Murcko scaffold

Ring system with 4 rings and 22 atoms

7 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 22
Chemicals: 7
With full pages: 6

Scaffold SMILES

O=C1CCc2cc(S(=O)(=O)N3CCCCC3)cc3c2N1CC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C1CCc2cc(S(=O)(=O)N3CCCCC3)cc3c2N1CC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

$Ethyl 1-({11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}sulfonyl)piperidine-4-carboxylate chemical structure, C19H24N2O5S, CAS 903358-91-8$

Ethyl 1-({11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}sulfonyl)piperidine-4-carboxylate

CAS 903358-91-8C₁₉H₂₄N₂O₅S

$Methyl 1-({11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}sulfonyl)piperidine-4-carboxylate chemical structure, C18H22N2O5S, CAS 898419-59-5$

Methyl 1-({11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}sulfonyl)piperidine-4-carboxylate

CAS 898419-59-5C₁₈H₂₂N₂O₅S

$6-[(4-Methylpiperidin-1-yl)sulfonyl]-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-11-one chemical structure, C17H22N2O3S, CAS 898419-76-6$

6-[(4-Methylpiperidin-1-yl)sulfonyl]-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-11-one

CAS 898419-76-6C₁₇H₂₂N₂O₃S

$1-({11-Oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}sulfonyl)piperidine-4-carboxamide chemical structure, C17H21N3O4S, CAS 898436-50-5$

1-({11-Oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}sulfonyl)piperidine-4-carboxamide

CAS 898436-50-5C₁₇H₂₁N₃O₄S

$6-[(3,5-Dimethylpiperidin-1-yl)sulfonyl]-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-11-one chemical structure, C18H24N2O3S, CAS 898462-72-1$

6-[(3,5-Dimethylpiperidin-1-yl)sulfonyl]-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-11-one

CAS 898462-72-1C₁₈H₂₄N₂O₃S

$6-[(3-Methylpiperidin-1-yl)sulfonyl]-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-11-one chemical structure, C17H22N2O3S, CAS 898436-27-6$

6-[(3-Methylpiperidin-1-yl)sulfonyl]-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-11-one

CAS 898436-27-6C₁₇H₂₂N₂O₃S

$Ethyl 1-({11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}sulfonyl)piperidine-3-carboxylate chemical structure, C19H24N2O5S, CAS 898419-80-2$

Ethyl 1-({11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-6-yl}sulfonyl)piperidine-3-carboxylate

CAS 898419-80-2C₁₉H₂₄N₂O₅S

Ring system with 4 rings and 22 atoms

Chemicals with this scaffold

Related scaffolds