CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 18 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
8
With full pages
3
Scaffold SMILES

C=C1CCC(c2cccc3ccccc23)C(=O)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C=C1CCC(c2cccc3ccccc23)C(=O)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

2H-Pyran-2-one, 6-(bromomethylene)tetrahydro-3-(1-naphthalenyl)- chemical structure, C16H13BrO2, CAS 144298-62-4
2H-Pyran-2-one, 6-(bromomethylene)tetrahydro-3-(1-naphthalenyl)-
CAS 144298-62-4C16H13BrO2
Bromoenol lactone chemical structure, C16H13BrO2, CAS 88070-98-8
Bromoenol lactone
CAS 88070-98-8C16H13BrO2
(6E)-6-(Iodomethylidene)-3-(naphthalen-1-yl)oxan-2-one chemical structure, C16H13IO2, CAS 88070-99-9
(6E)-6-(Iodomethylidene)-3-(naphthalen-1-yl)oxan-2-one
CAS 88070-99-9C16H13IO2
(S)-Bromoenol lactone chemical structure, C16H13BrO2, CAS 478288-94-7
(S)-Bromoenol lactone
CAS 478288-94-7C16H13BrO2
(R)-Bromoenol lactone chemical structure, C16H13BrO2, CAS 478288-90-3
(R)-Bromoenol lactone
CAS 478288-90-3C16H13BrO2
(3R,6Z)-6-(Iodomethylidene)-3-(naphthalen-1-yl)oxan-2-one chemical structure, C16H13IO2, CAS 138752-91-7
(3R,6Z)-6-(Iodomethylidene)-3-(naphthalen-1-yl)oxan-2-one
CAS 138752-91-7C16H13IO2
(3R)-6-(Iodomethylidene)-3-naphthalen-1-yloxan-2-one chemical structure, C16H13IO2
(3R)-6-(Iodomethylidene)-3-naphthalen-1-yloxan-2-one
C16H13IO2
(R)-6-(Iodomethylene)-3-(naphthalen-1-yl)tetrahydro-2H-pyran-2-one chemical structure, C16H13IO2
(R)-6-(Iodomethylene)-3-(naphthalen-1-yl)tetrahydro-2H-pyran-2-one
C16H13IO2