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Murcko scaffold

Ring system with 3 rings and 19 atoms

26 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
26
With full pages
10
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCC2(CC1)OCCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)N1CCC2(CC1)OCCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

8-Tosyl-1,4-dioxa-8-azaspiro[4.5]decane chemical structure, C14H19NO4S, CAS 853751-19-6
8-Tosyl-1,4-dioxa-8-azaspiro[4.5]decane
CAS 853751-19-6C14H19NO4S
8-((4-Chlorophenyl)sulfonyl)-1,4-dioxa-8-azaspiro(4.5)decane chemical structure, C13H16ClNO4S, CAS 853751-20-9
8-((4-Chlorophenyl)sulfonyl)-1,4-dioxa-8-azaspiro(4.5)decane
CAS 853751-20-9C13H16ClNO4S
8-((4-Bromophenyl)sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane chemical structure, C13H16BrNO4S, CAS 849532-19-0
8-((4-Bromophenyl)sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane
CAS 849532-19-0C13H16BrNO4S
N-[4-(1,4-Dioxa-8-azaspiro[4.5]dec-8-ylsulfonyl)phenyl]acetamide chemical structure, C15H20N2O5S, CAS 853751-22-1
N-[4-(1,4-Dioxa-8-azaspiro[4.5]dec-8-ylsulfonyl)phenyl]acetamide
CAS 853751-22-1C15H20N2O5S
8-(4-Propan-2-ylphenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane chemical structure, C16H23NO4S, CAS 888191-32-0
8-(4-Propan-2-ylphenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
CAS 888191-32-0C16H23NO4S
8-(3,4-Difluorophenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane chemical structure, C13H15F2NO4S, CAS 888193-76-8
8-(3,4-Difluorophenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
CAS 888193-76-8C13H15F2NO4S
8-(4-Butylphenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane chemical structure, C17H25NO4S, CAS 888191-26-2
8-(4-Butylphenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
CAS 888191-26-2C17H25NO4S
8-(2,5-Difluorophenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane chemical structure, C13H15F2NO4S, CAS 888193-82-6
8-(2,5-Difluorophenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
CAS 888193-82-6C13H15F2NO4S
8-(2,3,4,5,6-Pentamethylphenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane chemical structure, C18H27NO4S, CAS 888194-36-3
8-(2,3,4,5,6-Pentamethylphenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
CAS 888194-36-3C18H27NO4S
8-(2,4-Dimethylphenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane chemical structure, C15H21NO4S, CAS 888194-06-7
8-(2,4-Dimethylphenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
CAS 888194-06-7C15H21NO4S
8-[(2,4,5-Trichlorophenyl)sulfonyl]-1,4-dioxa-8-azaspiro[4.5]decane chemical structure, C13H14Cl3NO4S, CAS 669709-50-6
8-[(2,4,5-Trichlorophenyl)sulfonyl]-1,4-dioxa-8-azaspiro[4.5]decane
CAS 669709-50-6C13H14Cl3NO4S
8-[(4-Ethoxyphenyl)sulfonyl]-1,4-dioxa-8-azaspiro[4.5]decane chemical structure, C15H21NO5S, CAS 847473-72-7
8-[(4-Ethoxyphenyl)sulfonyl]-1,4-dioxa-8-azaspiro[4.5]decane
CAS 847473-72-7C15H21NO5S
4-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)phenylboronic acid chemical structure, C13H18BNO6S, CAS 914610-70-1
4-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)phenylboronic acid
CAS 914610-70-1C13H18BNO6S
8-((3-Bromophenyl)sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane chemical structure, C13H16BrNO4S, CAS 1137509-73-9
8-((3-Bromophenyl)sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane
CAS 1137509-73-9C13H16BrNO4S
8-((5-Bromo-2-methoxyphenyl)sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane chemical structure, C14H18BrNO5S, CAS 1296556-64-3
8-((5-Bromo-2-methoxyphenyl)sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane
CAS 1296556-64-3C14H18BrNO5S
8-((3-Bromo-4-methoxyphenyl)sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane chemical structure, C14H18BrNO5S, CAS 1704074-58-7
8-((3-Bromo-4-methoxyphenyl)sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane
CAS 1704074-58-7C14H18BrNO5S
4-(1,4-Dioxa-8-azaspiro[4.5]decane-8-sulfonyl)benzene-1-sulfonamide chemical structure, C13H18N2O6S2, CAS 55619-38-0
4-(1,4-Dioxa-8-azaspiro[4.5]decane-8-sulfonyl)benzene-1-sulfonamide
CAS 55619-38-0C13H18N2O6S2
8-((5-Bromo-2-(trifluoromethoxy)phenyl)sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane chemical structure, C14H15BrF3NO5S, CAS 1704065-50-8
8-((5-Bromo-2-(trifluoromethoxy)phenyl)sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane
CAS 1704065-50-8C14H15BrF3NO5S
8-((2-Bromo-4,5-difluorophenyl)sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane chemical structure, C13H14BrF2NO4S, CAS 1704065-68-8
8-((2-Bromo-4,5-difluorophenyl)sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane
CAS 1704065-68-8C13H14BrF2NO4S
(3-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)-4-(trifluoromethoxy)phenyl)boronic acid chemical structure, C14H17BF3NO7S, CAS 1704069-26-0
(3-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)-4-(trifluoromethoxy)phenyl)boronic acid
CAS 1704069-26-0C14H17BF3NO7S
(3-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)phenyl)boronic acid chemical structure, C13H18BNO6S, CAS 1704073-79-9
(3-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)phenyl)boronic acid
CAS 1704073-79-9C13H18BNO6S
(2-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)-4,5-difluorophenyl)boronic acid chemical structure, C13H16BF2NO6S, CAS 1704074-09-8
(2-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)-4,5-difluorophenyl)boronic acid
CAS 1704074-09-8C13H16BF2NO6S
(5-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)-2-methoxyphenyl)boronic acid chemical structure, C14H20BNO7S, CAS 1704095-38-4
(5-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)-2-methoxyphenyl)boronic acid
CAS 1704095-38-4C14H20BNO7S
(3-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)-4-methoxyphenyl)boronic acid chemical structure, C14H20BNO7S, CAS 1704096-51-4
(3-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)-4-methoxyphenyl)boronic acid
CAS 1704096-51-4C14H20BNO7S