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Murcko scaffold

Ring system with 3 rings and 14 atoms

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
6
With full pages
1
Scaffold SMILES

O=C1C=C2c3ccccc3CC2CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=C2c3ccccc3CC2CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

DPOFA chemical structure, C18H18Cl2O4, CAS 81997-33-3
DPOFA
CAS 81997-33-3C18H18Cl2O4
3H-Fluoren-3-one, 7-amino-4-bromo-9a-butyl-1,2,9,9a-tetrahydro- chemical structure, C17H20BrNO, CAS 371758-62-2
3H-Fluoren-3-one, 7-amino-4-bromo-9a-butyl-1,2,9,9a-tetrahydro-
CAS 371758-62-2C17H20BrNO
[[(9aS)-5,6-Dichloro-2,3,9,9a-tetrahydro-3-oxo-9a-propyl-1H-fluoren-7-yl]oxy]acetic acid chemical structure, C18H18Cl2O4, CAS 101469-39-0
[[(9aS)-5,6-Dichloro-2,3,9,9a-tetrahydro-3-oxo-9a-propyl-1H-fluoren-7-yl]oxy]acetic acid
CAS 101469-39-0C18H18Cl2O4
6-Chloro-9a-(2-fluoroethyl)-7-methoxy-9,9a-dihydro-1H-fluoren-3(2H)-one chemical structure, C16H16ClFO2, CAS 1039456-85-3
6-Chloro-9a-(2-fluoroethyl)-7-methoxy-9,9a-dihydro-1H-fluoren-3(2H)-one
CAS 1039456-85-3C16H16ClFO2
8-Chloro-9a-(2-fluoroethyl)-7-methoxy-1,2,9,9a-tetrahydrofluoren-3-one chemical structure, C16H16ClFO2, CAS 886036-95-9
8-Chloro-9a-(2-fluoroethyl)-7-methoxy-1,2,9,9a-tetrahydrofluoren-3-one
CAS 886036-95-9C16H16ClFO2
(9aS)-9a-Methyl-1,2,9,9a-tetrahydro-3H-fluoren-3-one chemical structure, C14H14O, CAS 62241-75-2
(9aS)-9a-Methyl-1,2,9,9a-tetrahydro-3H-fluoren-3-one
CAS 62241-75-2C14H14O