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Murcko scaffold

Ring system with 3 rings and 20 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
16
With full pages
1
Scaffold SMILES

O=C(Nc1cccc(-c2cccs2)c1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cccc(-c2cccs2)c1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

4-Acetamido-N-(2-amino-5-(thiophen-2-yl)phenyl)benzamide chemical structure, C19H17N3O2S, CAS 849234-64-6
4-Acetamido-N-(2-amino-5-(thiophen-2-yl)phenyl)benzamide
CAS 849234-64-6C19H17N3O2S
N-[2-Amino-5-(thiophen-2-yl)phenyl]-4-methoxybenzamide chemical structure, C18H16N2O2S, CAS 849234-80-6
N-[2-Amino-5-(thiophen-2-yl)phenyl]-4-methoxybenzamide
CAS 849234-80-6C18H16N2O2S
Benzeneacetamide,4-[[[2-amino-5-(2-thienyl)phenyl]amino]carbonyl]-a-hydroxy- chemical structure, C19H17N3O3S, CAS 945401-19-4
Benzeneacetamide,4-[[[2-amino-5-(2-thienyl)phenyl]amino]carbonyl]-a-hydroxy-
CAS 945401-19-4C19H17N3O3S
Methyl 4-((2-amino-5-(thiophen-2-yl)phenyl)carbamoyl)benzylcarbamate chemical structure, C20H19N3O3S, CAS 1013330-84-1
Methyl 4-((2-amino-5-(thiophen-2-yl)phenyl)carbamoyl)benzylcarbamate
CAS 1013330-84-1C20H19N3O3S
N-[2-Amino-5-(2-thienyl)phenyl]benzamide chemical structure, C17H14N2OS, CAS 849234-83-9
N-[2-Amino-5-(2-thienyl)phenyl]benzamide
CAS 849234-83-9C17H14N2OS
Methyl 4-[({2-[(tert-butoxycarbonyl)amino]-5-thien-2-ylphenyl}amino)carbonyl]benzoate chemical structure, C24H24N2O5S, CAS 945401-61-6
Methyl 4-[({2-[(tert-butoxycarbonyl)amino]-5-thien-2-ylphenyl}amino)carbonyl]benzoate
CAS 945401-61-6C24H24N2O5S
tert-Butyl [2-{[4-(aminomethyl)benzoyl]amino}-4-(2-thienyl)phenyl]carbamate chemical structure, C23H25N3O3S, CAS 1003315-95-4
tert-Butyl [2-{[4-(aminomethyl)benzoyl]amino}-4-(2-thienyl)phenyl]carbamate
CAS 1003315-95-4C23H25N3O3S
tert-Butyl [2-{[4-(bromomethyl)benzoyl]amino}-4-(2-thienyl)phenyl]carbamate chemical structure, C23H23BrN2O3S, CAS 1003313-84-5
tert-Butyl [2-{[4-(bromomethyl)benzoyl]amino}-4-(2-thienyl)phenyl]carbamate
CAS 1003313-84-5C23H23BrN2O3S
N-(2-Amino-5-(5-methylthiophen-2-yl)phenyl)-4-methoxybenzamide chemical structure, C19H18N2O2S, CAS 849234-99-7
N-(2-Amino-5-(5-methylthiophen-2-yl)phenyl)-4-methoxybenzamide
CAS 849234-99-7C19H18N2O2S
tert-Butyl 2-(3-methoxybenzamido)-4-(thiophen-2-yl)phenylcarbamate chemical structure, C23H24N2O4S, CAS 849236-41-5
tert-Butyl 2-(3-methoxybenzamido)-4-(thiophen-2-yl)phenylcarbamate
CAS 849236-41-5C23H24N2O4S
tert-Butyl 2-(4-bromobenzamido)-4-(thiophen-2-yl)phenylcarbamate chemical structure, C22H21BrN2O3S, CAS 849237-10-1
tert-Butyl 2-(4-bromobenzamido)-4-(thiophen-2-yl)phenylcarbamate
CAS 849237-10-1C22H21BrN2O3S
[2-[[4-(Acetyloxy)benzoyl]amino]-4-(2-thienyl)phenyl]carbamic acid 1,1-dimethylethyl ester chemical structure, C24H24N2O5S, CAS 849236-42-6
[2-[[4-(Acetyloxy)benzoyl]amino]-4-(2-thienyl)phenyl]carbamic acid 1,1-dimethylethyl ester
CAS 849236-42-6C24H24N2O5S
N-[2-Amino-5-(2-thienyl)phenyl]-4-bromobenzamide chemical structure, C17H13BrN2OS, CAS 849234-81-7
N-[2-Amino-5-(2-thienyl)phenyl]-4-bromobenzamide
CAS 849234-81-7C17H13BrN2OS
tert-Butyl 2-(4-(chloromethyl)benzamido)-4-(thiophen-2-yl)phenylcarbamate chemical structure, C23H23ClN2O3S, CAS 953434-83-8
tert-Butyl 2-(4-(chloromethyl)benzamido)-4-(thiophen-2-yl)phenylcarbamate
CAS 953434-83-8C23H23ClN2O3S
N-[[4-[[[2-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-(2-thienyl)phenyl]amino]carbonyl]phenyl]methyl]carbamic acid methyl ester chemical structure, C25H27N3O5S, CAS 1013330-90-9
N-[[4-[[[2-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-(2-thienyl)phenyl]amino]carbonyl]phenyl]methyl]carbamic acid methyl ester
CAS 1013330-90-9C25H27N3O5S
4-Acetamido-N-(2-nitro-5-(thiophen-2-yl)phenyl)benzamide chemical structure, C19H15N3O4S, CAS 2749585-92-8
4-Acetamido-N-(2-nitro-5-(thiophen-2-yl)phenyl)benzamide
CAS 2749585-92-8C19H15N3O4S