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Murcko scaffold

Ring system with 3 rings and 24 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
8
With full pages
2
Scaffold SMILES

O=C(CCS(=O)(=O)c1ccccc1)Nc1nnc(-c2cccs2)o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCS(=O)(=O)c1ccccc1)Nc1nnc(-c2cccs2)o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

N-(5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl)-3-tosylpropanamide chemical structure, C16H15N3O4S2, CAS 898414-55-6
N-(5-(Thiophen-2-yl)-1,3,4-oxadiazol-2-yl)-3-tosylpropanamide
CAS 898414-55-6C16H15N3O4S2
3-(4-Chlorophenyl)sulfonyl-N-(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)propanamide chemical structure, C15H12ClN3O4S2, CAS 898437-26-8
3-(4-Chlorophenyl)sulfonyl-N-(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)propanamide
CAS 898437-26-8C15H12ClN3O4S2
3-((4-Fluorophenyl)sulfonyl)-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)propanamide chemical structure, C15H12FN3O4S2, CAS 895451-54-4
3-((4-Fluorophenyl)sulfonyl)-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)propanamide
CAS 895451-54-4C15H12FN3O4S2
3-((4-Methoxyphenyl)sulfonyl)-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)propanamide chemical structure, C16H15N3O5S2, CAS 922985-38-4
3-((4-Methoxyphenyl)sulfonyl)-N-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)propanamide
CAS 922985-38-4C16H15N3O5S2
N-(5-(5-Bromothiophen-2-yl)-1,3,4-oxadiazol-2-yl)-3-((4-chlorophenyl)sulfonyl)propanamide chemical structure, C15H11BrClN3O4S2, CAS 1040642-78-1
N-(5-(5-Bromothiophen-2-yl)-1,3,4-oxadiazol-2-yl)-3-((4-chlorophenyl)sulfonyl)propanamide
CAS 1040642-78-1C15H11BrClN3O4S2
N-(5-(5-Bromothiophen-2-yl)-1,3,4-oxadiazol-2-yl)-3-((4-fluorophenyl)sulfonyl)propanamide chemical structure, C15H11BrFN3O4S2, CAS 1021105-16-7
N-(5-(5-Bromothiophen-2-yl)-1,3,4-oxadiazol-2-yl)-3-((4-fluorophenyl)sulfonyl)propanamide
CAS 1021105-16-7C15H11BrFN3O4S2
N-(5-(5-Bromothiophen-2-yl)-1,3,4-oxadiazol-2-yl)-3-(phenylsulfonyl)propanamide chemical structure, C15H12BrN3O4S2, CAS 1021071-02-2
N-(5-(5-Bromothiophen-2-yl)-1,3,4-oxadiazol-2-yl)-3-(phenylsulfonyl)propanamide
CAS 1021071-02-2C15H12BrN3O4S2
N-(5-(5-Bromothiophen-2-yl)-1,3,4-oxadiazol-2-yl)-3-((4-methoxyphenyl)sulfonyl)propanamide chemical structure, C16H14BrN3O5S2, CAS 1021105-24-7
N-(5-(5-Bromothiophen-2-yl)-1,3,4-oxadiazol-2-yl)-3-((4-methoxyphenyl)sulfonyl)propanamide
CAS 1021105-24-7C16H14BrN3O5S2