Murcko scaffold
Ring system with 2 rings and 18 atoms
10 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 18
- Chemicals
- 10
- With full pages
- 1
Scaffold SMILES
O=C(CCC1CCCCC1)OCc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 10 of 10 chemicals
(R)-3-Cyclohexyl-2-hydroxypropionic acid benzyl ester
CAS 161313-45-7C16H22O3
Benzyl (R)-2-amino-3-cyclohexylpropanoate
CAS 203732-78-9C16H23NO2
Benzyl 2-amino-3-cyclohexylpropanoate
CAS 1869101-55-2C16H23NO2
Benzyl (2S)-3-cyclohexyl-2-hydroxy-propanoate
CAS 140372-02-7C16H22O3
Benzyl (S)-2-amino-3-cyclohexylpropanoate
CAS 139397-45-8C16H23NO2
H-L-Cha-OBzl*HCl
CAS 138022-95-4C16H24ClNO2
Phenylmethyl ss-hydroxycyclohexanepropanoate
CAS 250221-31-9C16H22O3
Cyclohexanepropanoic acid, alpha-amino-, phenylmethyl ester, hydrochloride (1:1), (alphaR)-
CAS 266690-58-8C16H24ClNO2
Benzyl (2S)-2-amino-3-(4,4-difluorocyclohexyl)propanoate
CAS 1258075-91-0C16H21F2NO2
(R)-1-(Benzyloxycarbonyl)-2-cyclohexylethylphosphinic acid
CAS 108327-25-9C16H22O4P+
Related scaffolds
Same ring framework with different atoms or bond orders
S=C(NN=Cc1ccccc1)Nc1ccccc1105 chemicals
S=C(NCCc1ccccc1)Nc1ccccc160 chemicals
c1ccc(CCNCCc2ccccc2)cc158 chemicals
O=C(COc1ccccc1)NCc1ccccc146 chemicals
O=C(NCCOc1ccccc1)c1ccccc146 chemicals
O=C(C=Cc1ccccc1)NCc1ccccc143 chemicals
c1ccc(OCCCOc2ccccc2)cc141 chemicals
O=C(CC(=O)Nc1ccccc1)Nc1ccccc137 chemicals
O=C(CNS(=O)(=O)c1ccccc1)Nc1ccccc136 chemicals
O=C(CSCc1ccccc1)Nc1ccccc133 chemicals
O=C(Cc1ccccc1)NCCc1ccccc132 chemicals
O=C(CNCc1ccccc1)Nc1ccccc131 chemicals