CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 22 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
6
With full pages
4
Scaffold SMILES

O=C(NCc1cccs1)c1c[nH]c2nc3ccccc3nc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1cccs1)c1c[nH]c2nc3ccccc3nc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

2-Amino-1-(2-methoxyethyl)-N-(thiophen-2-ylmethyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide chemical structure, C19H19N5O2S, CAS 840518-72-1
2-Amino-1-(2-methoxyethyl)-N-(thiophen-2-ylmethyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide
CAS 840518-72-1C19H19N5O2S
2-Amino-1-(2-methylpropyl)-N-[(thiophen-2-yl)methyl]-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C20H21N5OS, CAS 842955-30-0
2-Amino-1-(2-methylpropyl)-N-[(thiophen-2-yl)methyl]-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 842955-30-0C20H21N5OS
2-Amino-1-pentyl-N-(thiophen-2-ylmethyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide chemical structure, C21H23N5OS, CAS 573944-97-5
2-Amino-1-pentyl-N-(thiophen-2-ylmethyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide
CAS 573944-97-5C21H23N5OS
2-Amino-1-butyl-N-(thiophen-2-ylmethyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide chemical structure, C20H21N5OS, CAS 840514-69-4
2-Amino-1-butyl-N-(thiophen-2-ylmethyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide
CAS 840514-69-4C20H21N5OS
2-Amino-1-(3-methoxypropyl)-N-(thiophen-2-ylmethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C20H21N5O2S, CAS 843629-47-0
2-Amino-1-(3-methoxypropyl)-N-(thiophen-2-ylmethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 843629-47-0C20H21N5O2S
1,2-Diamino-N-(thiophen-2-ylmethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C16H14N6OS, CAS 881551-38-8
1,2-Diamino-N-(thiophen-2-ylmethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 881551-38-8C16H14N6OS