CompoundList
Sign in
Murcko scaffold

6-(4-Benzylpiperazin-1-yl)-7H-purine scaffold

20 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
20
With full pages
1
Scaffold SMILES

c1ccc(CN2CCN(c3ncnc4nc[nH]c34)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-(4-Benzylpiperazin-1-yl)-7H-purine page
Murcko scaffold c1ccc(CN2CCN(c3ncnc4nc[nH]c34)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

6-(4-Benzylpiperazin-1-yl)-7H-purine chemical structure, C16H18N6, CAS 537667-20-2
6-(4-Benzylpiperazin-1-yl)-7H-purine
CAS 537667-20-2C16H18N6
4-{[4-(9-Methyl-9H-purin-6-yl)piperazin-1-yl]methyl}benzonitrile chemical structure, C18H19N7, CAS 2548992-53-4
4-{[4-(9-Methyl-9H-purin-6-yl)piperazin-1-yl]methyl}benzonitrile
CAS 2548992-53-4C18H19N7
4-{[4-(7-Methyl-7H-purin-6-yl)piperazin-1-yl]methyl}benzonitrile chemical structure, C18H19N7, CAS 2549001-38-7
4-{[4-(7-Methyl-7H-purin-6-yl)piperazin-1-yl]methyl}benzonitrile
CAS 2549001-38-7C18H19N7
6-(4-Benzylpiperazin-1-yl)-9-(2-methoxyethyl)-9H-purine chemical structure, C19H24N6O, CAS 2640950-02-1
6-(4-Benzylpiperazin-1-yl)-9-(2-methoxyethyl)-9H-purine
CAS 2640950-02-1C19H24N6O
4-({4-[9-(2-Methoxyethyl)-9H-purin-6-yl]piperazin-1-yl}methyl)benzonitrile chemical structure, C20H23N7O, CAS 2741957-34-4
4-({4-[9-(2-Methoxyethyl)-9H-purin-6-yl]piperazin-1-yl}methyl)benzonitrile
CAS 2741957-34-4C20H23N7O
4-{[4-(9-Ethyl-9H-purin-6-yl)piperazin-1-yl]methyl}benzonitrile chemical structure, C19H21N7, CAS 2640903-23-5
4-{[4-(9-Ethyl-9H-purin-6-yl)piperazin-1-yl]methyl}benzonitrile
CAS 2640903-23-5C19H21N7
9-Ethyl-6-{4-[(2-fluorophenyl)methyl]piperazin-1-yl}-9H-purine chemical structure, C18H21FN6, CAS 2741931-08-6
9-Ethyl-6-{4-[(2-fluorophenyl)methyl]piperazin-1-yl}-9H-purine
CAS 2741931-08-6C18H21FN6
6-{4-[(2,4-Difluorophenyl)methyl]piperazin-1-yl}-9-ethyl-9H-purine chemical structure, C18H20F2N6, CAS 2741936-63-8
6-{4-[(2,4-Difluorophenyl)methyl]piperazin-1-yl}-9-ethyl-9H-purine
CAS 2741936-63-8C18H20F2N6
6-{4-[(2-Chloro-6-fluorophenyl)methyl]piperazin-1-yl}-9-ethyl-9H-purine chemical structure, C18H20ClFN6, CAS 2742040-66-8
6-{4-[(2-Chloro-6-fluorophenyl)methyl]piperazin-1-yl}-9-ethyl-9H-purine
CAS 2742040-66-8C18H20ClFN6
9-Ethyl-6-(4-{[2-(trifluoromethyl)phenyl]methyl}piperazin-1-yl)-9H-purine chemical structure, C19H21F3N6, CAS 2741926-22-5
9-Ethyl-6-(4-{[2-(trifluoromethyl)phenyl]methyl}piperazin-1-yl)-9H-purine
CAS 2741926-22-5C19H21F3N6
6-{4-[(2,4-Difluorophenyl)methyl]-3-methylpiperazin-1-yl}-9-methyl-9H-purine chemical structure, C18H20F2N6, CAS 2742005-91-8
6-{4-[(2,4-Difluorophenyl)methyl]-3-methylpiperazin-1-yl}-9-methyl-9H-purine
CAS 2742005-91-8C18H20F2N6
6-{4-[(2,4-Difluorophenyl)methyl]-3-methylpiperazin-1-yl}-7-methyl-7H-purine chemical structure, C18H20F2N6, CAS 2741942-30-1
6-{4-[(2,4-Difluorophenyl)methyl]-3-methylpiperazin-1-yl}-7-methyl-7H-purine
CAS 2741942-30-1C18H20F2N6
6-{4-[(3,5-Difluorophenyl)methyl]-3-methylpiperazin-1-yl}-9-methyl-9H-purine chemical structure, C18H20F2N6, CAS 2741948-88-7
6-{4-[(3,5-Difluorophenyl)methyl]-3-methylpiperazin-1-yl}-9-methyl-9H-purine
CAS 2741948-88-7C18H20F2N6
6-{4-[(3,5-Difluorophenyl)methyl]-3-methylpiperazin-1-yl}-7-methyl-7H-purine chemical structure, C18H20F2N6, CAS 2742041-13-8
6-{4-[(3,5-Difluorophenyl)methyl]-3-methylpiperazin-1-yl}-7-methyl-7H-purine
CAS 2742041-13-8C18H20F2N6
6-{4-[(2,4-Difluorophenyl)methyl]-3-methylpiperazin-1-yl}-9H-purine chemical structure, C17H18F2N6, CAS 2741940-06-5
6-{4-[(2,4-Difluorophenyl)methyl]-3-methylpiperazin-1-yl}-9H-purine
CAS 2741940-06-5C17H18F2N6
6-{4-[(3,5-Difluorophenyl)methyl]-3-methylpiperazin-1-yl}-9H-purine chemical structure, C17H18F2N6, CAS 2741931-50-8
6-{4-[(3,5-Difluorophenyl)methyl]-3-methylpiperazin-1-yl}-9H-purine
CAS 2741931-50-8C17H18F2N6
6-(4-{[2-(Trifluoromethyl)phenyl]methyl}piperazin-1-yl)-9H-purine chemical structure, C17H17F3N6, CAS 2770603-80-8
6-(4-{[2-(Trifluoromethyl)phenyl]methyl}piperazin-1-yl)-9H-purine
CAS 2770603-80-8C17H17F3N6
6-{4-[(3-Fluoro-4-methoxyphenyl)methyl]-3-methylpiperazin-1-yl}-9-methyl-9H-purine chemical structure, C19H23FN6O, CAS 2877691-60-4
6-{4-[(3-Fluoro-4-methoxyphenyl)methyl]-3-methylpiperazin-1-yl}-9-methyl-9H-purine
CAS 2877691-60-4C19H23FN6O
6-{4-[(3-Fluoro-4-methoxyphenyl)methyl]-3-methylpiperazin-1-yl}-9H-purine chemical structure, C18H21FN6O, CAS 2877708-29-5
6-{4-[(3-Fluoro-4-methoxyphenyl)methyl]-3-methylpiperazin-1-yl}-9H-purine
CAS 2877708-29-5C18H21FN6O
6-(4-Benzylpiperazin-1-yl)-9-ethyl-9H-purine chemical structure, C18H22N6, CAS 2877707-68-9
6-(4-Benzylpiperazin-1-yl)-9-ethyl-9H-purine
CAS 2877707-68-9C18H22N6