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Murcko scaffold

Ring system with 3 rings and 24 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
8
With full pages
3
Scaffold SMILES

O=C(OCC(=O)N1CCN(c2ccccc2)CC1)c1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC(=O)N1CCN(c2ccccc2)CC1)c1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl 5,6-dichloropyridine-3-carboxylate chemical structure, C18H17Cl2N3O3, CAS 753472-33-2
2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl 5,6-dichloropyridine-3-carboxylate
CAS 753472-33-2C18H17Cl2N3O3
[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl] 1-oxidopyridin-1-ium-3-carboxylate chemical structure, C18H19N3O4, CAS 731782-96-0
[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl] 1-oxidopyridin-1-ium-3-carboxylate
CAS 731782-96-0C18H19N3O4
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl 2-chloropyridine-3-carboxylate chemical structure, C19H20ClN3O4, CAS 926537-64-6
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl 2-chloropyridine-3-carboxylate
CAS 926537-64-6C19H20ClN3O4
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl 6-chloropyridine-3-carboxylate chemical structure, C19H20ClN3O4, CAS 875460-80-3
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl 6-chloropyridine-3-carboxylate
CAS 875460-80-3C19H20ClN3O4
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl 5-bromopyridine-3-carboxylate chemical structure, C19H20BrN3O4, CAS 1210701-48-6
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl 5-bromopyridine-3-carboxylate
CAS 1210701-48-6C19H20BrN3O4
2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl 6-chloropyridine-3-carboxylate chemical structure, C18H18ClN3O3, CAS 1016356-18-5
2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl 6-chloropyridine-3-carboxylate
CAS 1016356-18-5C18H18ClN3O3
2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-oxoethyl 5-bromopyridine-3-carboxylate chemical structure, C18H17BrFN3O3, CAS 1210470-57-7
2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-oxoethyl 5-bromopyridine-3-carboxylate
CAS 1210470-57-7C18H17BrFN3O3
2-[4-(2-Fluorophenyl)piperazin-1-yl]-2-oxoethyl 5-bromopyridine-3-carboxylate chemical structure, C18H17BrFN3O3, CAS 1291837-66-5
2-[4-(2-Fluorophenyl)piperazin-1-yl]-2-oxoethyl 5-bromopyridine-3-carboxylate
CAS 1291837-66-5C18H17BrFN3O3