Murcko scaffold
N-Phenylazetidin-3-amine scaffold
75 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 11
- Chemicals
- 75
- With full pages
- 5
Scaffold SMILES
c1ccc(NC2CNC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 75 chemicals
2-(3-Azetidinylamino)benzenemethanol
CAS 162045-62-7C10H14N2O
N-Phenylazetidin-3-amine
CAS 744984-91-6C9H12N2
N-(Azetidin-3-yl)-N-phenylacetamide
CAS 791528-70-6C11H14N2O
tert-Butyl 3-(2-bromoanilino)azetidine-1-carboxylate
CAS 887579-47-7C14H19BrN2O2
tert-Butyl 3-(2-fluoroanilino)azetidine-1-carboxylate
CAS 887579-99-9C14H19FN2O2
tert-Butyl 3-(3-bromoanilino)azetidine-1-carboxylate
CAS 887579-41-1C14H19BrN2O2
tert-Butyl 3-(3-fluoroanilino)azetidine-1-carboxylate
CAS 887580-05-4C14H19FN2O2
tert-Butyl 3-(4-bromoanilino)azetidine-1-carboxylate
CAS 887579-54-6C14H19BrN2O2
![tert-Butyl 3-[(4-fluorophenyl)amino]azetidine-1-carboxylate chemical structure, C14H19FN2O2, CAS 887580-12-3](/s/IZSRXFFAYHXHRV-UHFFFAOYSA-N.svg)
tert-Butyl 3-[(4-fluorophenyl)amino]azetidine-1-carboxylate
CAS 887580-12-3C14H19FN2O2
1-Boc-3-(4-trifluoromethyl-phenylamino)-azetidine
CAS 887580-36-1C15H19F3N2O2
![tert-Butyl 3-[3-(trifluoromethyl)anilino]azetidine-1-carboxylate chemical structure, C15H19F3N2O2, CAS 887580-44-1](/s/UDDYWGGZNODNAJ-UHFFFAOYSA-N.svg)
tert-Butyl 3-[3-(trifluoromethyl)anilino]azetidine-1-carboxylate
CAS 887580-44-1C15H19F3N2O2
N-(4-Fluorophenyl)azetidin-3-amine
CAS 920511-30-4C9H11FN2
N-(2-tert-Butylphenyl)azetidin-3-amine
CAS 1146956-93-5C13H20N2
tert-Butyl 3-(2-nitroanilino)azetidine-1-carboxylate
CAS 1477963-33-9C14H19N3O4
tert-Butyl 3-((4-(methylthio)phenyl)amino)azetidine-1-carboxylate
CAS 1495567-73-1C15H22N2O2S
![1,1-Dimethylethyl 3-[[2-(1-methylethyl)phenyl]amino]-1-azetidinecarboxylate chemical structure, C17H26N2O2, CAS 1405003-02-2](/s/NEYFAUYIUHOHHP-UHFFFAOYSA-N.svg)
1,1-Dimethylethyl 3-[[2-(1-methylethyl)phenyl]amino]-1-azetidinecarboxylate
CAS 1405003-02-2C17H26N2O2
tert-Butyl 3-((2-cyanophenyl)amino)azetidine-1-carboxylate
CAS 1411200-89-9C15H19N3O2
tert-Butyl 3-(phenylamino)azetidine-1-carboxylate
CAS 1285278-84-3C14H20N2O2
![1,1-Dimethylethyl 3-[(4-cyanophenyl)amino]-1-azetidinecarboxylate chemical structure, C15H19N3O2, CAS 1406055-87-5](/s/ZODHUKDUYKQOPK-UHFFFAOYSA-N.svg)
1,1-Dimethylethyl 3-[(4-cyanophenyl)amino]-1-azetidinecarboxylate
CAS 1406055-87-5C15H19N3O2
tert-Butyl 3-((2-bromo-4-fluorophenyl)amino)azetidine-1-carboxylate
CAS 1494331-74-6C14H18BrFN2O2
tert-Butyl 3-((4-fluoro-2-methylphenyl)amino)azetidine-1-carboxylate
CAS 1380752-59-9C15H21FN2O2
![N-[3-Bromo-5-(trifluoromethyl)phenyl]azetidin-3-amine chemical structure, C10H10BrF3N2, CAS 1498828-69-5](/s/IVOMSXVDTNDHFD-UHFFFAOYSA-N.svg)
N-[3-Bromo-5-(trifluoromethyl)phenyl]azetidin-3-amine
CAS 1498828-69-5C10H10BrF3N2
![3-[(Azetidin-3-yl)amino]benzonitrile chemical structure, C10H11N3, CAS 1478599-43-7](/s/FZWHLDQYIGVBKI-UHFFFAOYSA-N.svg)
3-[(Azetidin-3-yl)amino]benzonitrile
CAS 1478599-43-7C10H11N3
N-(4-Bromophenyl)azetidin-3-amine
CAS 1488139-60-1C9H11BrN2
- 4-(Azetidin-3-ylamino)benzoic acid1429410-60-5C10H12N2O2
- N-(3-Bromophenyl)azetidin-3-amine1493264-54-2C9H11BrN2
- Methyl 3-[(azetidin-3-yl)amino]benzoate1496234-34-4C11H14N2O2
- 4-(3-Azetidinylamino)benzonitrile1468837-32-2C10H11N3
- N-[2-(1-Methylethyl)phenyl]-3-azetidinamine1479660-45-1C12H18N2
- N-(4-Fluoro-2-methylphenyl)azetidin-3-amine1380753-04-7C10H13FN2
- N-(3-Fluoro-4-methoxyphenyl)azetidin-3-amine1495869-76-5C10H13FN2O
- N-(4-Chloro-2-nitrophenyl)azetidin-3-amine1479865-33-2C9H10ClN3O2
- N-(3-Methoxy-4-nitrophenyl)azetidin-3-amine1375465-21-6C10H13N3O3
- 4-(Azetidin-3-ylamino)-3-nitrobenzenesulfonamide1257048-79-5C9H12N4O4S
- tert-Butyl 3-(2-nitro-4-sulfamoylanilino)azetidine-1-carboxylate1257048-78-4C14H20N4O6S
- N-(4-Fluoro-2-methylphenyl)-N-methylazetidin-3-amine1380753-05-8C11H15FN2
- tert-Butyl 3-(4-amino-3-methoxyanilino)azetidine-1-carboxylate1375465-25-0C15H23N3O3
- 1-(3-((4-Amino-3-methoxyphenyl)amino)azetidin-1-yl)ethanone1375465-31-8C12H17N3O2
- tert-Butyl 3-(3-methoxy-4-nitrophenylamino)azetidine-1-carboxylate1375465-19-2C15H21N3O5
- N-(4-Fluorophenyl)azetidin-3-amine dihydrochloride1803590-37-5C9H13Cl2FN2
- N-Methyl-N-phenylazetidin-3-amine1494470-33-5C10H14N2
- tert-Butyl 3-cyano-3-((4-fluorophenyl)amino)azetidine-1-carboxylate1537699-08-3C15H18FN3O2
- tert-Butyl 3-((2-bromo-5-chlorophenyl)amino)azetidine-1-carboxylate1537494-71-5C14H18BrClN2O2
- tert-Butyl 3-((2-bromo-5-methylphenyl)amino)azetidine-1-carboxylate1552039-20-9C15H21BrN2O2
- N-(3-Bromo-5-methoxyphenyl)azetidin-3-amine1556103-39-9C10H13BrN2O
- N1-(1-(2-fluoroethyl)azetidin-3-yl)-3-methoxybenzene-1,4-diamine1375465-27-2C12H18FN3O
- 1-(2-Fluoroethyl)-N-(3-methoxy-4-nitrophenyl)azetidin-3-amine1375465-23-8C12H16FN3O3
- tert-Butyl 3-(5-bromo-2-nitro-anilino)azetidine-1-carboxylate1471262-47-1C14H18BrN3O4
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(CC2CCC2)cc148 chemicals
c1ccc(CC2CNC2)cc141 chemicals
c1ccc(OC2CNC2)cc131 chemicals
c1ccc(CN2CCC2)cc115 chemicals
c1ccc(NC2COC2)cc114 chemicals
c1ccc(NC2CCC2)cc112 chemicals
c1ccc(OC2CCC2)cc112 chemicals
c1ccc(OC2COC2)cc110 chemicals
c1ccc(CC2COC2)cc18 chemicals
O=S(=O)(c1ccccc1)N1CCC18 chemicals
c1ccc(OC2CCC2)nc18 chemicals
C(=C1CNC1)c1ccccc16 chemicals