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Murcko scaffold

Ring system with 3 rings and 24 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
10
With full pages
3
Scaffold SMILES

O=C(C=Cc1cccc(Oc2ccccc2)c1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1cccc(Oc2ccccc2)c1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

2-Cyano-N-(3,4-dimethoxyphenyl)-3-(3-phenoxyphenyl)prop-2-enamide chemical structure, C24H20N2O4, CAS 744223-05-0
2-Cyano-N-(3,4-dimethoxyphenyl)-3-(3-phenoxyphenyl)prop-2-enamide
CAS 744223-05-0C24H20N2O4
(E)-2-Cyano-N-(3-methoxyphenyl)-3-(3-phenoxyphenyl)prop-2-enamide chemical structure, C23H18N2O3, CAS 358990-09-7
(E)-2-Cyano-N-(3-methoxyphenyl)-3-(3-phenoxyphenyl)prop-2-enamide
CAS 358990-09-7C23H18N2O3
(E)-2-Cyano-N-(2,6-dimethylphenyl)-3-(3-phenoxyphenyl)prop-2-enamide chemical structure, C24H20N2O2, CAS 444592-53-4
(E)-2-Cyano-N-(2,6-dimethylphenyl)-3-(3-phenoxyphenyl)prop-2-enamide
CAS 444592-53-4C24H20N2O2
(E)-N-(4-Chloro-2-nitrophenyl)-2-cyano-3-[3-(2,4-dinitrophenoxy)-4-methoxyphenyl]prop-2-enamide chemical structure, C23H14ClN5O9, CAS 522657-59-6
(E)-N-(4-Chloro-2-nitrophenyl)-2-cyano-3-[3-(2,4-dinitrophenoxy)-4-methoxyphenyl]prop-2-enamide
CAS 522657-59-6C23H14ClN5O9
N-(2,4-Dimethoxyphenyl)-3-(3-phenoxyphenyl)acrylamide chemical structure, C23H21NO4, CAS 478258-23-0
N-(2,4-Dimethoxyphenyl)-3-(3-phenoxyphenyl)acrylamide
CAS 478258-23-0C23H21NO4
N-(4-Bromo-3-methylphenyl)-3-(3-phenoxyphenyl)acrylamide chemical structure, C22H18BrNO2, CAS 478258-27-4
N-(4-Bromo-3-methylphenyl)-3-(3-phenoxyphenyl)acrylamide
CAS 478258-27-4C22H18BrNO2
2-[[(E)-2-Cyano-3-(3-phenoxyphenyl)prop-2-enoyl]amino]benzoic acid chemical structure, C23H16N2O4, CAS 330830-05-2
2-[[(E)-2-Cyano-3-(3-phenoxyphenyl)prop-2-enoyl]amino]benzoic acid
CAS 330830-05-2C23H16N2O4
N-(3,4-Dimethylphenyl)-3-(3-phenoxyphenyl)acrylamide chemical structure, C23H21NO2, CAS 478258-20-7
N-(3,4-Dimethylphenyl)-3-(3-phenoxyphenyl)acrylamide
CAS 478258-20-7C23H21NO2
(E)-2-Cyano-N-(2-methoxyphenyl)-3-(3-phenoxyphenyl)prop-2-enamide chemical structure, C23H18N2O3, CAS 359779-37-6
(E)-2-Cyano-N-(2-methoxyphenyl)-3-(3-phenoxyphenyl)prop-2-enamide
CAS 359779-37-6C23H18N2O3
2-({2-Cyano-3-[3-(2-cyano-4-nitrophenoxy)phenyl]prop-2-enoyl}amino)benzoic acid chemical structure, C24H14N4O6, CAS 402602-00-0
2-({2-Cyano-3-[3-(2-cyano-4-nitrophenoxy)phenyl]prop-2-enoyl}amino)benzoic acid
CAS 402602-00-0C24H14N4O6