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Murcko scaffold

N-Pyrazin-2-ylbenzenesulfonamide scaffold

66 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
66
With full pages
10
Scaffold SMILES

O=S(=O)(Nc1cnccn1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Pyrazin-2-ylbenzenesulfonamide page
Murcko scaffold O=S(=O)(Nc1cnccn1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 66 chemicals

Sulfapyrazine chemical structure, C10H10N4O2S, CAS 116-44-9
Sulfapyrazine
CAS 116-44-9C10H10N4O2S
Sulfalene chemical structure, C11H12N4O3S, CAS 152-47-6
Sulfalene
CAS 152-47-6C11H12N4O3S
Acetyl sulfamethoxypyrazine chemical structure, C13H14N4O4S, CAS 3590-05-4
Acetyl sulfamethoxypyrazine
CAS 3590-05-4C13H14N4O4S
Sulfaclozine chemical structure, C10H9ClN4O2S, CAS 102-65-8
Sulfaclozine
CAS 102-65-8C10H9ClN4O2S
Sulfachlorpyrazine chemical structure, C10H9ClN4O2S, CAS 1672-91-9
Sulfachlorpyrazine
CAS 1672-91-9C10H9ClN4O2S
Sulfalene N-methylglucamine salt chemical structure, C18H29N5O8S, CAS 62907-78-2
Sulfalene N-methylglucamine salt
CAS 62907-78-2C18H29N5O8S
3-[(4-Acetamidophenyl)sulfonylamino]pyrazine-2-carboxamide chemical structure, C13H13N5O4S, CAS 5414-68-6
3-[(4-Acetamidophenyl)sulfonylamino]pyrazine-2-carboxamide
CAS 5414-68-6C13H13N5O4S
4-Amino-N-(3,6-dimethylpyrazin-2-yl)benzenesulfonamide chemical structure, C12H14N4O2S, CAS 5433-89-6
4-Amino-N-(3,6-dimethylpyrazin-2-yl)benzenesulfonamide
CAS 5433-89-6C12H14N4O2S
N-[4-(Pyrazin-2-ylsulfamoyl)phenyl]acetamide chemical structure, C12H12N4O3S, CAS 5433-91-0
N-[4-(Pyrazin-2-ylsulfamoyl)phenyl]acetamide
CAS 5433-91-0C12H12N4O3S
2-Sulfanilamido-5,6-dimethylpyrazine chemical structure, C12H14N4O2S, CAS 6298-34-6
2-Sulfanilamido-5,6-dimethylpyrazine
CAS 6298-34-6C12H14N4O2S
2-Sulfanilamido-6-methylpyrazine chemical structure, C11H12N4O2S, CAS 6298-35-7
2-Sulfanilamido-6-methylpyrazine
CAS 6298-35-7C11H12N4O2S
N-Pyrazin-2-ylbenzenesulfonamide chemical structure, C10H9N3O2S, CAS 7471-20-7
N-Pyrazin-2-ylbenzenesulfonamide
CAS 7471-20-7C10H9N3O2S
N1-(3-Chloropyrazinyl)-sulfanilamide chemical structure, C10H9ClN4O2S, CAS 14423-79-1
N1-(3-Chloropyrazinyl)-sulfanilamide
CAS 14423-79-1C10H9ClN4O2S
N-(3,5-Dimethylpyrazin-2-yl)benzenesulfonamide chemical structure, C12H13N3O2S, CAS 239081-12-0
N-(3,5-Dimethylpyrazin-2-yl)benzenesulfonamide
CAS 239081-12-0C12H13N3O2S
N-(3-Methoxy-2-pyrazinyl)-4-(3-[3,3,3-trifluoro-1-(pentafluoroethyl)-2-(trifluoromethyl)-1-propenyl]-2-thioureido)benzenesulfonamide chemical structure, C18H12F11N5O3S2, CAS 306766-78-9
N-(3-Methoxy-2-pyrazinyl)-4-(3-[3,3,3-trifluoro-1-(pentafluoroethyl)-2-(trifluoromethyl)-1-propenyl]-2-thioureido)benzenesulfonamide
CAS 306766-78-9C18H12F11N5O3S2
Acetamide, N-(4-(((3-chloro-2-pyrazinyl)amino)sulfonyl)phenyl)- chemical structure, C12H11ClN4O3S, CAS 40837-23-8
Acetamide, N-(4-(((3-chloro-2-pyrazinyl)amino)sulfonyl)phenyl)-
CAS 40837-23-8C12H11ClN4O3S
4-Methyl-N-(pyrazin-2-yl)benzenesulfonamide chemical structure, C11H11N3O2S, CAS 712301-24-1
4-Methyl-N-(pyrazin-2-yl)benzenesulfonamide
CAS 712301-24-1C11H11N3O2S
4-Isothiocyanato-N-(3-methoxypyrazin-2-yl)benzenesulfonamide chemical structure, C12H10N4O3S2, CAS 887833-54-7
4-Isothiocyanato-N-(3-methoxypyrazin-2-yl)benzenesulfonamide
CAS 887833-54-7C12H10N4O3S2
Acetamide,N-[4-[[(3-methoxypyrazinyl)amino]sulfonyl]phenyl]- chemical structure, C13H14N4O4S, CAS 655-78-7
Acetamide,N-[4-[[(3-methoxypyrazinyl)amino]sulfonyl]phenyl]-
CAS 655-78-7C13H14N4O4S
2,3-Dichloro-N-(3,5-dichloro-2-pyrazinyl)benzenesulphonamide chemical structure, C10H5Cl4N3O2S, CAS 566203-96-1
2,3-Dichloro-N-(3,5-dichloro-2-pyrazinyl)benzenesulphonamide
CAS 566203-96-1C10H5Cl4N3O2S
N-(3-Methoxy-5-methyl-2-pyrazinyl)-2-iodobenzenesulphonamide chemical structure, C12H12IN3O3S, CAS 173253-52-6
N-(3-Methoxy-5-methyl-2-pyrazinyl)-2-iodobenzenesulphonamide
CAS 173253-52-6C12H12IN3O3S
N-(5-Bromo-3-methoxy-2-pyrazinyl)4-chlorobenzenesulphonamide chemical structure, C11H9BrClN3O3S, CAS 566203-68-7
N-(5-Bromo-3-methoxy-2-pyrazinyl)4-chlorobenzenesulphonamide
CAS 566203-68-7C11H9BrClN3O3S
2,3-Dichloro-N-(3-methoxypyrazin-2-yl)benzenesulfonamide chemical structure, C11H9Cl2N3O3S, CAS 566203-88-1
2,3-Dichloro-N-(3-methoxypyrazin-2-yl)benzenesulfonamide
CAS 566203-88-1C11H9Cl2N3O3S
2,3-Dichloro-N-(5-chloro-3-methoxypyrazinyl)benzenesulfonamide chemical structure, C11H8Cl3N3O3S, CAS 566203-62-1
2,3-Dichloro-N-(5-chloro-3-methoxypyrazinyl)benzenesulfonamide
CAS 566203-62-1C11H8Cl3N3O3S