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Murcko scaffold

4-[4-(Phenylsulfonyl)-1-piperazinyl]thieno[2,3-d]pyrimidine scaffold

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
5
With full pages
2
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCN(c2ncnc3sccc23)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-[4-(Phenylsulfonyl)-1-piperazinyl]thieno[2,3-d]pyrimidine page
Murcko scaffold O=S(=O)(c1ccccc1)N1CCN(c2ncnc3sccc23)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

4-[4-(2,5-Dimethylphenyl)sulfonylpiperazin-1-yl]thieno[2,3-d]pyrimidine chemical structure, C18H20N4O2S2, CAS 744269-45-2
4-[4-(2,5-Dimethylphenyl)sulfonylpiperazin-1-yl]thieno[2,3-d]pyrimidine
CAS 744269-45-2C18H20N4O2S2
4-[4-[2-(Trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]thieno[2,3-d]pyrimidine chemical structure, C17H15F3N4O2S2, CAS 745022-96-2
4-[4-[2-(Trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]thieno[2,3-d]pyrimidine
CAS 745022-96-2C17H15F3N4O2S2
Ethyl 4-[4-(benzenesulfonyl)piperazin-1-yl]-2,5-dimethylthieno[2,3-d]pyrimidine-6-carboxylate chemical structure, C21H24N4O4S2, CAS 790724-95-7
Ethyl 4-[4-(benzenesulfonyl)piperazin-1-yl]-2,5-dimethylthieno[2,3-d]pyrimidine-6-carboxylate
CAS 790724-95-7C21H24N4O4S2
4-[4-(2,3,4-Trifluorophenyl)sulfonylpiperazin-1-yl]thieno[2,3-d]pyrimidine chemical structure, C16H13F3N4O2S2, CAS 852131-10-3
4-[4-(2,3,4-Trifluorophenyl)sulfonylpiperazin-1-yl]thieno[2,3-d]pyrimidine
CAS 852131-10-3C16H13F3N4O2S2
4-[4-(Phenylsulfonyl)-1-piperazinyl]thieno[2,3-d]pyrimidine chemical structure, C16H16N4O2S2, CAS 678139-32-7
4-[4-(Phenylsulfonyl)-1-piperazinyl]thieno[2,3-d]pyrimidine
CAS 678139-32-7C16H16N4O2S2