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Murcko scaffold

Ring system with 3 rings and 12 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
12
Chemicals
9
With full pages
1
Scaffold SMILES

c1ccc(C2C3CNCC32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C2C3CNCC32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

6-(2-Methylphenyl)-3-azabicyclo[3.1.0]hexane chemical structure, C12H15N, CAS 1378833-22-7
6-(2-Methylphenyl)-3-azabicyclo[3.1.0]hexane
CAS 1378833-22-7C12H15N
6-(4-Fluorophenyl)-6-methyl-3-azabicyclo[3.1.0]hexane chemical structure, C12H14FN, CAS 1378796-73-6
6-(4-Fluorophenyl)-6-methyl-3-azabicyclo[3.1.0]hexane
CAS 1378796-73-6C12H14FN
6-(2-Methylphenyl)-3-azabicyclo[3.1.0]hexane hydrochloride chemical structure, C12H16ClN, CAS 2137654-93-2
6-(2-Methylphenyl)-3-azabicyclo[3.1.0]hexane hydrochloride
CAS 2137654-93-2C12H16ClN
6-(3-Chlorophenyl)-3-azabicyclo[3.1.0]hexane-6-carboxylic acid chemical structure, C12H12ClNO2, CAS 1369139-07-0
6-(3-Chlorophenyl)-3-azabicyclo[3.1.0]hexane-6-carboxylic acid
CAS 1369139-07-0C12H12ClNO2
6-(4-Fluorophenyl)-6-methyl-3-azabicyclo[3.1.0]hexane hydrochloride chemical structure, C12H15ClFN, CAS 2098336-23-1
6-(4-Fluorophenyl)-6-methyl-3-azabicyclo[3.1.0]hexane hydrochloride
CAS 2098336-23-1C12H15ClFN
6-(4-(Trifluoromethyl)phenyl)-3-azabicyclo[3.1.0]hexane hydrochloride chemical structure, C12H13ClF3N, CAS 1823259-46-6
6-(4-(Trifluoromethyl)phenyl)-3-azabicyclo[3.1.0]hexane hydrochloride
CAS 1823259-46-6C12H13ClF3N
(1R,5S,6R)-6-(2-Methylphenyl)-3-azabicyclo[3.1.0]hexane hydrochloride chemical structure, C12H16ClN, CAS 2751603-48-0
(1R,5S,6R)-6-(2-Methylphenyl)-3-azabicyclo[3.1.0]hexane hydrochloride
CAS 2751603-48-0C12H16ClN
(1R,5S,6R)-6-(2-Methylphenyl)-3-azabicyclo[3.1.0]hexane chemical structure, C12H15N, CAS 2751603-47-9
(1R,5S,6R)-6-(2-Methylphenyl)-3-azabicyclo[3.1.0]hexane
CAS 2751603-47-9C12H15N
tert-Butyl 6-(4-aminophenyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate chemical structure, C16H22N2O2, CAS 2357597-13-6
tert-Butyl 6-(4-aminophenyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate
CAS 2357597-13-6C16H22N2O2