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Murcko scaffold

Ring system with 2 rings and 21 atoms

17 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
21
Chemicals
17
With full pages
4
Scaffold SMILES

O=C(CCc1ccccc1)NCC(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCc1ccccc1)NCC(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

N-[2-(4-Fluoroanilino)-2-oxoethyl]-N-methyl-3-phenylpropanamide chemical structure, C18H19FN2O2, CAS 851399-03-6
N-[2-(4-Fluoroanilino)-2-oxoethyl]-N-methyl-3-phenylpropanamide
CAS 851399-03-6C18H19FN2O2
D-Phe-Val-p-nitroanilide chemical structure, C20H24N4O4, CAS 108321-89-7
D-Phe-Val-p-nitroanilide
CAS 108321-89-7C20H24N4O4
N-[2-(4-Chloroanilino)-2-oxoethyl]-N-methyl-3-phenylpropanamide chemical structure, C18H19ClN2O2, CAS 852464-62-1
N-[2-(4-Chloroanilino)-2-oxoethyl]-N-methyl-3-phenylpropanamide
CAS 852464-62-1C18H19ClN2O2
N-[2-(4-Methoxyanilino)-2-oxoethyl]-N-methyl-3-phenylpropanamide chemical structure, C19H22N2O3, CAS 876677-37-1
N-[2-(4-Methoxyanilino)-2-oxoethyl]-N-methyl-3-phenylpropanamide
CAS 876677-37-1C19H22N2O3
H-D-Ile-Phe-Lys-Pna chemical structure, C27H38N6O5, CAS 76626-41-0
H-D-Ile-Phe-Lys-Pna
CAS 76626-41-0C27H38N6O5
N-Phenyl-N~2~-[(2S)-3-phenyl-2-(sulfanylmethyl)propanoyl]-L-alpha-glutamine chemical structure, C21H24N2O4S, CAS 126349-24-4
N-Phenyl-N~2~-[(2S)-3-phenyl-2-(sulfanylmethyl)propanoyl]-L-alpha-glutamine
CAS 126349-24-4C21H24N2O4S
L-Phenylalanyl-N-(4-nitrophenyl)-L-alaninamide chemical structure, C18H20N4O4, CAS 69079-68-1
L-Phenylalanyl-N-(4-nitrophenyl)-L-alaninamide
CAS 69079-68-1C18H20N4O4
tert-Butyl N-[(2S)-1-[(2-anilino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]carbamate chemical structure, C22H27N3O4, CAS 148627-66-1
tert-Butyl N-[(2S)-1-[(2-anilino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]carbamate
CAS 148627-66-1C22H27N3O4
H-Ile-Phe-Lys-pNA chemical structure, C27H38N6O5, CAS 102292-71-7
H-Ile-Phe-Lys-pNA
CAS 102292-71-7C27H38N6O5
N-Formyl-L-alanyl-L-phenylalanyl-N-(4-nitrophenyl)-L-lysinamide chemical structure, C25H32N6O6, CAS 735256-05-0
N-Formyl-L-alanyl-L-phenylalanyl-N-(4-nitrophenyl)-L-lysinamide
CAS 735256-05-0C25H32N6O6
L-Leucyl-L-tyrosyl-N-(4-nitrophenyl)-L-alaninamide chemical structure, C24H31N5O6, CAS 791627-41-3
L-Leucyl-L-tyrosyl-N-(4-nitrophenyl)-L-alaninamide
CAS 791627-41-3C24H31N5O6
(2S)-2-[[(2R)-2-Amino-3-phenylpropanoyl]amino]-3-methyl-N-(4-nitrophenyl)butanamide chemical structure, C20H24N4O4
(2S)-2-[[(2R)-2-Amino-3-phenylpropanoyl]amino]-3-methyl-N-(4-nitrophenyl)butanamide
C20H24N4O4
D-Val-Phe-Lys p-Nitroanilide dihydrochloride chemical structure, C26H38Cl2N6O5, CAS 74551-31-8
D-Val-Phe-Lys p-Nitroanilide dihydrochloride
CAS 74551-31-8C26H38Cl2N6O5
Isovaleryl-Phe-Lys-pNA HCl chemical structure, C26H36ClN5O5, CAS 178894-43-4
Isovaleryl-Phe-Lys-pNA HCl
CAS 178894-43-4C26H36ClN5O5
h-Glu-ala-leu-phe-gln-pna chemical structure, C36H47F3N8O12, CAS 198551-00-7
h-Glu-ala-leu-phe-gln-pna
CAS 198551-00-7C36H47F3N8O12
(S)-2-(2-(2-Aminoacetamido)acetamido)-N-(2-((4-(hydroxymethyl)phenyl)amino)-2-oxoethyl)-3-phenylpropanamide chemical structure, C22H27N5O5, CAS 2632341-94-5
(S)-2-(2-(2-Aminoacetamido)acetamido)-N-(2-((4-(hydroxymethyl)phenyl)amino)-2-oxoethyl)-3-phenylpropanamide
CAS 2632341-94-5C22H27N5O5
D-Phe-val-P-nitroanilide tfa chemical structure, C22H25F3N4O6
D-Phe-val-P-nitroanilide tfa
C22H25F3N4O6