazolidine-4-carboxylic acid
CAS 198545-89-0C19H17NO4S
(S)-Fmoc-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid chemical structure, C21H21NO4S, CAS 141636-66-0
(S)-Fmoc-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
CAS 141636-66-0C21H21NO4S
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2,2,5,5-tetramethyl-1,3-thiazolidine-4-carboxylic acid chemical structure, C23H25NO4S, CAS 2137457-49-7
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2,2,5,5-tetramethyl-1,3-thiazolidine-4-carboxylic acid
CAS 2137457-49-7C23H25NO4S
Fmoc-(R)-thiazolidine-2-carboxylic acid chemical structure, C19H17NO4S, CAS 1217481-34-9
Fmoc-(R)-thiazolidine-2-carboxylic acid
CAS 1217481-34-9C19H17NO4S
(4S)-3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2-methylthiazolidine-4-carboxylic acid chemical structure, C20H19NO4S, CAS 1217544-28-9
(4S)-3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2-methylthiazolidine-4-carboxylic acid
CAS 1217544-28-9C20H19NO4S
(R)-3-((9H-Fluoren-9-ylmethoxy)carbonyl)-2,2-dimethylthiazolidine-4-carboxylic Acid chemical structure, C21H21NO4S, CAS 873842-06-9
(R)-3-((9H-Fluoren-9-ylmethoxy)carbonyl)-2,2-dimethylthiazolidine-4-carboxylic Acid
CAS 873842-06-9C21H21NO4S
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-methyl-1,3-thiazolidine-4-carboxylic acid chemical structure, C20H19NO4S, CAS 1339682-10-8
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-methyl-1,3-thiazolidine-4-carboxylic acid
CAS 1339682-10-8C20H19NO4S
3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2-ethylthiazolidine-4-carboxylic acid chemical structure, C21H21NO4S, CAS 1339917-80-4
3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2-ethylthiazolidine-4-carboxylic acid
CAS 1339917-80-4C21H21NO4S
Fmoc-(4-s)-2,2-dimethyl-1,3-thiazolidine-4-carboxylic acid chemical structure, C21H21NO4S, CAS 1932198-36-1
Fmoc-(4-s)-2,2-dimethyl-1,3-thiazolidine-4-carboxylic acid
CAS 1932198-36-1C21H21NO4S
3-(9H-Fluoren-9-ylmethyl) 4-methyl (4R)-1,3-thiazolidine-3,4-dicarboxylate chemical structure, C20H19NO4S, CAS 1820571-72-9
3-(9H-Fluoren-9-ylmethyl) 4-methyl (4R)-1,3-thiazolidine-3,4-dicarboxylate
CAS 1820571-72-9C20H19NO4S
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2,2-dimethyl-1,3-thiazolidine-4-carboxylic acid chemical structure, C21H21NO4S, CAS 1822491-51-9
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2,2-dimethyl-1,3-thiazolidine-4-carboxylic acid
CAS 1822491-51-9C21H21NO4S
Fmoc-(S)-thiazolidine-2-carboxylic acid chemical structure, C19H17NO4S, CAS 1366384-03-3
Fmoc-(S)-thiazolidine-2-carboxylic acid
CAS 1366384-03-3C19H17NO4S
(2S,4R)-3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-(trifluoromethyl)-1,3-thiazolidine-4-carboxylic acid chemical structure, C20H16F3NO4S, CAS 2137026-79-8
(2S,4R)-3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-(trifluoromethyl)-1,3-thiazolidine-4-carboxylic acid
CAS 2137026-79-8C20H16F3NO4S
2-(3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,3-thiazolidin-4-yl)acetic acid chemical structure, C20H19NO4S, CAS 2137661-43-7
2-(3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,3-thiazolidin-4-yl)acetic acid
CAS 2137661-43-7C20H19NO4S
2-[(2S)-3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-(trifluoromethyl)-1,3-thiazolidin-4-yl]acetic acid chemical structure, C21H18F3NO4S, CAS 2137422-08-1
2-[(2S)-3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-(trifluoromethyl)-1,3-thiazolidin-4-yl]acetic acid
CAS 2137422-08-1C21H18F3NO4S
2-(3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-pentyl-1,3-thiazolidin-4-yl)acetic acid chemical structure, C25H29NO4S, CAS 2138227-90-2
2-(3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-pentyl-1,3-thiazolidin-4-yl)acetic acid
CAS 2138227-90-2C25H29NO4S
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-pentyl-1,3-thiazolidine-4-carboxylic acid chemical structure, C24H27NO4S, CAS 2137478-35-2
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-pentyl-1,3-thiazolidine-4-carboxylic acid
CAS 2137478-35-2C24H27NO4S
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-[2-(methylsulfanyl)ethyl]-1,3-thiazolidine-4-carboxylic acid chemical structure, C22H23NO4S2, CAS 2137493-98-0
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-[2-(methylsulfanyl)ethyl]-1,3-thiazolidine-4-carboxylic acid
CAS 2137493-98-0C22H23NO4S2
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-(2-methylpropyl)-1,3-thiazolidine-4-carboxylic acid chemical structure, C23H25NO4S, CAS 2137484-18-3
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-(2-methylpropyl)-1,3-thiazolidine-4-carboxylic acid
CAS 2137484-18-3C23H25NO4S
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-(trifluoromethyl)-1,3-thiazolidine-4-carboxylic acid chemical structure, C20H16F3NO4S, CAS 2171645-75-1
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-(trifluoromethyl)-1,3-thiazolidine-4-carboxylic acid
CAS 2171645-75-1C20H16F3NO4S