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Murcko scaffold

N-[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl]-N-phenylbenzenesulfonamide scaffold

40 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
31
Chemicals
40
With full pages
1
Scaffold SMILES

O=C(CN(c1ccccc1)S(=O)(=O)c1ccccc1)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl]-N-phenylbenzenesulfonamide page
Murcko scaffold O=C(CN(c1ccccc1)S(=O)(=O)c1ccccc1)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

N-[2-[4-(3-Chlorophenyl)piperazin-1-yl]-2-oxoethyl]-N-(2,4-dimethoxyphenyl)-4-methylbenzenesulfonamide chemical structure, C27H30ClN3O5S, CAS 693805-31-1
N-[2-[4-(3-Chlorophenyl)piperazin-1-yl]-2-oxoethyl]-N-(2,4-dimethoxyphenyl)-4-methylbenzenesulfonamide
CAS 693805-31-1C27H30ClN3O5S
N-[2-[4-(5-Chloro-2-methylphenyl)-1-piperazinyl]-2-oxoethyl]-N-(4-methylphenyl)benzenesulfonamide chemical structure, C26H28ClN3O3S, CAS 667877-46-5
N-[2-[4-(5-Chloro-2-methylphenyl)-1-piperazinyl]-2-oxoethyl]-N-(4-methylphenyl)benzenesulfonamide
CAS 667877-46-5C26H28ClN3O3S
N-[2-[4-(3-Chlorophenyl)piperazin-1-yl]-2-oxoethyl]-4-fluoro-N-(4-methylphenyl)benzenesulfonamide chemical structure, C25H25ClFN3O3S, CAS 663160-70-1
N-[2-[4-(3-Chlorophenyl)piperazin-1-yl]-2-oxoethyl]-4-fluoro-N-(4-methylphenyl)benzenesulfonamide
CAS 663160-70-1C25H25ClFN3O3S
N-(2-Ethoxyphenyl)-4-methyl-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide chemical structure, C27H31N3O4S, CAS 361199-67-9
N-(2-Ethoxyphenyl)-4-methyl-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide
CAS 361199-67-9C27H31N3O4S
N-(3,4-Dichlorophenyl)-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide chemical structure, C24H23Cl2N3O3S, CAS 361199-74-8
N-(3,4-Dichlorophenyl)-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide
CAS 361199-74-8C24H23Cl2N3O3S
N-(2,3-Dimethylphenyl)-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide chemical structure, C26H29N3O3S, CAS 431981-18-9
N-(2,3-Dimethylphenyl)-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide
CAS 431981-18-9C26H29N3O3S
N-(2-Ethoxyphenyl)-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl]benzenesulfonamide chemical structure, C27H31N3O5S, CAS 354786-69-9
N-(2-Ethoxyphenyl)-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl]benzenesulfonamide
CAS 354786-69-9C27H31N3O5S
N-(2-Fluorophenyl)-4-methyl-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide chemical structure, C25H26FN3O3S, CAS 354787-02-3
N-(2-Fluorophenyl)-4-methyl-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide
CAS 354787-02-3C25H26FN3O3S
N-(2,4-Dimethylphenyl)-4-methyl-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide chemical structure, C27H31N3O3S, CAS 425665-37-8
N-(2,4-Dimethylphenyl)-4-methyl-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide
CAS 425665-37-8C27H31N3O3S
N-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl]-4-methyl-N-(2-methylphenyl)benzenesulfonamide chemical structure, C27H31N3O4S, CAS 428459-23-8
N-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]-2-oxoethyl]-4-methyl-N-(2-methylphenyl)benzenesulfonamide
CAS 428459-23-8C27H31N3O4S
N-(2,5-Dimethylphenyl)-4-methyl-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide chemical structure, C27H31N3O3S, CAS 428447-50-1
N-(2,5-Dimethylphenyl)-4-methyl-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide
CAS 428447-50-1C27H31N3O3S
N-[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl]-N-(4-propan-2-ylphenyl)benzenesulfonamide chemical structure, C27H31N3O3S, CAS 398520-96-2
N-[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl]-N-(4-propan-2-ylphenyl)benzenesulfonamide
CAS 398520-96-2C27H31N3O3S
N-[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl]-N-phenylbenzenesulfonamide chemical structure, C24H25N3O3S, CAS 428494-10-4
N-[2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl]-N-phenylbenzenesulfonamide
CAS 428494-10-4C24H25N3O3S
N-(3-Chloro-2-methylphenyl)-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide chemical structure, C25H26ClN3O3S, CAS 428497-85-2
N-(3-Chloro-2-methylphenyl)-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide
CAS 428497-85-2C25H26ClN3O3S
N-(5-Chloro-2-methylphenyl)-4-methyl-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide chemical structure, C26H28ClN3O3S, CAS 501913-10-6
N-(5-Chloro-2-methylphenyl)-4-methyl-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide
CAS 501913-10-6C26H28ClN3O3S
N-(2,5-Dimethylphenyl)-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide chemical structure, C26H29N3O3S, CAS 428495-28-7
N-(2,5-Dimethylphenyl)-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide
CAS 428495-28-7C26H29N3O3S
4-Methyl-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]-N-(4-propan-2-ylphenyl)benzenesulfonamide chemical structure, C28H33N3O3S, CAS 501913-50-4
4-Methyl-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]-N-(4-propan-2-ylphenyl)benzenesulfonamide
CAS 501913-50-4C28H33N3O3S
4-Methyl-N-(4-methylphenyl)-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide chemical structure, C26H29N3O3S, CAS 428502-02-7
4-Methyl-N-(4-methylphenyl)-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide
CAS 428502-02-7C26H29N3O3S
N-(4-Ethoxyphenyl)-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl]-4-methylsulfanylbenzenesulfonamide chemical structure, C28H33N3O5S2, CAS 332035-11-7
N-(4-Ethoxyphenyl)-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl]-4-methylsulfanylbenzenesulfonamide
CAS 332035-11-7C28H33N3O5S2
N-(2,4-Dimethoxyphenyl)-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl]benzenesulfonamide chemical structure, C27H31N3O6S, CAS 6069-94-9
N-(2,4-Dimethoxyphenyl)-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl]benzenesulfonamide
CAS 6069-94-9C27H31N3O6S
N-(4-Bromophenyl)-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl]benzenesulfonamide chemical structure, C25H26BrN3O4S, CAS 6075-39-4
N-(4-Bromophenyl)-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl]benzenesulfonamide
CAS 6075-39-4C25H26BrN3O4S
N-(4-Ethoxyphenyl)-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide chemical structure, C26H29N3O4S, CAS 331725-43-0
N-(4-Ethoxyphenyl)-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide
CAS 331725-43-0C26H29N3O4S
N-(2,4-Dimethylphenyl)-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxo-ethyl]benzenesulfonamide chemical structure, C27H31N3O4S, CAS 6079-49-8
N-(2,4-Dimethylphenyl)-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxo-ethyl]benzenesulfonamide
CAS 6079-49-8C27H31N3O4S
4-Methyl-N-(2-methylphenyl)-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide chemical structure, C26H29N3O3S, CAS 312288-27-0
4-Methyl-N-(2-methylphenyl)-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide
CAS 312288-27-0C26H29N3O3S