CompoundList
Sign in
Murcko scaffold

2,5-Diphenyl-3-thiophen-2-yl-3,4-dihydropyrazole scaffold

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
9
With full pages
1
Scaffold SMILES

c1ccc(C2=NN(c3ccccc3)C(c3cccs3)C2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,5-Diphenyl-3-thiophen-2-yl-3,4-dihydropyrazole page
Murcko scaffold c1ccc(C2=NN(c3ccccc3)C(c3cccs3)C2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

1H-Pyrazole, 3-(4-chlorophenyl)-4,5-dihydro-1-phenyl-5-(thienyl)- chemical structure, C19H15ClN2S, CAS 89144-82-1
1H-Pyrazole, 3-(4-chlorophenyl)-4,5-dihydro-1-phenyl-5-(thienyl)-
CAS 89144-82-1C19H15ClN2S
1H-Pyrazole, 4,5-dihydro-3-(4-methoxyphenyl)-1-phenyl-5-(2-thienyl)- chemical structure, C20H18N2OS, CAS 20264-73-7
1H-Pyrazole, 4,5-dihydro-3-(4-methoxyphenyl)-1-phenyl-5-(2-thienyl)-
CAS 20264-73-7C20H18N2OS
5-(4-Bromophenyl)-2-(2,4-difluorophenyl)-3-thiophen-2-yl-3,4-dihydropyrazole chemical structure, C19H13BrF2N2S, CAS 331446-04-9
5-(4-Bromophenyl)-2-(2,4-difluorophenyl)-3-thiophen-2-yl-3,4-dihydropyrazole
CAS 331446-04-9C19H13BrF2N2S
2-(4-Bromophenyl)-5-(4-methoxyphenyl)-3-thiophen-2-yl-3,4-dihydropyrazole chemical structure, C20H17BrN2OS, CAS 331446-06-1
2-(4-Bromophenyl)-5-(4-methoxyphenyl)-3-thiophen-2-yl-3,4-dihydropyrazole
CAS 331446-06-1C20H17BrN2OS
3-(4-Methylphenyl)-1-phenyl-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole chemical structure, C20H18N2S, CAS 5906-18-3
3-(4-Methylphenyl)-1-phenyl-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole
CAS 5906-18-3C20H18N2S
1-(2,4-Difluorophenyl)-4,5-dihydro-3-(4-methylphenyl)-5-(2-thienyl)-1H-pyrazole chemical structure, C20H16F2N2S, CAS 353773-24-7
1-(2,4-Difluorophenyl)-4,5-dihydro-3-(4-methylphenyl)-5-(2-thienyl)-1H-pyrazole
CAS 353773-24-7C20H16F2N2S
1-(4-Fluorophenyl)-3-(4-methylphenyl)-5-(2-thienyl)-4,5-dihydro-1H-pyrazole chemical structure, C20H17FN2S, CAS 353770-89-5
1-(4-Fluorophenyl)-3-(4-methylphenyl)-5-(2-thienyl)-4,5-dihydro-1H-pyrazole
CAS 353770-89-5C20H17FN2S
2-(4-Chlorophenyl)-5-(4-fluorophenyl)-3-thiophen-2-yl-3,4-dihydropyrazole chemical structure, C19H14ClFN2S, CAS 354558-83-1
2-(4-Chlorophenyl)-5-(4-fluorophenyl)-3-thiophen-2-yl-3,4-dihydropyrazole
CAS 354558-83-1C19H14ClFN2S
2,5-Diphenyl-3-thiophen-2-yl-3,4-dihydropyrazole chemical structure, C19H16N2S, CAS 2755-72-8
2,5-Diphenyl-3-thiophen-2-yl-3,4-dihydropyrazole
CAS 2755-72-8C19H16N2S