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Murcko scaffold

7-Ketopyrazolo(4,3-d)pyrimidine scaffold

68 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
68
With full pages
12
Scaffold SMILES

O=c1[nH]cnc2c[nH]nc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 7-Ketopyrazolo(4,3-d)pyrimidine page
Murcko scaffold O=c1[nH]cnc2c[nH]nc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 68 chemicals

6-Hydroxy-3-methyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one chemical structure, C6H6N4O2, CAS 28668-25-9
6-Hydroxy-3-methyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
CAS 28668-25-9C6H6N4O2
3,6-Dimethyl-2H-pyrazolo[4,3-d]pyrimidin-7-one chemical structure, C7H8N4O, CAS 60753-31-3
3,6-Dimethyl-2H-pyrazolo[4,3-d]pyrimidin-7-one
CAS 60753-31-3C7H8N4O
1H-Pyrazolo(4,3-d)pyrimidin-7(6H)-one, 6-isopentyl-3-methyl- chemical structure, C11H16N4O, CAS 80030-87-1
1H-Pyrazolo(4,3-d)pyrimidin-7(6H)-one, 6-isopentyl-3-methyl-
CAS 80030-87-1C11H16N4O
6-Butyl-3-methyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one chemical structure, C10H14N4O, CAS 80043-70-5
6-Butyl-3-methyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
CAS 80043-70-5C10H14N4O
5-(Chloromethyl)-1,3-dimethyl-6-propan-2-ylpyrazolo[4,5-d]pyrimidin-7-one chemical structure, C11H15ClN4O, CAS 1092287-22-3
5-(Chloromethyl)-1,3-dimethyl-6-propan-2-ylpyrazolo[4,5-d]pyrimidin-7-one
CAS 1092287-22-3C11H15ClN4O
5-Chloro-1,3-dimethyl-6-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one chemical structure, C10H13ClN4O, CAS 1365964-11-9
5-Chloro-1,3-dimethyl-6-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
CAS 1365964-11-9C10H13ClN4O
3-Bromo-6-methyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one chemical structure, C6H5BrN4O, CAS 1784050-78-7
3-Bromo-6-methyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
CAS 1784050-78-7C6H5BrN4O
5-Chloro-1,3,6-trimethyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one chemical structure, C8H9ClN4O, CAS 1795186-69-4
5-Chloro-1,3,6-trimethyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one
CAS 1795186-69-4C8H9ClN4O
3-Methyl-5-(methylsulfanyl)-2,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one chemical structure, C7H8N4OS, CAS 28745-13-3
3-Methyl-5-(methylsulfanyl)-2,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
CAS 28745-13-3C7H8N4OS
1,6-Dihydro-3-methyl-7H-pyrazolo[4,3-d]pyrimidin-7-one chemical structure, C6H6N4O, CAS 5399-94-0
1,6-Dihydro-3-methyl-7H-pyrazolo[4,3-d]pyrimidin-7-one
CAS 5399-94-0C6H6N4O
1-Methyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one chemical structure, C6H6N4O, CAS 314021-93-7
1-Methyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one
CAS 314021-93-7C6H6N4O
5-Amino-7-oxo-1,6-dihydro-pyrazolo[4,3-d]pyrimidine chemical structure, C5H5N5O, CAS 41535-76-6
5-Amino-7-oxo-1,6-dihydro-pyrazolo[4,3-d]pyrimidine
CAS 41535-76-6C5H5N5O
7-Ketopyrazolo(4,3-d)pyrimidine chemical structure, C5H4N4O, CAS 13877-55-9
7-Ketopyrazolo(4,3-d)pyrimidine
CAS 13877-55-9C5H4N4O
5-Ethyl-1-methyl-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-7-one chemical structure, C11H16N4O, CAS 447417-30-3
5-Ethyl-1-methyl-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-7-one
CAS 447417-30-3C11H16N4O
3-Iodo-1H,4H,7H-pyrazolo[4,3-d]pyrimidin-7-one chemical structure, C5H3IN4O, CAS 142189-88-6
3-Iodo-1H,4H,7H-pyrazolo[4,3-d]pyrimidin-7-one
CAS 142189-88-6C5H3IN4O
5-Methyl-1H-pyrazolo[4,3-d]pyrimidin-7-ol chemical structure, C6H6N4O, CAS 55904-62-6
5-Methyl-1H-pyrazolo[4,3-d]pyrimidin-7-ol
CAS 55904-62-6C6H6N4O
1-Ethyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one chemical structure, C7H8N4O, CAS 674788-53-5
1-Ethyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
CAS 674788-53-5C7H8N4O
1,3-Dimethyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one chemical structure, C7H8N4O, CAS 51222-27-6
1,3-Dimethyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one
CAS 51222-27-6C7H8N4O
2-Ethyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one chemical structure, C7H8N4O, CAS 923283-59-4
2-Ethyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
CAS 923283-59-4C7H8N4O
1,3,5-Trimethyl-1H,6H,7H-pyrazolo(4,3-d)pyrimidin-7-one chemical structure, C8H10N4O, CAS 59023-33-5
1,3,5-Trimethyl-1H,6H,7H-pyrazolo(4,3-d)pyrimidin-7-one
CAS 59023-33-5C8H10N4O
7H-Pyrazolo[4,3-D]pyrimidin-7-one, 5-ethyl-1,4-dihydro-3-(1-methylethyl)- chemical structure, C10H14N4O, CAS 521297-23-4
7H-Pyrazolo[4,3-D]pyrimidin-7-one, 5-ethyl-1,4-dihydro-3-(1-methylethyl)-
CAS 521297-23-4C10H14N4O
3-Bromo-1H,6H,7H-pyrazolo(4,3-d)pyrimidin-7-one chemical structure, C5H3BrN4O, CAS 20419-67-4
3-Bromo-1H,6H,7H-pyrazolo(4,3-d)pyrimidin-7-one
CAS 20419-67-4C5H3BrN4O
5-Chloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one chemical structure, C6H5ClN4O, CAS 1211533-31-1
5-Chloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
CAS 1211533-31-1C6H5ClN4O
7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,6-dihydro-3-(1-methylethyl)-5-(methylthio)- chemical structure, C9H12N4OS, CAS 1289139-29-2
7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,6-dihydro-3-(1-methylethyl)-5-(methylthio)-
CAS 1289139-29-2C9H12N4OS