Murcko scaffold
Ring system with 5 rings and 23 atoms
32 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 23
- Chemicals
- 32
- With full pages
- 4
Scaffold SMILES
O=C(OCC1c2ccccc2-c2ccccc21)N1CC2CC2C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 32 of 32 chemicals
![(1S,2S,5R,6R)-6-[2-(tert-Butoxycarbonylamino)ethyl]-3-(9H-fluoren-9-ylmethoxycarbonyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid chemical structure, C28H32N2O6, CAS 903517-92-0](/s/BVZHOFGXGFIRTK-HTDNTCHWSA-N.svg)
(1S,2S,5R,6R)-6-[2-(tert-Butoxycarbonylamino)ethyl]-3-(9H-fluoren-9-ylmethoxycarbonyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid
CAS 903517-92-0C28H32N2O6
![Fmoc-trans-3-azabicyclo[3.1.0]hexane-2-carboxylicacid chemical structure, C21H19NO4, CAS 1219181-14-2](/s/BTOGCFAOJIQONJ-UHFFFAOYSA-N.svg)
Fmoc-trans-3-azabicyclo[3.1.0]hexane-2-carboxylicacid
CAS 1219181-14-2C21H19NO4
Fmoc-(R,S)-3,4-cis-methanoproline
CAS 1820598-59-1C21H19NO4
rac-(1R,2S,5S)-3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-azabicyclo(3.1.0)hexane-2-carboxylic acid
CAS 886846-30-6C21H19NO4
![(1S,2R,5R)-3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-azabicyclo[3.1.0]hexane-2-carboxylic acid chemical structure, C21H19NO4, CAS 2137087-47-7](/s/BTOGCFAOJIQONJ-OYYNGEPBSA-N.svg)
(1S,2R,5R)-3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-azabicyclo[3.1.0]hexane-2-carboxylic acid
CAS 2137087-47-7C21H19NO4
![(1R,2R,5S)-3-(9H-Fluoren-9-ylmethoxycarbonyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid chemical structure, C21H19NO4, CAS 2382052-27-7](/s/BTOGCFAOJIQONJ-QHLBDZCJSA-N.svg)
(1R,2R,5S)-3-(9H-Fluoren-9-ylmethoxycarbonyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid
CAS 2382052-27-7C21H19NO4
(1S,2S,5R)-3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-azabicyclo(3.1.0)hexane-2-carboxylic acid
CAS 854113-43-2C21H19NO4
![3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-azabicyclo[3.1.0]hexane-1-carboxylic acid chemical structure, C21H19NO4, CAS 1935920-81-2](/s/BYDTZRWAEAVMFE-UHFFFAOYSA-N.svg)
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
CAS 1935920-81-2C21H19NO4
![rac-(1R,5S)-3-{[(9H-fluoren-9-yl)methoxy]carbonyl}-5-(trifluoromethyl)-3-azabicyclo[3.1.0]hexane-1-carboxylic acid chemical structure, C22H18F3NO4, CAS 1992960-45-8](/s/ZIHZSZUZCSMEMN-NHCUHLMSSA-N.svg)
rac-(1R,5S)-3-{[(9H-fluoren-9-yl)methoxy]carbonyl}-5-(trifluoromethyl)-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
CAS 1992960-45-8C22H18F3NO4
(1R,5S,6R)-3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-azabicyclo(3.1.0)hexane-6-carboxylic acid
CAS 1932558-35-4C21H19NO4
![3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-azabicyclo[3.1.0]hexane-6-carboxylic acid chemical structure, C21H19NO4, CAS 1935126-50-3](/s/PUSKDCKSDXNANI-UHFFFAOYSA-N.svg)
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-azabicyclo[3.1.0]hexane-6-carboxylic acid
CAS 1935126-50-3C21H19NO4
rac-(1R,5S)-3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-azabicyclo(3.1.0)hexane-1-carboxylic acid
CAS 2138240-30-7C21H19NO4
![(1R,5R)-3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-azabicyclo[3.1.0]hexane-1-carboxylic acid chemical structure, C21H19NO4, CAS 2381048-87-7](/s/BYDTZRWAEAVMFE-ZSEKCTLFSA-N.svg)
(1R,5R)-3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
CAS 2381048-87-7C21H19NO4
![rac-(1R,5R)-3-{[(9H-fluoren-9-yl)methoxy]carbonyl}-5-methyl-3-azabicyclo[3.1.0]hexane-1-carboxylicacid,cis chemical structure, C22H21NO4, CAS 2416218-00-1](/s/LHHFGBVKANKUIB-YADHBBJMSA-N.svg)
rac-(1R,5R)-3-{[(9H-fluoren-9-yl)methoxy]carbonyl}-5-methyl-3-azabicyclo[3.1.0]hexane-1-carboxylicacid,cis
CAS 2416218-00-1C22H21NO4
![(1S,5S)-3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-azabicyclo[3.1.0]hexane-1-carboxylic acid chemical structure, C21H19NO4, CAS 2418594-18-8](/s/BYDTZRWAEAVMFE-LRTDBIEQSA-N.svg)
(1S,5S)-3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
CAS 2418594-18-8C21H19NO4
![(1R,2S,5S)-3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid chemical structure, C23H23NO4, CAS 2413059-77-3](/s/WHIBJXLGJGJCLQ-UFYCRDLUSA-N.svg)
(1R,2S,5S)-3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid
CAS 2413059-77-3C23H23NO4
![3-[(1R,5S,6R)-3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-azabicyclo[3.1.0]hexan-6-yl]prop-2-ynoic acid chemical structure, C23H19NO4, CAS 2757836-03-4](/s/CIQVKVWBPXZJHC-IHWFROFDSA-N.svg)
3-[(1R,5S,6R)-3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-azabicyclo[3.1.0]hexan-6-yl]prop-2-ynoic acid
CAS 2757836-03-4C23H19NO4
![3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6,6-difluoro-3-azabicyclo[3.1.0]hexane-1-carboxylic acid chemical structure, C21H17F2NO4, CAS 2580242-41-5](/s/DASBZWZLCFYTAM-UHFFFAOYSA-N.svg)
3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6,6-difluoro-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
CAS 2580242-41-5C21H17F2NO4
![(9H-Fluoren-9-yl)methyl 1-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate chemical structure, C21H21NO3, CAS 2300767-76-2](/s/CGBFQSLQXGPIDV-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl 1-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate
CAS 2300767-76-2C21H21NO3
![(9H-Fluoren-9-yl)methyl (1R,5S,6R)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate chemical structure, C21H21NO3, CAS 2763885-45-4](/s/ORIFCQZJPWGCQG-DFNIBXOVSA-N.svg)
(9H-Fluoren-9-yl)methyl (1R,5S,6R)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate
CAS 2763885-45-4C21H21NO3
![(9H-Fluoren-9-yl)methyl 1-hydroxy-3-azabicyclo[3.1.0]hexane-3-carboxylate chemical structure, C20H19NO3, CAS 2763912-55-4](/s/YSWPHKJYSRUNSS-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl 1-hydroxy-3-azabicyclo[3.1.0]hexane-3-carboxylate
CAS 2763912-55-4C20H19NO3
![rac-(9H-Fluoren-9-yl)methyl (1R,5R)-1-(hydroxymethyl)-5-methyl-3-azabicyclo[3.1.0]hexane-3-carboxylate chemical structure, C22H23NO3, CAS 2763924-43-0](/s/RUVVDWIUNCMJSH-YADHBBJMSA-N.svg)
rac-(9H-Fluoren-9-yl)methyl (1R,5R)-1-(hydroxymethyl)-5-methyl-3-azabicyclo[3.1.0]hexane-3-carboxylate
CAS 2763924-43-0C22H23NO3
![rac-(9H-Fluoren-9-yl)methyl (1R,5S)-1-(hydroxymethyl)-5-(trifluoromethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate chemical structure, C22H20F3NO3, CAS 2764007-46-5](/s/IVTNRHSVDYYPSB-NHCUHLMSSA-N.svg)
rac-(9H-Fluoren-9-yl)methyl (1R,5S)-1-(hydroxymethyl)-5-(trifluoromethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate
CAS 2764007-46-5C22H20F3NO3
![(9H-Fluoren-9-yl)methyl (1S,5S)-1-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate chemical structure, C21H21NO3, CAS 2763886-23-1](/s/CGBFQSLQXGPIDV-SZNDQCEHSA-N.svg)
(9H-Fluoren-9-yl)methyl (1S,5S)-1-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate
CAS 2763886-23-1C21H21NO3
- (9H-Fluoren-9-yl)methyl (1R,5R)-1-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate2763887-50-7C21H21NO3
- (9H-Fluoren-9-yl)methyl (1R)-1-ethynyl-3-azabicyclo[3.1.0]hexane-3-carboxylate2770475-12-0C22H19NO2
- (9H-Fluoren-9-yl)methyl (1R,5S,6R)-6-ethynyl-3-azabicyclo[3.1.0]hexane-3-carboxylate2770452-18-9C22H19NO2
- rac-2-[(1R,5S,6R)-3-{[(9H-fluoren-9-yl)methoxy]carbonyl}-3-azabicyclo[3.1.0]hexan-6-yl]acetic acid2919940-54-6C22H21NO4
- 3-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6,6-difluoro-3-azabicyclo[3.1.0]hexane-2-carboxylic acid2386649-38-1C21H17F2NO4
- 3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-6-fluoro-3-azabicyclo[3.1.0]hexane-6-carboxylic acid2988166-76-1C21H18FNO4
- rel-(1R,5S)-3-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid2321451-00-5C21H19NO4
- (1S,2S,5R,6R)-6-[(tert-Butoxycarbonylamino)methyl]-3-(9H-fluoren-9-ylmethoxycarbonyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid1061736-86-4C27H30N2O6