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Murcko scaffold

Ring system with 4 rings and 24 atoms

33 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
33
With full pages
6
Scaffold SMILES

O=C1CC(c2ccccc2)Cc2nc(Nc3ccccc3)ncc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC(c2ccccc2)Cc2nc(Nc3ccccc3)ncc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

2-[(4-Methoxyphenyl)amino]-7-phenyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C21H19N3O2, CAS 669724-46-3
2-[(4-Methoxyphenyl)amino]-7-phenyl-7,8-dihydroquinazolin-5(6H)-one
CAS 669724-46-3C21H19N3O2
7-(4-Methoxyphenyl)-2-[(4-methoxyphenyl)amino]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C22H21N3O3, CAS 714940-27-9
7-(4-Methoxyphenyl)-2-[(4-methoxyphenyl)amino]-7,8-dihydroquinazolin-5(6H)-one
CAS 714940-27-9C22H21N3O3
2-[(4-Methylphenyl)amino]-7-phenyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C21H19N3O, CAS 669724-44-1
2-[(4-Methylphenyl)amino]-7-phenyl-7,8-dihydroquinazolin-5(6H)-one
CAS 669724-44-1C21H19N3O
7-(4-Methoxyphenyl)-2-[(2-methoxyphenyl)amino]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C22H21N3O3, CAS 726199-33-3
7-(4-Methoxyphenyl)-2-[(2-methoxyphenyl)amino]-7,8-dihydroquinazolin-5(6H)-one
CAS 726199-33-3C22H21N3O3
2-[(2-Methoxyphenyl)amino]-7-phenyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C21H19N3O2, CAS 714923-55-4
2-[(2-Methoxyphenyl)amino]-7-phenyl-7,8-dihydroquinazolin-5(6H)-one
CAS 714923-55-4C21H19N3O2
2-((2,4-Dichlorophenyl)amino)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C21H17Cl2N3O2, CAS 714235-05-9
2-((2,4-Dichlorophenyl)amino)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one
CAS 714235-05-9C21H17Cl2N3O2
7-(4-Chlorophenyl)-2-[(4-ethylphenyl)amino]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C22H20ClN3O, CAS 714286-50-7
7-(4-Chlorophenyl)-2-[(4-ethylphenyl)amino]-7,8-dihydroquinazolin-5(6H)-one
CAS 714286-50-7C22H20ClN3O
7-(4-Fluorophenyl)-2-[(3-methylphenyl)amino]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C21H18FN3O, CAS 714925-70-9
7-(4-Fluorophenyl)-2-[(3-methylphenyl)amino]-7,8-dihydroquinazolin-5(6H)-one
CAS 714925-70-9C21H18FN3O
2-[(3,5-Dimethylphenyl)amino]-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C23H23N3O2, CAS 714248-00-7
2-[(3,5-Dimethylphenyl)amino]-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one
CAS 714248-00-7C23H23N3O2
7-(4-Methylphenyl)-2-[(3-methylphenyl)amino]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C22H21N3O, CAS 714925-61-8
7-(4-Methylphenyl)-2-[(3-methylphenyl)amino]-7,8-dihydroquinazolin-5(6H)-one
CAS 714925-61-8C22H21N3O
7-(3-Chlorophenyl)-2-[(4-methoxyphenyl)amino]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C21H18ClN3O2, CAS 714225-36-2
7-(3-Chlorophenyl)-2-[(4-methoxyphenyl)amino]-7,8-dihydroquinazolin-5(6H)-one
CAS 714225-36-2C21H18ClN3O2
2-[(4-Ethylphenyl)amino]-7-phenyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C22H21N3O, CAS 714926-09-7
2-[(4-Ethylphenyl)amino]-7-phenyl-7,8-dihydroquinazolin-5(6H)-one
CAS 714926-09-7C22H21N3O
2-[(2,4-Dimethylphenyl)amino]-7-phenyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C22H21N3O, CAS 714930-64-0
2-[(2,4-Dimethylphenyl)amino]-7-phenyl-7,8-dihydroquinazolin-5(6H)-one
CAS 714930-64-0C22H21N3O
2-[(2,4-Dimethylphenyl)amino]-7-(4-fluorophenyl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C22H20FN3O, CAS 713094-70-3
2-[(2,4-Dimethylphenyl)amino]-7-(4-fluorophenyl)-7,8-dihydroquinazolin-5(6H)-one
CAS 713094-70-3C22H20FN3O
2-[(4-Ethylphenyl)amino]-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C23H23N3O2, CAS 714920-38-4
2-[(4-Ethylphenyl)amino]-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one
CAS 714920-38-4C23H23N3O2
7-(4-Chlorophenyl)-2-[(4-fluorophenyl)amino]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C20H15ClFN3O, CAS 714235-21-9
7-(4-Chlorophenyl)-2-[(4-fluorophenyl)amino]-7,8-dihydroquinazolin-5(6H)-one
CAS 714235-21-9C20H15ClFN3O
2-[(4-Methoxyphenyl)amino]-7-(4-methylphenyl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C22H21N3O2, CAS 714286-73-4
2-[(4-Methoxyphenyl)amino]-7-(4-methylphenyl)-7,8-dihydroquinazolin-5(6H)-one
CAS 714286-73-4C22H21N3O2
2-[(2,4-Dimethylphenyl)amino]-7-(4-methylphenyl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C23H23N3O, CAS 714939-19-2
2-[(2,4-Dimethylphenyl)amino]-7-(4-methylphenyl)-7,8-dihydroquinazolin-5(6H)-one
CAS 714939-19-2C23H23N3O
2-[(4-Fluorophenyl)amino]-7-phenyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C20H16FN3O, CAS 714945-97-8
2-[(4-Fluorophenyl)amino]-7-phenyl-7,8-dihydroquinazolin-5(6H)-one
CAS 714945-97-8C20H16FN3O
2-[(3,5-Dimethylphenyl)amino]-7-(4-methylphenyl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C23H23N3O, CAS 714234-96-5
2-[(3,5-Dimethylphenyl)amino]-7-(4-methylphenyl)-7,8-dihydroquinazolin-5(6H)-one
CAS 714234-96-5C23H23N3O
7-(4-Fluorophenyl)-2-[(4-methoxyphenyl)amino]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C21H18FN3O2, CAS 714924-64-8
7-(4-Fluorophenyl)-2-[(4-methoxyphenyl)amino]-7,8-dihydroquinazolin-5(6H)-one
CAS 714924-64-8C21H18FN3O2
2-[(3-Methylphenyl)amino]-7-phenyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C21H19N3O, CAS 713127-05-0
2-[(3-Methylphenyl)amino]-7-phenyl-7,8-dihydroquinazolin-5(6H)-one
CAS 713127-05-0C21H19N3O
2-[(3,5-Dichlorophenyl)amino]-7-phenyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C20H15Cl2N3O, CAS 714945-18-3
2-[(3,5-Dichlorophenyl)amino]-7-phenyl-7,8-dihydroquinazolin-5(6H)-one
CAS 714945-18-3C20H15Cl2N3O
7-(4-Fluorophenyl)-2-[(4-fluorophenyl)amino]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C20H15F2N3O, CAS 714235-58-2
7-(4-Fluorophenyl)-2-[(4-fluorophenyl)amino]-7,8-dihydroquinazolin-5(6H)-one
CAS 714235-58-2C20H15F2N3O