CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 21 atoms

14 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
21
Chemicals
14
With full pages
9
Scaffold SMILES

O=C(COC(=O)c1cccnc1)NCCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COC(=O)c1cccnc1)NCCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

[2-[2-(4-Methoxyphenyl)ethylamino]-2-oxoethyl] 5,6-dichloropyridine-3-carboxylate chemical structure, C17H16Cl2N2O4, CAS 380190-95-4
[2-[2-(4-Methoxyphenyl)ethylamino]-2-oxoethyl] 5,6-dichloropyridine-3-carboxylate
CAS 380190-95-4C17H16Cl2N2O4
[(2-Phenylethyl)carbamoyl]methyl 6-chloropyridine-3-carboxylate chemical structure, C16H15ClN2O3, CAS 502593-26-2
[(2-Phenylethyl)carbamoyl]methyl 6-chloropyridine-3-carboxylate
CAS 502593-26-2C16H15ClN2O3
{[2-(4-Fluorophenyl)ethyl]carbamoyl}methyl 2-chloropyridine-3-carboxylate chemical structure, C16H14ClFN2O3, CAS 522624-93-7
{[2-(4-Fluorophenyl)ethyl]carbamoyl}methyl 2-chloropyridine-3-carboxylate
CAS 522624-93-7C16H14ClFN2O3
{[2-(4-Fluorophenyl)ethyl]carbamoyl}methyl 6-chloropyridine-3-carboxylate chemical structure, C16H14ClFN2O3, CAS 437749-27-4
{[2-(4-Fluorophenyl)ethyl]carbamoyl}methyl 6-chloropyridine-3-carboxylate
CAS 437749-27-4C16H14ClFN2O3
[2-[2-(4-Chlorophenyl)ethylamino]-2-oxoethyl] 6-chloropyridine-3-carboxylate chemical structure, C16H14Cl2N2O3, CAS 474355-49-2
[2-[2-(4-Chlorophenyl)ethylamino]-2-oxoethyl] 6-chloropyridine-3-carboxylate
CAS 474355-49-2C16H14Cl2N2O3
{[2-(4-Methoxyphenyl)ethyl]carbamoyl}methyl 2-chloropyridine-3-carboxylate chemical structure, C17H17ClN2O4, CAS 389811-21-6
{[2-(4-Methoxyphenyl)ethyl]carbamoyl}methyl 2-chloropyridine-3-carboxylate
CAS 389811-21-6C17H17ClN2O4
2-{[2-(4-Chlorophenyl)ethyl]amino}-2-oxoethyl 5-bromopyridine-3-carboxylate chemical structure, C16H14BrClN2O3, CAS 502571-48-4
2-{[2-(4-Chlorophenyl)ethyl]amino}-2-oxoethyl 5-bromopyridine-3-carboxylate
CAS 502571-48-4C16H14BrClN2O3
2-Oxo-2-(phenethylamino)ethyl 2-(methylthio)nicotinate chemical structure, C17H18N2O3S, CAS 380549-74-6
2-Oxo-2-(phenethylamino)ethyl 2-(methylthio)nicotinate
CAS 380549-74-6C17H18N2O3S
[(2-Phenylethyl)carbamoyl]methyl 2-chloropyridine-3-carboxylate chemical structure, C16H15ClN2O3, CAS 479534-34-4
[(2-Phenylethyl)carbamoyl]methyl 2-chloropyridine-3-carboxylate
CAS 479534-34-4C16H15ClN2O3
{[2-(4-Sulfamoylphenyl)ethyl]carbamoyl}methyl 2-(methylsulfanyl)pyridine-3-carboxylate chemical structure, C17H19N3O5S2, CAS 875328-26-0
{[2-(4-Sulfamoylphenyl)ethyl]carbamoyl}methyl 2-(methylsulfanyl)pyridine-3-carboxylate
CAS 875328-26-0C17H19N3O5S2
[2-[2-(3,4-Diethoxyphenyl)ethylamino]-2-oxoethyl] 2-methylsulfanylpyridine-3-carboxylate chemical structure, C21H26N2O5S, CAS 878080-92-3
[2-[2-(3,4-Diethoxyphenyl)ethylamino]-2-oxoethyl] 2-methylsulfanylpyridine-3-carboxylate
CAS 878080-92-3C21H26N2O5S
[(2-Phenylpropyl)carbamoyl]methyl 2-chloropyridine-3-carboxylate chemical structure, C17H17ClN2O3, CAS 879148-84-2
[(2-Phenylpropyl)carbamoyl]methyl 2-chloropyridine-3-carboxylate
CAS 879148-84-2C17H17ClN2O3
{[2-(3,4-Diethoxyphenyl)ethyl]carbamoyl}methyl 2-chloropyridine-3-carboxylate chemical structure, C20H23ClN2O5, CAS 1016410-17-5
{[2-(3,4-Diethoxyphenyl)ethyl]carbamoyl}methyl 2-chloropyridine-3-carboxylate
CAS 1016410-17-5C20H23ClN2O5
{[2-(3,4-Diethoxyphenyl)ethyl]carbamoyl}methyl 6-chloropyridine-3-carboxylate chemical structure, C20H23ClN2O5, CAS 1031488-06-8
{[2-(3,4-Diethoxyphenyl)ethyl]carbamoyl}methyl 6-chloropyridine-3-carboxylate
CAS 1031488-06-8C20H23ClN2O5