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Murcko scaffold

5-(Piperidin-4-yl)thiazole scaffold

32 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
32
With full pages
4
Scaffold SMILES

c1ncc(C2CCNCC2)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-(Piperidin-4-yl)thiazole page
Murcko scaffold c1ncc(C2CCNCC2)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

tert-Butyl 4-(1,3-thiazol-5-yl)piperidine-1-carboxylate chemical structure, C13H20N2O2S, CAS 301222-69-5
tert-Butyl 4-(1,3-thiazol-5-yl)piperidine-1-carboxylate
CAS 301222-69-5C13H20N2O2S
tert-Butyl 4-(2-amino-1,3-thiazol-5-yl)piperidine-1-carboxylate chemical structure, C13H21N3O2S, CAS 820231-21-8
tert-Butyl 4-(2-amino-1,3-thiazol-5-yl)piperidine-1-carboxylate
CAS 820231-21-8C13H21N3O2S
tert-Butyl 4-{2-[(trifluoroacetyl)amino]-1,3-thiazol-5-yl}piperidine-1-carboxylate chemical structure, C15H20F3N3O3S, CAS 820231-22-9
tert-Butyl 4-{2-[(trifluoroacetyl)amino]-1,3-thiazol-5-yl}piperidine-1-carboxylate
CAS 820231-22-9C15H20F3N3O3S
4-(4-Methyl-1,3-thiazol-5-yl)piperidine chemical structure, C9H14N2S, CAS 1367864-64-9
4-(4-Methyl-1,3-thiazol-5-yl)piperidine
CAS 1367864-64-9C9H14N2S
4-(2-Methyl-1,3-thiazol-5-yl)piperidine chemical structure, C9H14N2S, CAS 1368166-82-8
4-(2-Methyl-1,3-thiazol-5-yl)piperidine
CAS 1368166-82-8C9H14N2S
5-(Piperidin-4-yl)thiazole chemical structure, C8H12N2S, CAS 1367911-35-0
5-(Piperidin-4-yl)thiazole
CAS 1367911-35-0C8H12N2S
4-(2-Methoxy-1,3-thiazol-5-yl)piperidine chemical structure, C9H14N2OS, CAS 1536899-63-4
4-(2-Methoxy-1,3-thiazol-5-yl)piperidine
CAS 1536899-63-4C9H14N2OS
5-(Piperidin-4-yl)-1,3-thiazol-2-amine chemical structure, C8H13N3S, CAS 1256818-02-6
5-(Piperidin-4-yl)-1,3-thiazol-2-amine
CAS 1256818-02-6C8H13N3S
5-(1-Methylpiperidin-4-yl)-1,3-thiazol-2-amine chemical structure, C9H15N3S, CAS 1453212-71-9
5-(1-Methylpiperidin-4-yl)-1,3-thiazol-2-amine
CAS 1453212-71-9C9H15N3S
5-[1-[(2-Methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]-1,3-thiazole-4-carboxylic acid chemical structure, C14H20N2O4S, CAS 1449368-31-3
5-[1-[(2-Methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]-1,3-thiazole-4-carboxylic acid
CAS 1449368-31-3C14H20N2O4S
Methyl 5-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]-1,3-thiazole-4-carboxylate chemical structure, C15H22N2O4S, CAS 1449368-30-2
Methyl 5-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]-1,3-thiazole-4-carboxylate
CAS 1449368-30-2C15H22N2O4S
4-(4-Bromo-1,3-thiazol-5-yl)piperidin-4-ol chemical structure, C8H11BrN2OS, CAS 1700068-31-0
4-(4-Bromo-1,3-thiazol-5-yl)piperidin-4-ol
CAS 1700068-31-0C8H11BrN2OS
4-(2-Amino-1,3-thiazol-5-yl)-1-methylpiperidin-4-ol chemical structure, C9H15N3OS, CAS 1564560-84-4
4-(2-Amino-1,3-thiazol-5-yl)-1-methylpiperidin-4-ol
CAS 1564560-84-4C9H15N3OS
4-(2-Amino-1,3-thiazol-5-yl)-1-ethylpiperidin-4-ol chemical structure, C10H17N3OS, CAS 1564725-94-5
4-(2-Amino-1,3-thiazol-5-yl)-1-ethylpiperidin-4-ol
CAS 1564725-94-5C10H17N3OS
4-(2-Amino-1,3-thiazol-5-yl)piperidin-4-ol chemical structure, C8H13N3OS, CAS 1566448-06-3
4-(2-Amino-1,3-thiazol-5-yl)piperidin-4-ol
CAS 1566448-06-3C8H13N3OS
4-(2-Chloro-1,3-thiazol-5-yl)piperidine chemical structure, C8H11ClN2S, CAS 1895179-55-1
4-(2-Chloro-1,3-thiazol-5-yl)piperidine
CAS 1895179-55-1C8H11ClN2S
4-(1,3-Thiazol-5-yl)piperidine dihydrochloride chemical structure, C8H14Cl2N2S, CAS 2094408-93-0
4-(1,3-Thiazol-5-yl)piperidine dihydrochloride
CAS 2094408-93-0C8H14Cl2N2S
tert-Butyl4-(2-bromo-1,3-thiazol-5-yl)piperidine-1-carboxylate chemical structure, C13H19BrN2O2S, CAS 2380302-37-2
tert-Butyl4-(2-bromo-1,3-thiazol-5-yl)piperidine-1-carboxylate
CAS 2380302-37-2C13H19BrN2O2S
4-(4-Methyl-1,3-thiazol-5-yl)piperidine dihydrochloride chemical structure, C9H16Cl2N2S, CAS 2490418-77-2
4-(4-Methyl-1,3-thiazol-5-yl)piperidine dihydrochloride
CAS 2490418-77-2C9H16Cl2N2S
4-Methyl-5-(2-methylpiperidin-4-yl)-1,3-thiazole-2-carboxylic acid chemical structure, C11H16N2O2S, CAS 2137639-76-8
4-Methyl-5-(2-methylpiperidin-4-yl)-1,3-thiazole-2-carboxylic acid
CAS 2137639-76-8C11H16N2O2S
4-(2-Amino-1,3-thiazol-5-yl)-2,2,6,6-tetramethylpiperidin-4-ol chemical structure, C12H21N3OS, CAS 2137792-14-2
4-(2-Amino-1,3-thiazol-5-yl)-2,2,6,6-tetramethylpiperidin-4-ol
CAS 2137792-14-2C12H21N3OS
tert-Butyl 4-(2-amino-1,3-thiazol-5-yl)-4-hydroxypiperidine-1-carboxylate chemical structure, C13H21N3O3S, CAS 2138252-64-7
tert-Butyl 4-(2-amino-1,3-thiazol-5-yl)-4-hydroxypiperidine-1-carboxylate
CAS 2138252-64-7C13H21N3O3S
tert-Butyl 4-(2-amino-1,3-thiazol-5-yl)-4-hydroxy-2,2,6,6-tetramethylpiperidine-1-carboxylate chemical structure, C17H29N3O3S, CAS 2137785-70-5
tert-Butyl 4-(2-amino-1,3-thiazol-5-yl)-4-hydroxy-2,2,6,6-tetramethylpiperidine-1-carboxylate
CAS 2137785-70-5C17H29N3O3S
N,N,4-trimethyl-5-(piperidin-4-yl)-1,3-thiazol-2-amine chemical structure, C11H19N3S, CAS 2229565-90-4
N,N,4-trimethyl-5-(piperidin-4-yl)-1,3-thiazol-2-amine
CAS 2229565-90-4C11H19N3S