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Murcko scaffold

Ring system with 2 rings and 17 atoms

59 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
59
With full pages
20
Scaffold SMILES

O=C(NN=Cc1ccccc1)c1cnccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)c1cnccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 59 chemicals

N'-(2,5-Dimethoxybenzylidene)-2-pyrazinecarbohydrazide chemical structure, C14H14N4O3, CAS 1323436-60-7
N'-(2,5-Dimethoxybenzylidene)-2-pyrazinecarbohydrazide
CAS 1323436-60-7C14H14N4O3
N'-[(E)-(4-tert-Butylphenyl)methylidene]-2-pyrazinecarbohydrazide chemical structure, C16H18N4O, CAS 304908-28-9
N'-[(E)-(4-tert-Butylphenyl)methylidene]-2-pyrazinecarbohydrazide
CAS 304908-28-9C16H18N4O
N'-(3,4-Dichlorobenzylidene)-2-pyrazinecarbohydrazide chemical structure, C12H8Cl2N4O, CAS 1323436-68-5
N'-(3,4-Dichlorobenzylidene)-2-pyrazinecarbohydrazide
CAS 1323436-68-5C12H8Cl2N4O
N'-[(Z)-(2,4-Dichlorophenyl)methylidene]pyrazine-2-carbohydrazide chemical structure, C12H8Cl2N4O
N'-[(Z)-(2,4-Dichlorophenyl)methylidene]pyrazine-2-carbohydrazide
C12H8Cl2N4O
Methyl 4-{(E)-[(2-pyrazinylcarbonyl)hydrazono]methyl}benzoate chemical structure, C14H12N4O3, CAS 304908-22-3
Methyl 4-{(E)-[(2-pyrazinylcarbonyl)hydrazono]methyl}benzoate
CAS 304908-22-3C14H12N4O3
N-[(E)-(3-Chlorophenyl)methylideneamino]pyrazine-2-carboxamide chemical structure, C12H9ClN4O, CAS 1206198-44-8
N-[(E)-(3-Chlorophenyl)methylideneamino]pyrazine-2-carboxamide
CAS 1206198-44-8C12H9ClN4O
N'-(2-Ethoxybenzylidene)-2-pyrazinecarbohydrazide chemical structure, C14H14N4O2, CAS 1263143-47-0
N'-(2-Ethoxybenzylidene)-2-pyrazinecarbohydrazide
CAS 1263143-47-0C14H14N4O2
N-[(E)-(4-Ethylphenyl)methylideneamino]pyrazine-2-carboxamide chemical structure, C14H14N4O, CAS 304908-04-1
N-[(E)-(4-Ethylphenyl)methylideneamino]pyrazine-2-carboxamide
CAS 304908-04-1C14H14N4O
N'-(4-Ethoxybenzylidene)-2-pyrazinecarbohydrazide chemical structure, C14H14N4O2, CAS 1206198-55-1
N'-(4-Ethoxybenzylidene)-2-pyrazinecarbohydrazide
CAS 1206198-55-1C14H14N4O2
N-[(E)-Benzylideneamino]pyrazine-2-carboxamide chemical structure, C12H10N4O, CAS 1206198-43-7
N-[(E)-Benzylideneamino]pyrazine-2-carboxamide
CAS 1206198-43-7C12H10N4O
N'-[(E)-(4-Chlorophenyl)methylidene]pyrazine-2-carbohydrazide chemical structure, C12H9ClN4O, CAS 926303-83-5
N'-[(E)-(4-Chlorophenyl)methylidene]pyrazine-2-carbohydrazide
CAS 926303-83-5C12H9ClN4O
N'-[(Z)-(2-Chlorophenyl)methylidene]pyrazine-2-carbohydrazide chemical structure, C12H9ClN4O, CAS 935886-78-5
N'-[(Z)-(2-Chlorophenyl)methylidene]pyrazine-2-carbohydrazide
CAS 935886-78-5C12H9ClN4O
Pyrazine-2-carboxylic acid (4-methyl-benzylidene)-hydrazide chemical structure, C13H12N4O, CAS 304908-52-9
Pyrazine-2-carboxylic acid (4-methyl-benzylidene)-hydrazide
CAS 304908-52-9C13H12N4O
N-[[4-(Diethylamino)phenyl]methylideneamino]pyrazine-2-carboxamide chemical structure, C16H19N5O, CAS 1078203-29-8
N-[[4-(Diethylamino)phenyl]methylideneamino]pyrazine-2-carboxamide
CAS 1078203-29-8C16H19N5O
N'-[(Z)-[4-(Propan-2-yl)phenyl]methylidene]pyrazine-2-carbohydrazide chemical structure, C15H16N4O, CAS 1239766-69-8
N'-[(Z)-[4-(Propan-2-yl)phenyl]methylidene]pyrazine-2-carbohydrazide
CAS 1239766-69-8C15H16N4O
N'-[(E)-1-(4-Methoxyphenyl)ethylidene]-2-pyrazinecarbohydrazide chemical structure, C14H14N4O2, CAS 304908-64-3
N'-[(E)-1-(4-Methoxyphenyl)ethylidene]-2-pyrazinecarbohydrazide
CAS 304908-64-3C14H14N4O2
N'-[(E)-1-(4-Chlorophenyl)ethylidene]-2-pyrazinecarbohydrazide chemical structure, C13H11ClN4O, CAS 304908-65-4
N'-[(E)-1-(4-Chlorophenyl)ethylidene]-2-pyrazinecarbohydrazide
CAS 304908-65-4C13H11ClN4O
N'-[(1Z)-1-(2,4-Dichlorophenyl)ethylidene]pyrazine-2-carbohydrazide chemical structure, C13H10Cl2N4O, CAS 315206-59-8
N'-[(1Z)-1-(2,4-Dichlorophenyl)ethylidene]pyrazine-2-carbohydrazide
CAS 315206-59-8C13H10Cl2N4O
N'-[(E)-(2,4,5-Trimethoxyphenyl)methylidene]pyrazine-2-carbohydrazide chemical structure, C15H16N4O4, CAS 304908-33-6
N'-[(E)-(2,4,5-Trimethoxyphenyl)methylidene]pyrazine-2-carbohydrazide
CAS 304908-33-6C15H16N4O4
N'-[(E)-(5-Bromo-2-methoxyphenyl)methylidene]-2-pyrazinecarbohydrazide chemical structure, C13H11BrN4O2, CAS 304908-14-3
N'-[(E)-(5-Bromo-2-methoxyphenyl)methylidene]-2-pyrazinecarbohydrazide
CAS 304908-14-3C13H11BrN4O2
N'-[(Z)-(3,4,5-Trimethoxyphenyl)methylidene]pyrazine-2-carbohydrazide chemical structure, C15H16N4O4, CAS 1239766-77-8
N'-[(Z)-(3,4,5-Trimethoxyphenyl)methylidene]pyrazine-2-carbohydrazide
CAS 1239766-77-8C15H16N4O4
N-[(E)-(2,4-Dimethoxyphenyl)methylideneamino]pyrazine-2-carboxamide chemical structure, C14H14N4O3, CAS 1260138-06-4
N-[(E)-(2,4-Dimethoxyphenyl)methylideneamino]pyrazine-2-carboxamide
CAS 1260138-06-4C14H14N4O3
N'-[(E)-(4-Fluorophenyl)methylidene]-2-pyrazinecarbohydrazide chemical structure, C12H9FN4O, CAS 1206198-47-1
N'-[(E)-(4-Fluorophenyl)methylidene]-2-pyrazinecarbohydrazide
CAS 1206198-47-1C12H9FN4O
N'-[(1Z)-1-(4-Fluorophenyl)ethylidene]pyrazine-2-carbohydrazide chemical structure, C13H11FN4O, CAS 315206-55-4
N'-[(1Z)-1-(4-Fluorophenyl)ethylidene]pyrazine-2-carbohydrazide
CAS 315206-55-4C13H11FN4O