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Murcko scaffold

Ring system with 3 rings and 26 atoms

58 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
58
With full pages
8
Scaffold SMILES

O=C(Nc1ccccc1)C(=Cc1ccccc1)NC(=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)C(=Cc1ccccc1)NC(=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 58 chemicals

4-{[2-[(2-Methoxybenzoyl)amino]-3-(4-methoxyphenyl)acryloyl]amino}benzoic acid chemical structure, C25H22N2O6, CAS 354549-53-4
4-{[2-[(2-Methoxybenzoyl)amino]-3-(4-methoxyphenyl)acryloyl]amino}benzoic acid
CAS 354549-53-4C25H22N2O6
3-{[2-[(4-Bromobenzoyl)amino]-3-(4-methoxyphenyl)acryloyl]amino}benzoic acid chemical structure, C24H19BrN2O5, CAS 354549-69-2
3-{[2-[(4-Bromobenzoyl)amino]-3-(4-methoxyphenyl)acryloyl]amino}benzoic acid
CAS 354549-69-2C24H19BrN2O5
N-{2-{2-Nitro-4,5-dimethoxyphenyl}-1-[(4-iodoanilino)carbonyl]vinyl}benzamide chemical structure, C24H20IN3O6, CAS 342376-95-8
N-{2-{2-Nitro-4,5-dimethoxyphenyl}-1-[(4-iodoanilino)carbonyl]vinyl}benzamide
CAS 342376-95-8C24H20IN3O6
N-[(E)-3-Anilino-3-oxo-1-(4-propan-2-yloxyphenyl)prop-1-en-2-yl]benzamide chemical structure, C25H24N2O3, CAS 331259-50-8
N-[(E)-3-Anilino-3-oxo-1-(4-propan-2-yloxyphenyl)prop-1-en-2-yl]benzamide
CAS 331259-50-8C25H24N2O3
N-[1-(4-Bromophenyl)-3-(4-methoxyanilino)-3-oxoprop-1-en-2-yl]-2-chlorobenzamide chemical structure, C23H18BrClN2O3, CAS 5301-90-6
N-[1-(4-Bromophenyl)-3-(4-methoxyanilino)-3-oxoprop-1-en-2-yl]-2-chlorobenzamide
CAS 5301-90-6C23H18BrClN2O3
N-[(Z)-1-(4-Bromophenyl)-3-(4-methylanilino)-3-oxoprop-1-en-2-yl]benzamide chemical structure, C23H19BrN2O2, CAS 202063-93-2
N-[(Z)-1-(4-Bromophenyl)-3-(4-methylanilino)-3-oxoprop-1-en-2-yl]benzamide
CAS 202063-93-2C23H19BrN2O2
N-{2-(2-Ethoxyphenyl)-1-[(4-methoxyanilino)carbonyl]vinyl}benzamide chemical structure, C25H24N2O4, CAS 331271-65-9
N-{2-(2-Ethoxyphenyl)-1-[(4-methoxyanilino)carbonyl]vinyl}benzamide
CAS 331271-65-9C25H24N2O4
N-(1-(Anilinocarbonyl)-2-{3-nitrophenyl}vinyl)-3-bromobenzamide chemical structure, C22H16BrN3O4, CAS 423738-03-8
N-(1-(Anilinocarbonyl)-2-{3-nitrophenyl}vinyl)-3-bromobenzamide
CAS 423738-03-8C22H16BrN3O4
Ethyl 4-({2-[(4-methoxybenzoyl)amino]-3-phenylacryloyl}amino)benzoate chemical structure, C26H24N2O5, CAS 1189088-29-6
Ethyl 4-({2-[(4-methoxybenzoyl)amino]-3-phenylacryloyl}amino)benzoate
CAS 1189088-29-6C26H24N2O5
N-(1-[(4-Bromoanilino)carbonyl]-2-{2-nitro-4,5-dimethoxyphenyl}vinyl)benzamide chemical structure, C24H20BrN3O6, CAS 342591-85-9
N-(1-[(4-Bromoanilino)carbonyl]-2-{2-nitro-4,5-dimethoxyphenyl}vinyl)benzamide
CAS 342591-85-9C24H20BrN3O6
(2Z)-N-(4-Methoxyphenyl)-3-phenyl-2-(phenylcarbonylamino)prop-2-enamide chemical structure, C23H20N2O3, CAS 850869-25-9
(2Z)-N-(4-Methoxyphenyl)-3-phenyl-2-(phenylcarbonylamino)prop-2-enamide
CAS 850869-25-9C23H20N2O3
N-(2-Phenyl-1-(4-toluidinocarbonyl)vinyl)benzamide chemical structure, C23H20N2O2, CAS 72833-08-0
N-(2-Phenyl-1-(4-toluidinocarbonyl)vinyl)benzamide
CAS 72833-08-0C23H20N2O2
N-[(E)-3-(2-Hydroxyanilino)-3-oxo-1-phenylprop-1-en-2-yl]benzamide chemical structure, C22H18N2O3, CAS 384353-08-6
N-[(E)-3-(2-Hydroxyanilino)-3-oxo-1-phenylprop-1-en-2-yl]benzamide
CAS 384353-08-6C22H18N2O3
3-(4-Bromophenyl)-N-(4-methoxyphenyl)-2-(phenylformamido)prop-2-enamide chemical structure, C23H19BrN2O3, CAS 304000-99-5
3-(4-Bromophenyl)-N-(4-methoxyphenyl)-2-(phenylformamido)prop-2-enamide
CAS 304000-99-5C23H19BrN2O3
N-(1-((4-Bromoanilino)carbonyl)-2-phenylvinyl)-4-methylbenzamide chemical structure, C23H19BrN2O2, CAS 304002-33-3
N-(1-((4-Bromoanilino)carbonyl)-2-phenylvinyl)-4-methylbenzamide
CAS 304002-33-3C23H19BrN2O2
3-(4-Bromophenyl)-2-[(2-chlorophenyl)formamido]-N-(2-methoxyphenyl)prop-2-enamide chemical structure, C23H18BrClN2O3, CAS 304001-60-3
3-(4-Bromophenyl)-2-[(2-chlorophenyl)formamido]-N-(2-methoxyphenyl)prop-2-enamide
CAS 304001-60-3C23H18BrClN2O3
N-[(Z)-1-(4-Bromophenyl)-3-(2-methylanilino)-3-oxoprop-1-en-2-yl]-2-chlorobenzamide chemical structure, C23H18BrClN2O2, CAS 5302-47-6
N-[(Z)-1-(4-Bromophenyl)-3-(2-methylanilino)-3-oxoprop-1-en-2-yl]-2-chlorobenzamide
CAS 5302-47-6C23H18BrClN2O2
N-[(E)-3-Anilino-1-(3-bromophenyl)-3-oxoprop-1-en-2-yl]benzamide chemical structure, C22H17BrN2O2, CAS 5873-52-9
N-[(E)-3-Anilino-1-(3-bromophenyl)-3-oxoprop-1-en-2-yl]benzamide
CAS 5873-52-9C22H17BrN2O2
N-[(Z)-3-(4-Chloroanilino)-1-(2-methoxyphenyl)-3-oxoprop-1-en-2-yl]benzamide chemical structure, C23H19ClN2O3, CAS 302966-12-7
N-[(Z)-3-(4-Chloroanilino)-1-(2-methoxyphenyl)-3-oxoprop-1-en-2-yl]benzamide
CAS 302966-12-7C23H19ClN2O3
N-[1-{[(4-Bromophenyl)amino]carbonyl}-2-(2-methoxyphenyl)vinyl]benzamide chemical structure, C23H19BrN2O3, CAS 5306-61-6
N-[1-{[(4-Bromophenyl)amino]carbonyl}-2-(2-methoxyphenyl)vinyl]benzamide
CAS 5306-61-6C23H19BrN2O3
N-[1-{[(2-Methoxyphenyl)amino]carbonyl}-2-(3-nitrophenyl)vinyl]benzamide chemical structure, C23H19N3O5, CAS 5879-85-6
N-[1-{[(2-Methoxyphenyl)amino]carbonyl}-2-(3-nitrophenyl)vinyl]benzamide
CAS 5879-85-6C23H19N3O5
N-[(Z)-3-(4-Chloroanilino)-1-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl]benzamide chemical structure, C23H19ClN2O3, CAS 302930-51-4
N-[(Z)-3-(4-Chloroanilino)-1-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl]benzamide
CAS 302930-51-4C23H19ClN2O3
N-[(Z)-3-(4-Iodoanilino)-1-(2-methoxyphenyl)-3-oxoprop-1-en-2-yl]benzamide chemical structure, C23H19IN2O3, CAS 302966-13-8
N-[(Z)-3-(4-Iodoanilino)-1-(2-methoxyphenyl)-3-oxoprop-1-en-2-yl]benzamide
CAS 302966-13-8C23H19IN2O3
N-[(Z)-1-(3,4-Dimethoxyphenyl)-3-(2-methoxyanilino)-3-oxoprop-1-en-2-yl]benzamide chemical structure, C25H24N2O5, CAS 302930-34-3
N-[(Z)-1-(3,4-Dimethoxyphenyl)-3-(2-methoxyanilino)-3-oxoprop-1-en-2-yl]benzamide
CAS 302930-34-3C25H24N2O5