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Murcko scaffold

Ring system with 3 rings and 24 atoms

169 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 24
Chemicals: 169
With full pages: 11

Scaffold SMILES

O=C(COc1cnn(-c2ccccc2)c(=O)c1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(COc1cnn(-c2ccccc2)c(=O)c1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 169 chemicals

Ethyl 4-(2-anilino-2-oxoethoxy)-1-(2-methylphenyl)-6-oxopyridazine-3-carboxylate chemical structure, C22H21N3O5, CAS 899729-14-7

Ethyl 4-(2-anilino-2-oxoethoxy)-1-(2-methylphenyl)-6-oxopyridazine-3-carboxylate

CAS 899729-14-7C₂₂H₂₁N₃O₅

Ethyl 4-(2-anilino-2-oxoethoxy)-1-(4-methylphenyl)-6-oxopyridazine-3-carboxylate chemical structure, C22H21N3O5, CAS 899960-07-7

Ethyl 4-(2-anilino-2-oxoethoxy)-1-(4-methylphenyl)-6-oxopyridazine-3-carboxylate

CAS 899960-07-7C₂₂H₂₁N₃O₅

Ethyl 4-(2-anilino-2-oxoethoxy)-1-(4-fluorophenyl)-6-oxopyridazine-3-carboxylate chemical structure, C21H18FN3O5, CAS 899729-16-9

Ethyl 4-(2-anilino-2-oxoethoxy)-1-(4-fluorophenyl)-6-oxopyridazine-3-carboxylate

CAS 899729-16-9C₂₁H₁₈FN₃O₅

Ethyl 4-[2-(2-methylanilino)-2-oxoethoxy]-6-oxo-1-phenylpyridazine-3-carboxylate chemical structure, C22H21N3O5, CAS 899960-09-9

Ethyl 4-[2-(2-methylanilino)-2-oxoethoxy]-6-oxo-1-phenylpyridazine-3-carboxylate

CAS 899960-09-9C₂₂H₂₁N₃O₅

Ethyl 4-[2-(2-methylanilino)-2-oxoethoxy]-1-(4-methylphenyl)-6-oxopyridazine-3-carboxylate chemical structure, C23H23N3O5, CAS 899992-16-6

Ethyl 4-[2-(2-methylanilino)-2-oxoethoxy]-1-(4-methylphenyl)-6-oxopyridazine-3-carboxylate

CAS 899992-16-6C₂₃H₂₃N₃O₅

Ethyl 4-[2-(3-methylanilino)-2-oxoethoxy]-6-oxo-1-phenylpyridazine-3-carboxylate chemical structure, C22H21N3O5, CAS 899960-11-3

Ethyl 4-[2-(3-methylanilino)-2-oxoethoxy]-6-oxo-1-phenylpyridazine-3-carboxylate

CAS 899960-11-3C₂₂H₂₁N₃O₅

Ethyl 4-[2-(3-methylanilino)-2-oxoethoxy]-1-(2-methylphenyl)-6-oxopyridazine-3-carboxylate chemical structure, C23H23N3O5, CAS 899992-18-8

Ethyl 4-[2-(3-methylanilino)-2-oxoethoxy]-1-(2-methylphenyl)-6-oxopyridazine-3-carboxylate

CAS 899992-18-8C₂₃H₂₃N₃O₅

Ethyl 4-[2-(3-methylanilino)-2-oxoethoxy]-1-(4-methylphenyl)-6-oxopyridazine-3-carboxylate chemical structure, C23H23N3O5, CAS 899729-20-5

Ethyl 4-[2-(3-methylanilino)-2-oxoethoxy]-1-(4-methylphenyl)-6-oxopyridazine-3-carboxylate

CAS 899729-20-5C₂₃H₂₃N₃O₅

Ethyl 4-[2-(4-methylanilino)-2-oxoethoxy]-1-(2-methylphenyl)-6-oxopyridazine-3-carboxylate chemical structure, C23H23N3O5, CAS 899729-22-7

Ethyl 4-[2-(4-methylanilino)-2-oxoethoxy]-1-(2-methylphenyl)-6-oxopyridazine-3-carboxylate

CAS 899729-22-7C₂₃H₂₃N₃O₅

Ethyl 4-[2-(4-methylanilino)-2-oxoethoxy]-1-(4-methylphenyl)-6-oxopyridazine-3-carboxylate chemical structure, C23H23N3O5, CAS 899960-15-7

Ethyl 4-[2-(4-methylanilino)-2-oxoethoxy]-1-(4-methylphenyl)-6-oxopyridazine-3-carboxylate

CAS 899960-15-7C₂₃H₂₃N₃O₅

Ethyl 4-[2-(2,3-dimethylanilino)-2-oxoethoxy]-6-oxo-1-phenylpyridazine-3-carboxylate chemical structure, C23H23N3O5, CAS 899992-24-6

Ethyl 4-[2-(2,3-dimethylanilino)-2-oxoethoxy]-6-oxo-1-phenylpyridazine-3-carboxylate

CAS 899992-24-6C₂₃H₂₃N₃O₅

Ethyl 4-[2-(3,5-dimethylanilino)-2-oxoethoxy]-6-oxo-1-phenylpyridazine-3-carboxylate chemical structure, C23H23N3O5, CAS 899960-21-5

Ethyl 4-[2-(3,5-dimethylanilino)-2-oxoethoxy]-6-oxo-1-phenylpyridazine-3-carboxylate

CAS 899960-21-5C₂₃H₂₃N₃O₅

Ethyl 4-(2-((2,5-dimethylphenyl)amino)-2-oxoethoxy)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate chemical structure, C23H23N3O5, CAS 899992-30-4

Ethyl 4-(2-((2,5-dimethylphenyl)amino)-2-oxoethoxy)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate

CAS 899992-30-4C₂₃H₂₃N₃O₅

Ethyl 4-(2-((4-ethylphenyl)amino)-2-oxoethoxy)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate chemical structure, C23H23N3O5, CAS 899729-36-3

Ethyl 4-(2-((4-ethylphenyl)amino)-2-oxoethoxy)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate

CAS 899729-36-3C₂₃H₂₃N₃O₅

Ethyl 4-(2-((2,4-dimethylphenyl)amino)-2-oxoethoxy)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate chemical structure, C23H23N3O5, CAS 899992-38-2

Ethyl 4-(2-((2,4-dimethylphenyl)amino)-2-oxoethoxy)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate

CAS 899992-38-2C₂₃H₂₃N₃O₅

Ethyl 6-oxo-4-(2-oxo-2-((4-(trifluoromethyl)phenyl)amino)ethoxy)-1-phenyl-1,6-dihydropyridazine-3-carboxylate chemical structure, C22H18F3N3O5, CAS 899729-46-5

Ethyl 6-oxo-4-(2-oxo-2-((4-(trifluoromethyl)phenyl)amino)ethoxy)-1-phenyl-1,6-dihydropyridazine-3-carboxylate

CAS 899729-46-5C₂₂H₁₈F₃N₃O₅

Ethyl 1-(4-fluorophenyl)-6-oxo-4-(2-oxo-2-((4-(trifluoromethyl)phenyl)amino)ethoxy)-1,6-dihydropyridazine-3-carboxylate chemical structure, C22H17F4N3O5, CAS 899992-48-4

Ethyl 1-(4-fluorophenyl)-6-oxo-4-(2-oxo-2-((4-(trifluoromethyl)phenyl)amino)ethoxy)-1,6-dihydropyridazine-3-carboxylate

CAS 899992-48-4C₂₂H₁₇F₄N₃O₅

Ethyl 6-oxo-4-(2-oxo-2-((3-(trifluoromethyl)phenyl)amino)ethoxy)-1-phenyl-1,6-dihydropyridazine-3-carboxylate chemical structure, C22H18F3N3O5, CAS 899729-50-1

Ethyl 6-oxo-4-(2-oxo-2-((3-(trifluoromethyl)phenyl)amino)ethoxy)-1-phenyl-1,6-dihydropyridazine-3-carboxylate

CAS 899729-50-1C₂₂H₁₈F₃N₃O₅

Ethyl 1-(4-fluorophenyl)-6-oxo-4-(2-oxo-2-((3-(trifluoromethyl)phenyl)amino)ethoxy)-1,6-dihydropyridazine-3-carboxylate chemical structure, C22H17F4N3O5, CAS 899729-54-5

Ethyl 1-(4-fluorophenyl)-6-oxo-4-(2-oxo-2-((3-(trifluoromethyl)phenyl)amino)ethoxy)-1,6-dihydropyridazine-3-carboxylate

CAS 899729-54-5C₂₂H₁₇F₄N₃O₅

Ethyl 4-(2-((3-chloro-2-methylphenyl)amino)-2-oxoethoxy)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate chemical structure, C22H20ClN3O5, CAS 899733-68-7

Ethyl 4-(2-((3-chloro-2-methylphenyl)amino)-2-oxoethoxy)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate

CAS 899733-68-7C₂₂H₂₀ClN₃O₅

Ethyl 4-(2-((3-chloro-2-methylphenyl)amino)-2-oxoethoxy)-6-oxo-1-(p-tolyl)-1,6-dihydropyridazine-3-carboxylate chemical structure, C23H22ClN3O5, CAS 899944-05-9

Ethyl 4-(2-((3-chloro-2-methylphenyl)amino)-2-oxoethoxy)-6-oxo-1-(p-tolyl)-1,6-dihydropyridazine-3-carboxylate

CAS 899944-05-9C₂₃H₂₂ClN₃O₅

Ethyl 4-{[(3-chloro-2-methylphenyl)carbamoyl]methoxy}-1-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazine-3-carboxylate chemical structure, C22H19ClFN3O5, CAS 899975-86-1

Ethyl 4-{[(3-chloro-2-methylphenyl)carbamoyl]methoxy}-1-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazine-3-carboxylate

CAS 899975-86-1C₂₂H₁₉ClFN₃O₅

Ethyl 4-(2-((4-(methoxycarbonyl)phenyl)amino)-2-oxoethoxy)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate chemical structure, C23H21N3O7, CAS 899992-85-9

Ethyl 4-(2-((4-(methoxycarbonyl)phenyl)amino)-2-oxoethoxy)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate

CAS 899992-85-9C₂₃H₂₁N₃O₇

Ethyl 4-(2-((4-(methoxycarbonyl)phenyl)amino)-2-oxoethoxy)-6-oxo-1-(p-tolyl)-1,6-dihydropyridazine-3-carboxylate chemical structure, C24H23N3O7, CAS 899943-11-4

Ethyl 4-(2-((4-(methoxycarbonyl)phenyl)amino)-2-oxoethoxy)-6-oxo-1-(p-tolyl)-1,6-dihydropyridazine-3-carboxylate

CAS 899943-11-4C₂₄H₂₃N₃O₇