CompoundList
Sign in
Murcko scaffold

4-Phenyl-2-(pyridin-3-yl)thiazole scaffold

40 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
40
With full pages
12
Scaffold SMILES

c1ccc(-c2csc(-c3cccnc3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenyl-2-(pyridin-3-yl)thiazole page
Murcko scaffold c1ccc(-c2csc(-c3cccnc3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

3-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]pyridine chemical structure, C14H9FN2S, CAS 380571-27-7
3-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]pyridine
CAS 380571-27-7C14H9FN2S
4-Phenyl-2-(pyridin-3-yl)thiazole chemical structure, C14H10N2S, CAS 70031-86-6
4-Phenyl-2-(pyridin-3-yl)thiazole
CAS 70031-86-6C14H10N2S
3-[4-(3-Fluoro-4-methoxyphenyl)-1,3-thiazol-2-yl]pyridine chemical structure, C15H11FN2OS, CAS 222629-51-8
3-[4-(3-Fluoro-4-methoxyphenyl)-1,3-thiazol-2-yl]pyridine
CAS 222629-51-8C15H11FN2OS
3-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]pyridine chemical structure, C15H12N2OS, CAS 222629-46-1
3-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]pyridine
CAS 222629-46-1C15H12N2OS
3-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]pyridine chemical structure, C14H9ClN2S, CAS 71541-39-4
3-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]pyridine
CAS 71541-39-4C14H9ClN2S
4-[2-(Pyridin-3-yl)-1,3-thiazol-4-yl]benzene-1,3-diol chemical structure, C14H10N2O2S, CAS 457943-99-6
4-[2-(Pyridin-3-yl)-1,3-thiazol-4-yl]benzene-1,3-diol
CAS 457943-99-6C14H10N2O2S
N,N-Dimethyl-4-[2-(3-pyridinyl)-1,3-thiazol-4-yl]benzenesulfonamide chemical structure, C16H15N3O2S2, CAS 618063-17-5
N,N-Dimethyl-4-[2-(3-pyridinyl)-1,3-thiazol-4-yl]benzenesulfonamide
CAS 618063-17-5C16H15N3O2S2
4-(4-Ethylphenyl)-2-pyridin-3-yl-1,3-thiazole chemical structure, C16H14N2S, CAS 428856-58-0
4-(4-Ethylphenyl)-2-pyridin-3-yl-1,3-thiazole
CAS 428856-58-0C16H14N2S
3-[4-(2,5-Dimethylphenyl)-1,3-thiazol-2-yl]pyridine chemical structure, C16H14N2S, CAS 429653-03-2
3-[4-(2,5-Dimethylphenyl)-1,3-thiazol-2-yl]pyridine
CAS 429653-03-2C16H14N2S
N-[4-(2-Pyridin-3-yl-thiazol-4-yl)-phenyl]-acetamide chemical structure, C16H13N3OS, CAS 429641-43-0
N-[4-(2-Pyridin-3-yl-thiazol-4-yl)-phenyl]-acetamide
CAS 429641-43-0C16H13N3OS
4-(4-Methoxy-3-methylphenyl)-2-pyridin-3-yl-1,3-thiazole chemical structure, C16H14N2OS, CAS 457944-00-2
4-(4-Methoxy-3-methylphenyl)-2-pyridin-3-yl-1,3-thiazole
CAS 457944-00-2C16H14N2OS
4-(2-Pyridin-3-yl-1,3-thiazol-4-yl)aniline chemical structure, C14H11N3S, CAS 92165-08-7
4-(2-Pyridin-3-yl-1,3-thiazol-4-yl)aniline
CAS 92165-08-7C14H11N3S
2-[4-(4-Methylphenyl)-2-(pyridin-3-yl)-1,3-thiazol-5-yl]acetic acid chemical structure, C17H14N2O2S, CAS 554438-65-2
2-[4-(4-Methylphenyl)-2-(pyridin-3-yl)-1,3-thiazol-5-yl]acetic acid
CAS 554438-65-2C17H14N2O2S
N,N-Diethyl-3-[2-(pyridin-3-yl)-1,3-thiazol-4-yl]benzenesulfonamide chemical structure, C18H19N3O2S2, CAS 845668-29-3
N,N-Diethyl-3-[2-(pyridin-3-yl)-1,3-thiazol-4-yl]benzenesulfonamide
CAS 845668-29-3C18H19N3O2S2
3-[4-(2,3,4-Trichlorophenyl)-1,3-thiazol-2-yl]pyridine chemical structure, C14H7Cl3N2S, CAS 521280-23-9
3-[4-(2,3,4-Trichlorophenyl)-1,3-thiazol-2-yl]pyridine
CAS 521280-23-9C14H7Cl3N2S
2-[4-(4-Bromophenyl)-2-(pyridin-3-yl)-1,3-thiazol-5-yl]acetic acid chemical structure, C16H11BrN2O2S, CAS 554423-29-9
2-[4-(4-Bromophenyl)-2-(pyridin-3-yl)-1,3-thiazol-5-yl]acetic acid
CAS 554423-29-9C16H11BrN2O2S
6-Methyl-5-(4-phenyl-1,3-thiazol-2-yl)-2-(trifluoromethyl)pyridine-3-carboxylic acid chemical structure, C17H11F3N2O2S, CAS 651004-85-2
6-Methyl-5-(4-phenyl-1,3-thiazol-2-yl)-2-(trifluoromethyl)pyridine-3-carboxylic acid
CAS 651004-85-2C17H11F3N2O2S
4-(4-Bromophenyl)-2-pyridin-3-yl-1,3-thiazole chemical structure, C14H9BrN2S, CAS 70031-93-5
4-(4-Bromophenyl)-2-pyridin-3-yl-1,3-thiazole
CAS 70031-93-5C14H9BrN2S
5-Thiazolecarboxamide, N,N-dimethyl-4-phenyl-2-(3-pyridinyl)-, hydrochloride (1:1) chemical structure, C17H16ClN3OS, CAS 51492-90-1
5-Thiazolecarboxamide, N,N-dimethyl-4-phenyl-2-(3-pyridinyl)-, hydrochloride (1:1)
CAS 51492-90-1C17H16ClN3OS
3-{4-[2,3-Dichloro-4-(ethylsulfonyl)phenyl]-1,3-thiazol-2-yl}pyridine chemical structure, C16H12Cl2N2O2S2, CAS 672951-40-5
3-{4-[2,3-Dichloro-4-(ethylsulfonyl)phenyl]-1,3-thiazol-2-yl}pyridine
CAS 672951-40-5C16H12Cl2N2O2S2
2-Hydroxy-5-(2-pyridin-3-yl-1,3-thiazol-4-yl)benzamide chemical structure, C15H11N3O2S, CAS 854135-27-6
2-Hydroxy-5-(2-pyridin-3-yl-1,3-thiazol-4-yl)benzamide
CAS 854135-27-6C15H11N3O2S
N,N-Diethyl-4-[2-(pyridin-3-yl)-1,3-thiazol-4-yl]benzene-1-sulfonamide chemical structure, C18H19N3O2S2, CAS 618063-18-6
N,N-Diethyl-4-[2-(pyridin-3-yl)-1,3-thiazol-4-yl]benzene-1-sulfonamide
CAS 618063-18-6C18H19N3O2S2
4-[2-(3-Pyridinyl)-4-thiazolyl]benzoic acid chemical structure, C15H10N2O2S, CAS 254911-29-0
4-[2-(3-Pyridinyl)-4-thiazolyl]benzoic acid
CAS 254911-29-0C15H10N2O2S
3-{4-[4-(Methylsulfonyl)phenyl]-1,3-thiazol-2-yl}pyridine chemical structure, C15H12N2O2S2, CAS 789483-49-4
3-{4-[4-(Methylsulfonyl)phenyl]-1,3-thiazol-2-yl}pyridine
CAS 789483-49-4C15H12N2O2S2