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Murcko scaffold

Ring system with 4 rings and 23 atoms

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
11
With full pages
3
Scaffold SMILES

O=C1C(=Cc2ccco2)Oc2c(CN3CCCCC3)cccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C(=Cc2ccco2)Oc2c(CN3CCCCC3)cccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

(Z)-6-Hydroxy-2-((5-methylfuran-2-yl)methylene)-7-(piperidin-1-ylmethyl)benzofuran-3(2H)-one chemical structure, C20H21NO4, CAS 900273-02-1
(Z)-6-Hydroxy-2-((5-methylfuran-2-yl)methylene)-7-(piperidin-1-ylmethyl)benzofuran-3(2H)-one
CAS 900273-02-1C20H21NO4
(Z)-6-Hydroxy-2-((5-methylfuran-2-yl)methylene)-7-((4-methylpiperidin-1-yl)methyl)benzofuran-3(2H)-one chemical structure, C21H23NO4, CAS 896596-19-3
(Z)-6-Hydroxy-2-((5-methylfuran-2-yl)methylene)-7-((4-methylpiperidin-1-yl)methyl)benzofuran-3(2H)-one
CAS 896596-19-3C21H23NO4
(2Z)-2-(Furan-2-ylmethylidene)-6-hydroxy-7-(piperidin-1-ylmethyl)-1-benzofuran-3-one chemical structure, C19H19NO4, CAS 1164526-26-4
(2Z)-2-(Furan-2-ylmethylidene)-6-hydroxy-7-(piperidin-1-ylmethyl)-1-benzofuran-3-one
CAS 1164526-26-4C19H19NO4
(Z)-2-(Furan-2-ylmethylene)-6-hydroxy-7-((2-methylpiperidin-1-yl)methyl)benzofuran-3(2H)-one chemical structure, C20H21NO4, CAS 896070-05-6
(Z)-2-(Furan-2-ylmethylene)-6-hydroxy-7-((2-methylpiperidin-1-yl)methyl)benzofuran-3(2H)-one
CAS 896070-05-6C20H21NO4
(Z)-2-(Furan-2-ylmethylene)-6-hydroxy-7-((4-methylpiperidin-1-yl)methyl)benzofuran-3(2H)-one chemical structure, C20H21NO4, CAS 1164557-99-6
(Z)-2-(Furan-2-ylmethylene)-6-hydroxy-7-((4-methylpiperidin-1-yl)methyl)benzofuran-3(2H)-one
CAS 1164557-99-6C20H21NO4
(Z)-7-((3,5-Dimethylpiperidin-1-yl)methyl)-2-(furan-2-ylmethylene)-6-hydroxybenzofuran-3(2H)-one chemical structure, C21H23NO4, CAS 896820-49-8
(Z)-7-((3,5-Dimethylpiperidin-1-yl)methyl)-2-(furan-2-ylmethylene)-6-hydroxybenzofuran-3(2H)-one
CAS 896820-49-8C21H23NO4
(Z)-2-(Furan-2-ylmethylene)-6-hydroxy-7-((3-methylpiperidin-1-yl)methyl)benzofuran-3(2H)-one chemical structure, C20H21NO4, CAS 1164475-84-6
(Z)-2-(Furan-2-ylmethylene)-6-hydroxy-7-((3-methylpiperidin-1-yl)methyl)benzofuran-3(2H)-one
CAS 1164475-84-6C20H21NO4
(Z)-6-Hydroxy-2-((5-methylfuran-2-yl)methylene)-7-((3-methylpiperidin-1-yl)methyl)benzofuran-3(2H)-one chemical structure, C21H23NO4, CAS 896078-46-9
(Z)-6-Hydroxy-2-((5-methylfuran-2-yl)methylene)-7-((3-methylpiperidin-1-yl)methyl)benzofuran-3(2H)-one
CAS 896078-46-9C21H23NO4
(Z)-2-(Furan-2-ylmethylene)-6-hydroxy-4-methyl-7-(piperidin-1-ylmethyl)benzofuran-3(2H)-one chemical structure, C20H21NO4, CAS 903862-78-2
(Z)-2-(Furan-2-ylmethylene)-6-hydroxy-4-methyl-7-(piperidin-1-ylmethyl)benzofuran-3(2H)-one
CAS 903862-78-2C20H21NO4
(Z)-7-((3,5-Dimethylpiperidin-1-yl)methyl)-6-hydroxy-2-((5-methylfuran-2-yl)methylene)benzofuran-3(2H)-one chemical structure, C22H25NO4, CAS 929433-33-0
(Z)-7-((3,5-Dimethylpiperidin-1-yl)methyl)-6-hydroxy-2-((5-methylfuran-2-yl)methylene)benzofuran-3(2H)-one
CAS 929433-33-0C22H25NO4
(Z)-6-Hydroxy-2-((5-methylfuran-2-yl)methylene)-7-((2-methylpiperidin-1-yl)methyl)benzofuran-3(2H)-one chemical structure, C21H23NO4, CAS 900280-05-9
(Z)-6-Hydroxy-2-((5-methylfuran-2-yl)methylene)-7-((2-methylpiperidin-1-yl)methyl)benzofuran-3(2H)-one
CAS 900280-05-9C21H23NO4