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Murcko scaffold

Ring system with 2 rings and 16 atoms

12 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
12
With full pages
3
Scaffold SMILES

O=c1cc(C=Cc2ccccc2)[nH]c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc(C=Cc2ccccc2)[nH]c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

6-[(E)-2-(4-Methoxyphenyl)ethenyl]-1,3-dimethyl-5-nitropyrimidine-2,4-dione chemical structure, C15H15N3O5, CAS 741-86-6
6-[(E)-2-(4-Methoxyphenyl)ethenyl]-1,3-dimethyl-5-nitropyrimidine-2,4-dione
CAS 741-86-6C15H15N3O5
S.pombe lumazine synthase-IN-1 chemical structure, C14H13N3O6, CAS 331726-35-3
S.pombe lumazine synthase-IN-1
CAS 331726-35-3C14H13N3O6
5-Nitro-6-styryl-pyrimidine-2,4-diol chemical structure, C12H9N3O4, CAS 16290-66-7
5-Nitro-6-styryl-pyrimidine-2,4-diol
CAS 16290-66-7C12H9N3O4
1,3-Dimethyl-5-nitro-6-[(E)-2-(2,3,4-trimethoxyphenyl)ethenyl]pyrimidine-2,4-dione chemical structure, C17H19N3O7, CAS 429653-34-9
1,3-Dimethyl-5-nitro-6-[(E)-2-(2,3,4-trimethoxyphenyl)ethenyl]pyrimidine-2,4-dione
CAS 429653-34-9C17H19N3O7
6-[(E)-2-[4-(Diethylamino)-3-nitrophenyl]ethenyl]-5-nitro-1H-pyrimidine-2,4-dione chemical structure, C16H17N5O6, CAS 381708-67-4
6-[(E)-2-[4-(Diethylamino)-3-nitrophenyl]ethenyl]-5-nitro-1H-pyrimidine-2,4-dione
CAS 381708-67-4C16H17N5O6
6-[(E)-2-(4-tert-Butylphenyl)ethenyl]-5-nitro-1H-pyrimidine-2,4-dione chemical structure, C16H17N3O4, CAS 666712-59-0
6-[(E)-2-(4-tert-Butylphenyl)ethenyl]-5-nitro-1H-pyrimidine-2,4-dione
CAS 666712-59-0C16H17N3O4
6-[(E)-2-(5-Bromo-2-prop-2-enoxyphenyl)ethenyl]-5-nitro-1H-pyrimidine-2,4-dione chemical structure, C15H12BrN3O5, CAS 666712-57-8
6-[(E)-2-(5-Bromo-2-prop-2-enoxyphenyl)ethenyl]-5-nitro-1H-pyrimidine-2,4-dione
CAS 666712-57-8C15H12BrN3O5
6-[(E)-2-(2-Methylphenyl)ethenyl]-5-nitropyrimidine-2,4-diol chemical structure, C13H11N3O4, CAS 675856-15-2
6-[(E)-2-(2-Methylphenyl)ethenyl]-5-nitropyrimidine-2,4-diol
CAS 675856-15-2C13H11N3O4
5-Nitro-6-{(E)-2-[3-(prop-2-en-1-yloxy)phenyl]ethenyl}pyrimidine-2,4-diol chemical structure, C15H13N3O5, CAS 675856-02-7
5-Nitro-6-{(E)-2-[3-(prop-2-en-1-yloxy)phenyl]ethenyl}pyrimidine-2,4-diol
CAS 675856-02-7C15H13N3O5
2,4(1H,3H)-Pyrimidinedione, 1-((2-hydroxyethoxy)methyl)-5-methyl-6-((1Z)-2-phenylethenyl)- chemical structure, C16H18N2O4, CAS 131194-19-9
2,4(1H,3H)-Pyrimidinedione, 1-((2-hydroxyethoxy)methyl)-5-methyl-6-((1Z)-2-phenylethenyl)-
CAS 131194-19-9C16H18N2O4
{2-[(E)-2-(2,6-Dihydroxy-5-nitropyrimidin-4-yl)ethenyl]-6-ethoxyphenoxy}acetic acid chemical structure, C16H15N3O8, CAS 765925-93-7
{2-[(E)-2-(2,6-Dihydroxy-5-nitropyrimidin-4-yl)ethenyl]-6-ethoxyphenoxy}acetic acid
CAS 765925-93-7C16H15N3O8
2-[2-(2,6-Dioxo-1,2,3,6-tetrahydro-pyrimidin-4-yl)-vinyl]-6-methoxy-benzoic acid methyl ester chemical structure, C15H14N2O5, CAS 365542-66-1
2-[2-(2,6-Dioxo-1,2,3,6-tetrahydro-pyrimidin-4-yl)-vinyl]-6-methoxy-benzoic acid methyl ester
CAS 365542-66-1C15H14N2O5