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Murcko scaffold

Ring system with 3 rings and 15 atoms

80 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
80
With full pages
9
Scaffold SMILES

O=c1[nH]cnc2c1ccn2C1CCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]cnc2c1ccn2C1CCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 80 chemicals

Cadeguomycin chemical structure, C12H14N4O7, CAS 81645-08-1
Cadeguomycin
CAS 81645-08-1C12H14N4O7
4-Hydroxy-7-pentofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide chemical structure, C12H15N5O5, CAS 22242-93-9
4-Hydroxy-7-pentofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide
CAS 22242-93-9C12H15N5O5
7-Deaza-7-iodo-2'-deoxyguanosine chemical structure, C11H13IN4O4, CAS 172163-62-1
7-Deaza-7-iodo-2'-deoxyguanosine
CAS 172163-62-1C11H13IN4O4
7-Deazainosine chemical structure, C11H13N3O5, CAS 2862-16-0
7-Deazainosine
CAS 2862-16-0C11H13N3O5
Poly(7-deazainosinic acid) chemical structure, C11H14N3O8P, CAS 53794-83-5
Poly(7-deazainosinic acid)
CAS 53794-83-5C11H14N3O8P
7-Deazaguanosine chemical structure, C11H14N4O5, CAS 62160-23-0
7-Deazaguanosine
CAS 62160-23-0C11H14N4O5
7-Deaza-2'-deoxyguanosine chemical structure, C11H14N4O4, CAS 86392-75-8
7-Deaza-2'-deoxyguanosine
CAS 86392-75-8C11H14N4O4
7-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-3H-pyrrolo[2,3-d]pyrimidine-5-carbothioamide chemical structure, C12H14N4O5S, CAS 22242-95-1
7-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-3H-pyrrolo[2,3-d]pyrimidine-5-carbothioamide
CAS 22242-95-1C12H14N4O5S
2-Amino-7-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one chemical structure, C12H16N4O5, CAS 443642-38-4
2-Amino-7-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one
CAS 443642-38-4C12H16N4O5
7-Deaza-GTP chemical structure, C11H17N4O14P3, CAS 181356-39-8
7-Deaza-GTP
CAS 181356-39-8C11H17N4O14P3
7-Deaza-2'-c-methylinosine chemical structure, C12H15N3O5, CAS 443642-45-3
7-Deaza-2'-c-methylinosine
CAS 443642-45-3C12H15N3O5
5-Bromo-7-pentofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol chemical structure, C11H12BrN3O5, CAS 24386-96-7
5-Bromo-7-pentofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol
CAS 24386-96-7C11H12BrN3O5
4-Hydroxy-7-pentofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide chemical structure, C12H14N4O6, CAS 22242-94-0
4-Hydroxy-7-pentofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide
CAS 22242-94-0C12H14N4O6
7-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-N'-hydroxy-4-oxo-3H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide chemical structure, C12H15N5O6, CAS 22242-92-8
7-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-N'-hydroxy-4-oxo-3H-pyrrolo[2,3-d]pyrimidine-5-carboximidamide
CAS 22242-92-8C12H15N5O6
2-Amino-7-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-tetrahydrofuran-2-yl]-3H-pyrrolo[2,3-d]pyrimidin-4-one chemical structure, C12H16N4O5, CAS 444018-81-9
2-Amino-7-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-tetrahydrofuran-2-yl]-3H-pyrrolo[2,3-d]pyrimidin-4-one
CAS 444018-81-9C12H16N4O5
5-(Aminomethyl)-7-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-pyrrolo[2,3-d]pyrimidin-4-one chemical structure, C12H16N4O5, CAS 3724-93-4
5-(Aminomethyl)-7-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-pyrrolo[2,3-d]pyrimidin-4-one
CAS 3724-93-4C12H16N4O5
7-Cyano-7-deazaguanosine chemical structure, C12H13N5O5, CAS 61210-21-7
7-Cyano-7-deazaguanosine
CAS 61210-21-7C12H13N5O5
1H-Pyrrolo[2,3-d]pyrimidine-5-carboxylicacid,2-amino-7-(2-deoxy-|A-D-erythro-pentofuranosyl)-4,7-dihydro-4-oxo- chemical structure, C12H14N4O6, CAS 124738-85-8
1H-Pyrrolo[2,3-d]pyrimidine-5-carboxylicacid,2-amino-7-(2-deoxy-|A-D-erythro-pentofuranosyl)-4,7-dihydro-4-oxo-
CAS 124738-85-8C12H14N4O6
[3,4-Diacetyloxy-5-(4-oxo-1H-pyrrolo[2,3-d]pyrimidin-7-yl)oxolan-2-yl]methyl acetate chemical structure, C17H19N3O8, CAS 16754-78-2
[3,4-Diacetyloxy-5-(4-oxo-1H-pyrrolo[2,3-d]pyrimidin-7-yl)oxolan-2-yl]methyl acetate
CAS 16754-78-2C17H19N3O8
Ethyl 4-oxo-7-pentofuranosyl-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidine-5-carboximidate--hydrogen chloride (1/1) chemical structure, C14H19ClN4O6, CAS 22242-98-4
Ethyl 4-oxo-7-pentofuranosyl-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidine-5-carboximidate--hydrogen chloride (1/1)
CAS 22242-98-4C14H19ClN4O6
7-Deaza-3'F-2', 3'-dideoxyGTP chemical structure, C11H16FN4O12P3, CAS 136859-52-4
7-Deaza-3'F-2', 3'-dideoxyGTP
CAS 136859-52-4C11H16FN4O12P3
2'-Deoxy-7-deazaguanosine triphosphate chemical structure, C11H17N4O13P3, CAS 101515-08-6
2'-Deoxy-7-deazaguanosine triphosphate
CAS 101515-08-6C11H17N4O13P3
2-Amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile chemical structure, C12H13N5O4
2-Amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
C12H13N5O4
7-Iodo-2',3'-dideoxy-7-deaza-guanosine chemical structure, C11H13IN4O3, CAS 114748-67-3
7-Iodo-2',3'-dideoxy-7-deaza-guanosine
CAS 114748-67-3C11H13IN4O3