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Murcko scaffold

Ring system with 5 rings and 19 atoms

519 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
19
Chemicals
519
With full pages
80
Scaffold SMILES

c1ccc2c(CC3CC4CCN3CC4)ccnc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2c(CC3CC4CCN3CC4)ccnc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 519 chemicals

Quinidine N-oxide chemical structure, C20H24N2O3, CAS 109906-48-1
Quinidine N-oxide
CAS 109906-48-1C20H24N2O3
Quinine N-oxide chemical structure, C20H24N2O3
Quinine N-oxide
C20H24N2O3
(8I+/-,9R)-10,11-Dihydro-6a(2)-methoxycinchonan-9,10,11-triol chemical structure, C20H26N2O4, CAS 78549-62-9
(8I+/-,9R)-10,11-Dihydro-6a(2)-methoxycinchonan-9,10,11-triol
CAS 78549-62-9C20H26N2O4
4-[(S)-{5-Ethyl-1-azabicyclo[2.2.2]octan-2-yl}(hydroxy)methyl]quinolin-6-ol chemical structure, C19H24N2O2
4-[(S)-{5-Ethyl-1-azabicyclo[2.2.2]octan-2-yl}(hydroxy)methyl]quinolin-6-ol
C19H24N2O2
(9R)-9-{[tert-Butyl(dimethyl)silyl]oxy}-6'-methoxy-8alpha-10,11-dihydrocinchonan-11-ol chemical structure, C26H40N2O3Si, CAS 183994-18-5
(9R)-9-{[tert-Butyl(dimethyl)silyl]oxy}-6'-methoxy-8alpha-10,11-dihydrocinchonan-11-ol
CAS 183994-18-5C26H40N2O3Si
10,11-Didehydrocinchonidine chemical structure, C19H20N2O, CAS 157253-80-0
10,11-Didehydrocinchonidine
CAS 157253-80-0C19H20N2O
(S)-(6-Methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanamine chemical structure, C20H25N3O, CAS 757124-31-5
(S)-(6-Methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanamine
CAS 757124-31-5C20H25N3O
(8alpha,9S)-6'-Methoxycinchonan-9-amine chemical structure, C20H25N3O, CAS 168960-95-0
(8alpha,9S)-6'-Methoxycinchonan-9-amine
CAS 168960-95-0C20H25N3O
(9R)-10,11-Dihydro-6'-methoxycinchonan-9-amine chemical structure, C20H27N3O, CAS 522600-31-3
(9R)-10,11-Dihydro-6'-methoxycinchonan-9-amine
CAS 522600-31-3C20H27N3O
Quinine sulfate chemical structure, C40H50N4O8S, CAS 804-63-7
Quinine sulfate
CAS 804-63-7C40H50N4O8S
(1S,2R,4S,5R)-2-((S)-(6-Methoxyquinolin-4-yl)((trimethylsilyl)oxy)methyl)-5-vinylquinuclidine hydrochloride chemical structure, C23H33ClN2O2Si, CAS 931581-06-5
(1S,2R,4S,5R)-2-((S)-(6-Methoxyquinolin-4-yl)((trimethylsilyl)oxy)methyl)-5-vinylquinuclidine hydrochloride
CAS 931581-06-5C23H33ClN2O2Si
(S)-[(2S,4S,5R)-5-Ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanamine chemical structure, C20H27N3O, CAS 852913-53-2
(S)-[(2S,4S,5R)-5-Ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanamine
CAS 852913-53-2C20H27N3O
Quinine hydrochloride dihydrate chemical structure, C20H29ClN2O4, CAS 6119-47-7
Quinine hydrochloride dihydrate
CAS 6119-47-7C20H29ClN2O4
Quinine sulfate dihydrate chemical structure, C40H54N4O10S, CAS 207671-44-1
Quinine sulfate dihydrate
CAS 207671-44-1C40H54N4O10S
Hydroquinidine hydrochloride chemical structure, C20H27ClN2O2, CAS 1476-98-8
Hydroquinidine hydrochloride
CAS 1476-98-8C20H27ClN2O2
Ethylhydrocupreine hydrochloride chemical structure, C21H29ClN2O2, CAS 3413-58-9
Ethylhydrocupreine hydrochloride
CAS 3413-58-9C21H29ClN2O2
(1R)-(6-Methoxyquinolin-4-yl)((2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol hydrochloride hydrate chemical structure, C20H27ClN2O3, CAS 96304-72-2
(1R)-(6-Methoxyquinolin-4-yl)((2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol hydrochloride hydrate
CAS 96304-72-2C20H27ClN2O3
Quinidine hydrochloride monohydrate chemical structure, C20H27ClN2O3, CAS 6151-40-2
Quinidine hydrochloride monohydrate
CAS 6151-40-2C20H27ClN2O3
Quinidine sulfate salt dihydrate chemical structure, C40H54N4O10S
Quinidine sulfate salt dihydrate
C40H54N4O10S
(R)-Quinolin-4-yl((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl acetate chemical structure, C21H24N2O2, CAS 14075-54-8
(R)-Quinolin-4-yl((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl acetate
CAS 14075-54-8C21H24N2O2
(5-Ethylquinuclidin-2-yl)(quinolin-4-yl)methanamine chemical structure, C19H25N3, CAS 1355995-89-9
(5-Ethylquinuclidin-2-yl)(quinolin-4-yl)methanamine
CAS 1355995-89-9C19H25N3
(5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-(6-methoxyquinolin-4-yl)methanol, 2,3,4,5-tetrahydroxy-6-oxohexanoic acid chemical structure, C26H34N2O9, CAS 27555-34-6
(5-Ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-(6-methoxyquinolin-4-yl)methanol, 2,3,4,5-tetrahydroxy-6-oxohexanoic acid
CAS 27555-34-6C26H34N2O9
Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, hydrobromide, hydrate (1:1:?), (8alpha,9R)- chemical structure, C20H29BrN2O3, CAS 207386-86-5
Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, hydrobromide, hydrate (1:1:?), (8alpha,9R)-
CAS 207386-86-5C20H29BrN2O3
Quinine gluconate chemical structure, C26H36N2O9, CAS 4325-25-1
Quinine gluconate
CAS 4325-25-1C26H36N2O9