Murcko scaffold
Thieno[2,3-d]pyrimidine-2,4-diol scaffold
55 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 11
- Chemicals
- 55
- With full pages
- 4
Scaffold SMILES
O=c1[nH]c(=O)c2ccsc2[nH]1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1[nH]c(=O)c2ccsc2[nH]1](/scaffold/JGOOQALRLGHKIY-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 55 chemicals
![5-Methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione chemical structure, C7H6N2O2S, CAS 75860-79-6](/s/GKMPAIVLIOXQSS-UHFFFAOYSA-N.svg)
5-Methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
CAS 75860-79-6C7H6N2O2S
![3-Hydroxy-1H-thieno[2,3-d]pyrimidine-2,4-dione chemical structure, C6H4N2O3S, CAS 53229-49-5](/s/NNWNTVVLCCOLEQ-UHFFFAOYSA-N.svg)
3-Hydroxy-1H-thieno[2,3-d]pyrimidine-2,4-dione
CAS 53229-49-5C6H4N2O3S
![5,6-Dimethylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione chemical structure, C8H8N2O2S, CAS 35970-82-2](/s/DBDWJBNPOZKDOJ-UHFFFAOYSA-N.svg)
5,6-Dimethylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
CAS 35970-82-2C8H8N2O2S
![3,5,6-Trimethylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione chemical structure, C9H10N2O2S, CAS 35970-83-3](/s/HKTADEQKOXKZBH-UHFFFAOYSA-N.svg)
3,5,6-Trimethylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
CAS 35970-83-3C9H10N2O2S
Thieno(2,3-d)pyrimidine-1(2H)-acetic acid, 3,4-dihydro-3-butyl-5,6-dimethyl-2,4-dioxo-
CAS 203808-43-9C14H18N2O4S
![1,2,3,4-Tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxothieno[2,3-d]pyrimidine-5-carboxylic acid chemical structure, C12H14N2O4S, CAS 259862-10-7](/s/YLIGFLLLNZULKU-UHFFFAOYSA-N.svg)
1,2,3,4-Tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxothieno[2,3-d]pyrimidine-5-carboxylic acid
CAS 259862-10-7C12H14N2O4S
![Methyl 1-isobutyl-3,6-dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-5-carboxylate chemical structure, C14H18N2O4S, CAS 491613-98-0](/s/ZOZLIRDDECXJGM-UHFFFAOYSA-N.svg)
Methyl 1-isobutyl-3,6-dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-5-carboxylate
CAS 491613-98-0C14H18N2O4S
![Ethyl 3-methyl-1-(2-methylpropyl)-2,4-dioxo-1,2,3,4-tetrahydro-thieno[2,3-d]pyrimidine-5-carboxylate chemical structure, C14H18N2O4S, CAS 259862-09-4](/s/QFPLBRLCXPFSHN-UHFFFAOYSA-N.svg)
Ethyl 3-methyl-1-(2-methylpropyl)-2,4-dioxo-1,2,3,4-tetrahydro-thieno[2,3-d]pyrimidine-5-carboxylate
CAS 259862-09-4C14H18N2O4S
![1-Methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxylic acid chemical structure, C8H6N2O4S, CAS 448965-10-4](/s/MIHDYSQCLUGWGZ-UHFFFAOYSA-N.svg)
1-Methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxylic acid
CAS 448965-10-4C8H6N2O4S
![Thieno[2,3-d]pyrimidine-2,4-diol chemical structure, C6H4N2O2S, CAS 18740-38-0](/s/JGOOQALRLGHKIY-UHFFFAOYSA-N.svg)
Thieno[2,3-d]pyrimidine-2,4-diol
CAS 18740-38-0C6H4N2O2S
![3-Amino-5,6-dimethylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione chemical structure, C8H9N3O2S, CAS 62349-28-4](/s/LDLXRHZSTDUWOD-UHFFFAOYSA-N.svg)
3-Amino-5,6-dimethylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
CAS 62349-28-4C8H9N3O2S
![6-Methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione chemical structure, C7H6N2O2S, CAS 76872-71-4](/s/OUUVFLQOPRMEAA-UHFFFAOYSA-N.svg)
6-Methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
CAS 76872-71-4C7H6N2O2S
![Ethyl 5-amino-1,3-dimethyl-2,4-dioxo-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-6-carboxylate chemical structure, C11H13N3O4S, CAS 129177-36-2](/s/YESXMEATWOIPCS-UHFFFAOYSA-N.svg)
Ethyl 5-amino-1,3-dimethyl-2,4-dioxo-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-6-carboxylate
CAS 129177-36-2C11H13N3O4S
![1,3-Dimethyl-2,4-dioxo-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-6-carboxylic acid chemical structure, C9H8N2O4S, CAS 129177-39-5](/s/YSGDONMZXJIIQA-UHFFFAOYSA-N.svg)
1,3-Dimethyl-2,4-dioxo-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-6-carboxylic acid
CAS 129177-39-5C9H8N2O4S
![3-Methyl-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione chemical structure, C7H6N2O2S, CAS 75860-86-5](/s/OTNVPPORAQUGQB-UHFFFAOYSA-N.svg)
3-Methyl-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione
CAS 75860-86-5C7H6N2O2S
![6-Bromo-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione chemical structure, C11H13BrN2O2S, CAS 259862-18-5](/s/KLBJOSBKQSUDAO-UHFFFAOYSA-N.svg)
6-Bromo-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
CAS 259862-18-5C11H13BrN2O2S
![Ethyl 1-isopropyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-5-carboxylate chemical structure, C13H16N2O4S, CAS 496792-40-6](/s/BZICWDDODOYIFS-UHFFFAOYSA-N.svg)
Ethyl 1-isopropyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-5-carboxylate
CAS 496792-40-6C13H16N2O4S
![Methyl 6-bromomethyl-1-isobutyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-5-carboxylate chemical structure, C14H17BrN2O4S, CAS 491614-00-7](/s/FAFMDAMSLFFIFX-UHFFFAOYSA-N.svg)
Methyl 6-bromomethyl-1-isobutyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-5-carboxylate
CAS 491614-00-7C14H17BrN2O4S
![5-Amino-1,3-dimethyl-2,4-dioxo-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-6-carboxylic acid chemical structure, C9H9N3O4S, CAS 926259-36-1](/s/WODYJXPBVPWLPE-UHFFFAOYSA-N.svg)
5-Amino-1,3-dimethyl-2,4-dioxo-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-6-carboxylic acid
CAS 926259-36-1C9H9N3O4S
Methyl 1-isopropyl-3,6-dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno(2,3-d)pyrimidine-5-carboxylate
CAS 491614-26-7C13H16N2O4S
![3,5-Dimethylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione chemical structure, C8H8N2O2S, CAS 64572-03-8](/s/RDMCECHQIVHPLV-UHFFFAOYSA-N.svg)
3,5-Dimethylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
CAS 64572-03-8C8H8N2O2S
![N-Isobutyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide chemical structure, C13H17N3O3S, CAS 946257-28-9](/s/OGCVWHVCRWTWBK-UHFFFAOYSA-N.svg)
N-Isobutyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide
CAS 946257-28-9C13H17N3O3S
![N-(2-Hydroxyethyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide chemical structure, C11H13N3O4S, CAS 946257-49-4](/s/ZMEOSPADPDOFSO-UHFFFAOYSA-N.svg)
N-(2-Hydroxyethyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide
CAS 946257-49-4C11H13N3O4S
![N,1,3-trimethyl-2,4-dioxo-N-(propan-2-yl)-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-6-carboxamide chemical structure, C13H17N3O3S, CAS 946335-47-3](/s/APCPEJUWAUTJNR-UHFFFAOYSA-N.svg)
N,1,3-trimethyl-2,4-dioxo-N-(propan-2-yl)-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-6-carboxamide
CAS 946335-47-3C13H17N3O3S
- N-(4-Hydroxybutyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide946207-13-2C13H17N3O4S
- N-(2-Hydroxypropyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide946335-24-6C12H15N3O4S
- N-(2,3-Dihydroxypropyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide946257-43-8C12H15N3O5S
- N-(1-Methoxypropan-2-yl)-1,3-dimethyl-2,4-dioxo-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-6-carboxamide946207-07-4C13H17N3O4S
- 3-Hydroxy-5-methyl-1H-thieno[2,3-d]pyrimidine-2,4-dione824983-80-4C7H6N2O3S
- 3-Hydroxy-1,5-dimethylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione824983-86-0C8H8N2O3S
- Ethyl 2-{6-bromo-1-methyl-2,4-dioxo-1H,2H,3H,4H-thieno[2,3-d]pyrimidin-3-yl}acetate1263281-68-0C11H11BrN2O4S
- Ethyl 2-{5-bromo-1-methyl-2,4-dioxo-1H,2H,3H,4H-thieno[2,3-d]pyrimidin-3-yl}acetate1263282-22-9C11H11BrN2O4S
- 5-(Trifluoromethyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione1265593-58-5C7H3F3N2O2S
- 6-Ethyl-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione502649-08-3C8H8N2O2S
- Methyl 6-(bromomethyl)-1-isopropyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-5-carboxylate491614-28-9C13H15BrN2O4S
- 6-Propylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione902765-59-7C9H10N2O2S
- 6-(1-Methylethyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione902765-67-7C9H10N2O2S
- 2-(1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-5-yl)acetic acid1246761-51-2C10H10N2O4S
- 6-Butyl-3-(3-hydroxypropyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione1369338-94-2C13H18N2O3S
- tert-Butyl 2-methyl-2-(5-methyl-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)propanoate1434643-28-3C15H20N2O4S
- 3-(1-(tert-Butoxy)-2-methyl-1-oxopropan-2-yl)-5-methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxylic acid1434643-23-8C16H20N2O6S
- Thieno[2,3-d]pyrimidine-3(2H)-acetic acid, 6-(ethoxycarbonyl)-1,4-dihydro-alpha,alpha,5-trimethyl-2,4-dioxo-, 1,1-dimethylethyl ester1434643-18-1C18H24N2O6S
- tert-Butyl 2-(6-bromo-5-methyl-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)-2-methylpropanoate1434643-33-0C15H19BrN2O4S
- 2-(6-Bromo-5-methyl-2,4-dioxo-1,2-dihydrothieno[2,3-d]pyrimidin-3(4H)-yl)-2-methylpropanoic acid1434651-13-4C11H11BrN2O4S
- 2-(3,5,6-Trimethyl-2,4-dioxo-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl)acetic acid1707399-10-7C11H12N2O4S
- 3-(3-Aminopropyl)-6-methyl-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione hydrochloride2109294-30-4C10H14ClN3O2S
- Methyl 5-amino-1,3-dimethyl-2,4-dioxo-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-6-carboxylate1909316-25-1C10H11N3O4S
- 6-Bromothieno[2,3-d]pyrimidine-2,4(1H,3H)-dione2169589-51-7C6H3BrN2O2S
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