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Murcko scaffold

Ring system with 2 rings and 19 atoms

18 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
18
With full pages
6
Scaffold SMILES

O=C(Nc1ccccc1)C(=S)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)C(=S)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

1-(Benzylcarbamothioyl)-N-(4-ethoxyphenyl)formamide chemical structure, C17H18N2O2S, CAS 329078-52-6
1-(Benzylcarbamothioyl)-N-(4-ethoxyphenyl)formamide
CAS 329078-52-6C17H18N2O2S
2-(Benzylamino)-N-(3-chloro-4-fluorophenyl)-2-sulfanylideneacetamide chemical structure, C15H12ClFN2OS, CAS 329078-64-0
2-(Benzylamino)-N-(3-chloro-4-fluorophenyl)-2-sulfanylideneacetamide
CAS 329078-64-0C15H12ClFN2OS
2-(Benzylamino)-N-(2,3-dimethylphenyl)-2-thioxoacetamide chemical structure, C17H18N2OS, CAS 329078-70-8
2-(Benzylamino)-N-(2,3-dimethylphenyl)-2-thioxoacetamide
CAS 329078-70-8C17H18N2OS
2-(Benzylamino)-2-thioxo-N-(3-(trifluoromethyl)phenyl)acetamide chemical structure, C16H13F3N2OS, CAS 271798-63-1
2-(Benzylamino)-2-thioxo-N-(3-(trifluoromethyl)phenyl)acetamide
CAS 271798-63-1C16H13F3N2OS
2-(Benzylamino)-N-(2-methoxy-5-methylphenyl)-2-thioxoacetamide chemical structure, C17H18N2O2S, CAS 329078-92-4
2-(Benzylamino)-N-(2-methoxy-5-methylphenyl)-2-thioxoacetamide
CAS 329078-92-4C17H18N2O2S
2-(Benzylamino)-N-(3-chlorophenyl)-2-sulfanylideneacetamide chemical structure, C15H13ClN2OS, CAS 329079-21-2
2-(Benzylamino)-N-(3-chlorophenyl)-2-sulfanylideneacetamide
CAS 329079-21-2C15H13ClN2OS
2-(Benzylamino)-N-(3,5-dimethylphenyl)-2-thioxoacetamide chemical structure, C17H18N2OS, CAS 329079-46-1
2-(Benzylamino)-N-(3,5-dimethylphenyl)-2-thioxoacetamide
CAS 329079-46-1C17H18N2OS
2-(Benzylamino)-N-(4-methoxyphenyl)-2-thioxoacetamide chemical structure, C16H16N2O2S, CAS 298217-89-7
2-(Benzylamino)-N-(4-methoxyphenyl)-2-thioxoacetamide
CAS 298217-89-7C16H16N2O2S
2-(Benzylamino)-N-(4-methylphenyl)-2-thioxoacetamide chemical structure, C16H16N2OS, CAS 380626-05-1
2-(Benzylamino)-N-(4-methylphenyl)-2-thioxoacetamide
CAS 380626-05-1C16H16N2OS
2-(Benzylamino)-N-(4-chlorophenyl)-2-thioxoacetamide chemical structure, C15H13ClN2OS, CAS 380626-11-9
2-(Benzylamino)-N-(4-chlorophenyl)-2-thioxoacetamide
CAS 380626-11-9C15H13ClN2OS
2-(Benzylamino)-N-(4-bromo-3-methylphenyl)-2-sulfanylideneacetamide chemical structure, C16H15BrN2OS, CAS 329079-16-5
2-(Benzylamino)-N-(4-bromo-3-methylphenyl)-2-sulfanylideneacetamide
CAS 329079-16-5C16H15BrN2OS
2-(Benzylamino)-N-[4-chloro-3-(trifluoromethyl)phenyl]-2-thioxoacetamide chemical structure, C16H12ClF3N2OS, CAS 329078-63-9
2-(Benzylamino)-N-[4-chloro-3-(trifluoromethyl)phenyl]-2-thioxoacetamide
CAS 329078-63-9C16H12ClF3N2OS
2-(Benzylamino)-N-(4-isopropylphenyl)-2-thioxoacetamide chemical structure, C18H20N2OS, CAS 303091-03-4
2-(Benzylamino)-N-(4-isopropylphenyl)-2-thioxoacetamide
CAS 303091-03-4C18H20N2OS
2-(Benzylamino)-N-(4-butylphenyl)-2-thioxoacetamide chemical structure, C19H22N2OS, CAS 329078-53-7
2-(Benzylamino)-N-(4-butylphenyl)-2-thioxoacetamide
CAS 329078-53-7C19H22N2OS
2-[(4-Chlorobenzyl)amino]-N-(2,5-difluorophenyl)-2-thioxoacetamide chemical structure, C15H11ClF2N2OS, CAS 882083-67-2
2-[(4-Chlorobenzyl)amino]-N-(2,5-difluorophenyl)-2-thioxoacetamide
CAS 882083-67-2C15H11ClF2N2OS
2-(Benzylamino)-N-(3,4-difluorophenyl)-2-thioxoacetamide chemical structure, C15H12F2N2OS, CAS 882078-93-5
2-(Benzylamino)-N-(3,4-difluorophenyl)-2-thioxoacetamide
CAS 882078-93-5C15H12F2N2OS
2-(Benzylamino)-N-(4-butan-2-ylphenyl)-2-sulfanylideneacetamide chemical structure, C19H22N2OS, CAS 329079-12-1
2-(Benzylamino)-N-(4-butan-2-ylphenyl)-2-sulfanylideneacetamide
CAS 329079-12-1C19H22N2OS
2-(Benzylamino)-2-thioxo-N-[4-(trifluoromethyl)phenyl]acetamide chemical structure, C16H13F3N2OS, CAS 939893-40-0
2-(Benzylamino)-2-thioxo-N-[4-(trifluoromethyl)phenyl]acetamide
CAS 939893-40-0C16H13F3N2OS