Murcko scaffold
Ring system with 3 rings and 15 atoms
45 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 15
- Chemicals
- 45
- With full pages
- 6
Scaffold SMILES
O=c1[nH]cnc2c1[nH]c[n+]2C1CCCO1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1[nH]cnc2c1[nH]c[n+]2C1CCCO1](/scaffold/JBXHFRZBULGPSC-UHFFFAOYSA-O/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 45 of 45 chemicals
1,7-Dimethylguanosine
CAS 26624-46-4C12H18N5O5+
7-Methylguanosine-5'-monophosphate
CAS 10162-58-0C11H17N5O8P+
7-Methyl-guanosine-5'-triphosphate
C11H19N5O14P3+
N(2),N(2),7-Trimethylguanosine
CAS 40027-70-1C13H20N5O5+
7-Methylguanosine
CAS 20244-86-4C11H16N5O5+
7-Methyl-GTP
CAS 26554-26-7C11H18N5O14P3
7-Methylguanosine 5'-(trihydrogen diphosphate)
CAS 117723-13-4C11H18N5O11P2+
Guanosine 5'-(tetrahydrogen triphosphate), 7-methyl-, inner salt
C11H18N5O14P3
1H-Purinium, 2-amino-7-(2-bromoethyl-1,2-d2)-6,9-dihydro-6-oxo-9-beta-D-ribofuranosyl-
CAS 113793-53-6C12H17BrN5O5+
1H-Purinium, 2-amino-7-(2-chloroethyl-2,2-d2)-6,9-dihydro-6-oxo-9-beta-D-ribofuranosyl-
CAS 113793-57-0C12H17ClN5O5+
7-Ethylguanosine
CAS 71369-24-9C12H18N5O5+
7-Methyl-2-deoxyguanosine
CAS 28074-91-1C11H16N5O4+
(Platinum(ethylenediamine)(guanosine)(2))(2+) cation
CAS 57574-64-8C44H74Cl3IN24O22Pt2+2
N(7)-Ethyldeoxyguanosine 5'-triphosphate
CAS 122055-03-2C12H20N5O13P3
Fluoroethylguanosine
CAS 70650-86-1C12H16FN5O5
7-(2,3-Dihydroxypropane)deoxyguanosine
CAS 104764-31-0C13H20N5O6+
7-(3-Trichloro-2-hydroxypropane)deoxyguanosine
CAS 104783-28-0C13H17Cl3N5O5+
7-(3-Chloro-2-hydroxypropane)deoxyguanosine
CAS 104783-29-1C13H19ClN5O5+
7-Methylguanosine 5'-triphosphate
C11H18N5O14P3
7-(2-Chloroethyl)guanosine
CAS 100550-99-0C12H17ClN5O5+
1H-Purinium, 2-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl)-6,9-dihydro-7-(2-hydroxyethyl)-6-oxo-
CAS 76702-32-4C12H18N5O5+
7-(delta-Hydroxybutyl)guanosine
CAS 74746-57-9C14H22N5O6+
![[[5-(2-Amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate chemical structure, C11H19N5O14P3+](/s/DKVRNHPCAOHRSI-UHFFFAOYSA-O.svg)
[[5-(2-Amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
C11H19N5O14P3+
7-Methylinosine
CAS 20245-33-4C11H15N4O5+
- Guanosine, 7-(2-bromoethyl)-105382-71-6C12H17BrN5O5+
- Guanosine 5'-(trihydrogen diphosphate), 7-methyl-, inner salt26467-11-8C11H17N5O11P2
- 6-Hydroxy-9-[5-O-(hydroxy{[(phosphonooxy)phosphinato]oxy}phosphoryl)-D-ribofuranosyl]-2-imino-7-methyl-3,9-dihydro-2H-purin-7-iumC11H18N5O14P3
- 7-Methyldeoxyguanosine triphosphate trisodium104809-10-1C11H15N5Na3O13P3
- 9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7-methyl-2,6-dioxo-1,2,6,9-tetrahydropurin-7-ium-3-ide58526-73-1C11H14N4O6
- 7-Methylguanosine 5'-diphosphate (sodium)2280018-77-9C11H16N5NaO11P2
- Guanosine, 7-methyl-, iodide (1:1)81100-62-1C11H16IN5O5
- 7-Methyldeoxyguanosine triphosphate trisodiumC11H15N5Na3O13P3
- 7-Methyl-5'-guanylic acid iodide1624566-94-4C11H17IN5O8P
- 7-Methyl-5'-guanylic acid chloride118941-61-0C11H17ClN5O8P
- 7-Methylguanosine 5'-diphosphate, N,N-diethylethanamine(1:2)1262968-09-1C23H47N7O11P2
- P-P-m7Gua-Ribf3Me.TEA2089461-52-7C18H34N6O11P2
- ((2R,3R,4R,5R)-5-(2-Amino-7-methyl-6-oxo-3,6-dihydro-9H-purin-7-ium-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen phosphate94889-79-9C12H18N5O8P
- 2-Amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl]-7-methyl-6-oxo-6,9-dihydro-1H-purin-7-ium IodideC12H18IN5O5
- [(2R,3S,4R,5R)-3,4-Dihydroxy-5-(7-methyl-6-oxo-1H-purin-9-ium-9-yl)oxolan-2-yl]methyl [hydroxy(phosphonooxy)phosphoryl] phosphate1446012-56-1C11H17N4O14P3
- 7-Methylguanosine 5'-monophosphate-d322976-65-4C11H16N5O8P
- [(2R,3S,4R,5R)-5-(2-Amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-4-hydroxy-3-methoxyoxolan-2-yl]methyl phosphono phosphate400806-44-2C12H19N5O11P2
- 7-Methylguanosine 5'-(trihydrogen diphosphate) triethylamine salt240137-50-2C17H32N6O11P2
- 2-Amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-7-methyl-1H-purin-9-ium-6-one iodide1093268-98-4C12H18IN5O5
- Guanosine impurity 5 triethylamine852155-74-9C17H32N6O11P2
- p-M7gua-ribf3Me94889-80-2C12H18N5O8P
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