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Murcko scaffold

4-(4-Benzyl-piperazin-1-yl)-1H-indole scaffold

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
12
With full pages
3
Scaffold SMILES

c1ccc(CN2CCN(c3cccc4[nH]ccc34)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(4-Benzyl-piperazin-1-yl)-1H-indole page
Murcko scaffold c1ccc(CN2CCN(c3cccc4[nH]ccc34)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

4-(4-Benzylpiperazino)-1H-indole dihydrochloride monohydrate chemical structure, C19H25Cl2N3O, CAS 690632-86-1
4-(4-Benzylpiperazino)-1H-indole dihydrochloride monohydrate
CAS 690632-86-1C19H25Cl2N3O
4-(4-Benzyl-piperazin-1-yl)-1H-indole chemical structure, C19H21N3, CAS 218933-36-9
4-(4-Benzyl-piperazin-1-yl)-1H-indole
CAS 218933-36-9C19H21N3
4-[4-[(2-Chlorophenyl)methyl]-1-piperazinyl]-1H-indole chemical structure, C19H20ClN3, CAS 334974-31-1
4-[4-[(2-Chlorophenyl)methyl]-1-piperazinyl]-1H-indole
CAS 334974-31-1C19H20ClN3
4-[4-[(2,4-Dichlorophenyl)methyl]piperazin-1-yl]-1H-indole chemical structure, C19H19Cl2N3, CAS 334974-33-3
4-[4-[(2,4-Dichlorophenyl)methyl]piperazin-1-yl]-1H-indole
CAS 334974-33-3C19H19Cl2N3
4-[4-[(3-Nitrophenyl)methyl]piperazin-1-yl]-1H-indole chemical structure, C19H20N4O2, CAS 334974-35-5
4-[4-[(3-Nitrophenyl)methyl]piperazin-1-yl]-1H-indole
CAS 334974-35-5C19H20N4O2
4-(4-(4-Methylbenzyl)piperazin-1-yl)-1H-indole chemical structure, C20H23N3, CAS 334974-36-6
4-(4-(4-Methylbenzyl)piperazin-1-yl)-1H-indole
CAS 334974-36-6C20H23N3
1H-Indole,4-[4-[(2-fluorophenyl)methyl]-1-piperazinyl]-,dihydrochloride chemical structure, C19H22Cl2FN3, CAS 334974-37-7
1H-Indole,4-[4-[(2-fluorophenyl)methyl]-1-piperazinyl]-,dihydrochloride
CAS 334974-37-7C19H22Cl2FN3
1H-Indole,4-[4-[(3,4-dichlorophenyl)methyl]-1-piperazinyl]-,dihydrochloride chemical structure, C19H21Cl4N3, CAS 334974-44-6
1H-Indole,4-[4-[(3,4-dichlorophenyl)methyl]-1-piperazinyl]-,dihydrochloride
CAS 334974-44-6C19H21Cl4N3
4-(4-Benzylpiperazin-1-yl)-1H-indole dihydrochloride chemical structure, C19H23Cl2N3, CAS 309755-88-2
4-(4-Benzylpiperazin-1-yl)-1H-indole dihydrochloride
CAS 309755-88-2C19H23Cl2N3
tert-Butyl 4-((4-(1H-indol-4-yl)piperazin-1-yl)methyl)benzoate chemical structure, C24H29N3O2, CAS 1044764-12-6
tert-Butyl 4-((4-(1H-indol-4-yl)piperazin-1-yl)methyl)benzoate
CAS 1044764-12-6C24H29N3O2
5-HT7 agonist 2 chemical structure, C23H29N3O, CAS 1206846-61-8
5-HT7 agonist 2
CAS 1206846-61-8C23H29N3O
4-(4-Benzylpiperazin-1-yl)-5-fluoro-1H-indole chemical structure, C19H20FN3, CAS 1171918-02-7
4-(4-Benzylpiperazin-1-yl)-5-fluoro-1H-indole
CAS 1171918-02-7C19H20FN3