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Murcko scaffold

Ring system with 5 rings and 20 atoms

6 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
20
Chemicals
6
With full pages
3
Scaffold SMILES

O=C(c1ccnc2ccccc12)C1CC2CCN1CC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccnc2ccccc12)C1CC2CCN1CC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

(6-Methoxyquinolin-4-yl)(5-vinylquinuclidin-2-yl)methanone chemical structure, C20H22N2O2, CAS 569329-55-1
(6-Methoxyquinolin-4-yl)(5-vinylquinuclidin-2-yl)methanone
CAS 569329-55-1C20H22N2O2
Quinidinone chemical structure, C20H22N2O2, CAS 14528-53-1
Quinidinone
CAS 14528-53-1C20H22N2O2
4-Quinolinyl(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanone chemical structure, C19H20N2O, CAS 1397202-05-9
4-Quinolinyl(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanone
CAS 1397202-05-9C19H20N2O
(8alpha)-6'-Methoxycinchonan-9-one chemical structure, C20H22N2O2, CAS 84-31-1
(8alpha)-6'-Methoxycinchonan-9-one
CAS 84-31-1C20H22N2O2
Quininone hydrochloride chemical structure, C20H23ClN2O2, CAS 6119-73-9
Quininone hydrochloride
CAS 6119-73-9C20H23ClN2O2
6'-Methoxy-8alpha-10,11-dihydrocinchonan-9-one chemical structure, C20H24N2O2, CAS 26695-24-9
6'-Methoxy-8alpha-10,11-dihydrocinchonan-9-one
CAS 26695-24-9C20H24N2O2