Murcko scaffold
Ring system with 2 rings and 13 atoms
196 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 13
- Chemicals
- 196
- With full pages
- 8
Scaffold SMILES
O=S(=O)(c1ccccc1)N1CCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 196 chemicals
1-(p-Toluenesulfonyl)azetidine
CAS 7730-45-2C10H13NO2S
Azetidine, 2-methyl-1-(p-tolylsulfonyl)-
CAS 13595-47-6C11H15NO2S
(S)-1-Tosylazetidine-2-carboxylic acid
CAS 39897-13-7C11H13NO4S
Ethyl 1-(benzenesulfonyl)azetidine-3-carboxylate
CAS 866152-75-2C12H15NO4S
![Ethyl 1-[(4-fluorophenyl)sulfonyl]-3-azetanecarboxylate chemical structure, C12H14FNO4S, CAS 866152-77-4](/s/SZPXHIDJDTWEJH-UHFFFAOYSA-N.svg)
Ethyl 1-[(4-fluorophenyl)sulfonyl]-3-azetanecarboxylate
CAS 866152-77-4C12H14FNO4S
![Ethyl 1-[(4-methylphenyl)sulfonyl]-3-azetanecarboxylate chemical structure, C13H17NO4S, CAS 866152-78-5](/s/GIGLAPQDMSNSIJ-UHFFFAOYSA-N.svg)
Ethyl 1-[(4-methylphenyl)sulfonyl]-3-azetanecarboxylate
CAS 866152-78-5C13H17NO4S
![Ethyl 1-[(2,5-dimethoxyphenyl)sulfonyl]-3-azetanecarboxylate chemical structure, C14H19NO6S, CAS 866152-79-6](/s/ADIQIJRZGRHAMK-UHFFFAOYSA-N.svg)
Ethyl 1-[(2,5-dimethoxyphenyl)sulfonyl]-3-azetanecarboxylate
CAS 866152-79-6C14H19NO6S
![Ethyl 1-[(5-chloro-2-nitrophenyl)sulfonyl]-3-azetanecarboxylate chemical structure, C12H13ClN2O6S, CAS 866152-80-9](/s/VKZMABMKFNQKOS-UHFFFAOYSA-N.svg)
Ethyl 1-[(5-chloro-2-nitrophenyl)sulfonyl]-3-azetanecarboxylate
CAS 866152-80-9C12H13ClN2O6S
1-(4-Fluorobenzenesulfonyl)azetidine-3-carboxylic acid
CAS 866043-35-8C10H10FNO4S
1-Tosylazetidin-3-ol
CAS 154010-96-5C10H13NO3S
![2-Azetidinecarboxylic acid, 1-[(4-methylphenyl)sulfonyl]- chemical structure, C11H13NO4S, CAS 17481-44-6](/s/PCZMDMOEFYSSGY-UHFFFAOYSA-N.svg)
2-Azetidinecarboxylic acid, 1-[(4-methylphenyl)sulfonyl]-
CAS 17481-44-6C11H13NO4S
1-((4-Bromophenyl)sulfonyl)azetidine
CAS 530081-57-3C9H10BrNO2S
(S)-N-(2-Nitrobenzenesulfonyl)azetidine-2-carboxylic acid
CAS 207791-17-1C10H10N2O6S
![Azetidine, 2-butyl-3-ethyl-1-[(4-methylphenyl)sulfonyl]-, (2R,3S)- chemical structure, C16H25NO2S, CAS 825601-53-4](/s/JAEDHYJDXPIIKQ-GOEBONIOSA-N.svg)
Azetidine, 2-butyl-3-ethyl-1-[(4-methylphenyl)sulfonyl]-, (2R,3S)-
CAS 825601-53-4C16H25NO2S
![Azetidine, 3-butyl-2-hexyl-1-[(4-methylphenyl)sulfonyl]-, (2R,3S)- chemical structure, C20H33NO2S, CAS 825601-55-6](/s/HJUAMBXGOKZEJY-AZUAARDMSA-N.svg)
Azetidine, 3-butyl-2-hexyl-1-[(4-methylphenyl)sulfonyl]-, (2R,3S)-
CAS 825601-55-6C20H33NO2S
![Azetidine, 2-butyl-3-methyl-1-[(4-methylphenyl)sulfonyl]-, (2R,3S)- chemical structure, C15H23NO2S, CAS 825601-51-2](/s/PIEDJCIBGHVRFC-DZGCQCFKSA-N.svg)
Azetidine, 2-butyl-3-methyl-1-[(4-methylphenyl)sulfonyl]-, (2R,3S)-
CAS 825601-51-2C15H23NO2S
![Azetidine, 2-hexyl-1-[(4-methylphenyl)sulfonyl]-, (2R)- chemical structure, C16H25NO2S, CAS 825601-61-4](/s/BTZWYGDKRAALMZ-OAHLLOKOSA-N.svg)
Azetidine, 2-hexyl-1-[(4-methylphenyl)sulfonyl]-, (2R)-
CAS 825601-61-4C16H25NO2S
![1-[(4-Methylphenyl)sulfonyl]-2-azetidinecarboxylic acid chemical structure, C11H13NO4S, CAS 174740-80-8](/s/PCZMDMOEFYSSGY-SNVBAGLBSA-N.svg)
1-[(4-Methylphenyl)sulfonyl]-2-azetidinecarboxylic acid
CAS 174740-80-8C11H13NO4S
3,3-Dimethyl-1-tosylazetidine
CAS 79201-18-6C12H17NO2S
3-Chloro-1-(4-methylbenzene-1-sulfonyl)azetidine
CAS 24083-59-8C10H12ClNO2S
3-(Azetidine-1-sulfonyl)-4-fluorobenzoic acid
CAS 926259-66-7C10H10FNO4S
3-(Azetidine-1-sulfonyl)benzoic acid
CAS 872092-00-7C10H11NO4S
5-(Azetidine-1-sulfonyl)-2-chlorobenzoic acid
CAS 926227-65-8C10H10ClNO4S
1-(3,5-Dichlorophenyl)sulfonyl-2-methylazetidine-2-carboxylic acid
CAS 309977-82-0C11H11Cl2NO4S
- 1-Tosylazetidine-3-carboxylic acid92993-58-3C11H13NO4S
- N-Tosyl-3-hydroxymethyl azetidine-3-carboxylic acid92993-56-1C12H15NO5S
- [3-(Hydroxymethyl)-1-(4-methylbenzenesulfonyl)azetidin-3-yl]methanol92993-54-9C12H17NO4S
- 1,1-Dimethylethyl 3-chloro-1-[(4-methylphenyl)sulfonyl]-3-azetidinecarboxylate53871-11-7C15H20ClNO4S
- 1-(Phenylsulfonyl)-2-azetidinecarboxylic acid69539-49-7C10H11NO4S
- 4-(Azetidin-1-ylsulfonyl)aniline482308-17-8C9H12N2O2S
- 5-(Azetidine-1-sulfonyl)-2-methoxybenzoic acid89704-59-6C11H13NO5S
- 1-((4-Chlorophenyl)sulfonyl)azetidine870530-41-9C9H10ClNO2S
- 3-(Azetidin-1-ylsulfonyl)-4-methylbenzoic acid1046271-18-4C11H13NO4S
- B-(4-(1-Azetidinylsulfonyl)phenyl)boronic acid871329-68-9C9H12BNO4S
- 1-(3-Bromophenylsulfonyl)azetidine1133116-29-6C9H10BrNO2S
- 1-(Benzenesulfonyl)azetidine-3-carboxylic acid1219828-14-4C10H11NO4S
- 1-(2-Ethoxybenzene-1-sulfonyl)-3-fluoroazetidine1202781-51-8C11H14FNO3S
- Methyl 1-(benzenesulfonyl)azetidine-3-carboxylate1334499-99-8C11H13NO4S
- 3,3-Bis(bromomethyl)-1-(4-methylbenzenesulfonyl)azetidine1041026-61-2C12H15Br2NO2S
- [3-(Bromomethyl)-1-tosylazetidin-3-yl]methanol1041026-55-4C12H16BrNO3S
- 1-(Phenylsulfonyl)azetidin-3-amine HCl1211541-61-5C9H12N2O2S
- Azetidine, 1-[(4-fluorophenyl)sulfonyl]-871657-66-8C9H10FNO2S
- 1-[(4-Bromo-3-methylphenyl)sulfonyl]-3-azetidinol1340189-70-9C10H12BrNO3S
- 1-(4-Chloro-2-methylbenzene-1-sulfonyl)azetidin-3-ol1339163-02-8C10H12ClNO3S
- 1-(4-Bromophenylsulfonyl)azetidin-3-ol1340536-74-4C9H10BrNO3S
- 1-(4-Methoxybenzenesulfonyl)azetidin-3-amine1340491-78-2C10H14N2O3S
- 1-(2-Methyl-5-nitrobenzenesulfonyl)azetidin-3-amine1495622-24-6C10H13N3O4S
- 1-[4-(Trifluoromethyl)benzenesulfonyl]azetidin-3-amine1484160-50-0C10H11F3N2O2S
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(CC2CCC2)cc148 chemicals
c1ccc(CC2CNC2)cc141 chemicals
c1ccc(OC2CNC2)cc131 chemicals
c1ccc(CN2CCC2)cc115 chemicals
c1ccc(NC2COC2)cc114 chemicals
c1ccc(NC2CCC2)cc112 chemicals
c1ccc(OC2CCC2)cc112 chemicals
c1ccc(OC2COC2)cc110 chemicals
c1ccc(CC2COC2)cc18 chemicals
c1ccc(OC2CCC2)nc18 chemicals
C(=C1CNC1)c1ccccc16 chemicals
c1ccc(NC2CNC2)cc15 chemicals