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Murcko scaffold

N-Pyrazin-2-ylbenzenesulfonamide scaffold

66 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
66
With full pages
10
Scaffold SMILES

O=S(=O)(Nc1cnccn1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Pyrazin-2-ylbenzenesulfonamide page
Murcko scaffold O=S(=O)(Nc1cnccn1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 66 of 66 chemicals

N-(6-Amino-5-bromo-3-methoxypyrazin-2-yl)-2,3-dichloro-benzenesulfonamide chemical structure, C11H9BrCl2N4O3S, CAS 931093-33-3
N-(6-Amino-5-bromo-3-methoxypyrazin-2-yl)-2,3-dichloro-benzenesulfonamide
CAS 931093-33-3C11H9BrCl2N4O3S
4-Amino-2-fluoro-N-2-pyrazinylbenzenesulfonamide chemical structure, C10H9FN4O2S, CAS 1285432-18-9
4-Amino-2-fluoro-N-2-pyrazinylbenzenesulfonamide
CAS 1285432-18-9C10H9FN4O2S
N-(5-Bromopyrazin-2-yl)-3-chlorobenzenesulfonamide chemical structure, C10H7BrClN3O2S, CAS 1394709-62-6
N-(5-Bromopyrazin-2-yl)-3-chlorobenzenesulfonamide
CAS 1394709-62-6C10H7BrClN3O2S
N-(5-Bromopyrazin-2-yl)-2-chlorobenzenesulfonamide chemical structure, C10H7BrClN3O2S, CAS 1394691-91-8
N-(5-Bromopyrazin-2-yl)-2-chlorobenzenesulfonamide
CAS 1394691-91-8C10H7BrClN3O2S
Sodium sulfachloropyrazine monohydrate chemical structure, C10H10ClN4NaO3S, CAS 1392129-96-2
Sodium sulfachloropyrazine monohydrate
CAS 1392129-96-2C10H10ClN4NaO3S
4-Amino-3-fluoro-N-2-pyrazinylbenzenesulfonamide chemical structure, C10H9FN4O2S, CAS 1555508-84-3
4-Amino-3-fluoro-N-2-pyrazinylbenzenesulfonamide
CAS 1555508-84-3C10H9FN4O2S
N-(5-Bromo-pyrazin-2-yl)-N-cyanomethyl-4-methyl-benzenesulfonamide chemical structure, C13H11BrN4O2S, CAS 767342-44-9
N-(5-Bromo-pyrazin-2-yl)-N-cyanomethyl-4-methyl-benzenesulfonamide
CAS 767342-44-9C13H11BrN4O2S
N-(6-Chloropyrazin-2-yl)benzenesulfonamide chemical structure, C10H8ClN3O2S, CAS 887310-35-2
N-(6-Chloropyrazin-2-yl)benzenesulfonamide
CAS 887310-35-2C10H8ClN3O2S
N-(3-Methoxypyrazin-2-yl)-4-nitrobenzenesulfonamide chemical structure, C11H10N4O5S, CAS 94625-43-1
N-(3-Methoxypyrazin-2-yl)-4-nitrobenzenesulfonamide
CAS 94625-43-1C11H10N4O5S
Sulfachloropyrazine-13C6 chemical structure, C10H9ClN4O2S, CAS 1416711-61-9
Sulfachloropyrazine-13C6
CAS 1416711-61-9C10H9ClN4O2S
(3-(5-(4-Acetamidophenylsulfonamido)-6-methoxypyrazin-2-yl)propyl)carbamate tert-Butyl Ester chemical structure, C21H29N5O6S, CAS 1621083-39-3
(3-(5-(4-Acetamidophenylsulfonamido)-6-methoxypyrazin-2-yl)propyl)carbamate tert-Butyl Ester
CAS 1621083-39-3C21H29N5O6S
tert-Butyl(3-(5-(4-Aminophenylsulfonamido)-6-methoxypyrazin-2-yl)propyl)carbamate chemical structure, C19H27N5O5S, CAS 1621083-43-9
tert-Butyl(3-(5-(4-Aminophenylsulfonamido)-6-methoxypyrazin-2-yl)propyl)carbamate
CAS 1621083-43-9C19H27N5O5S
4-Amino-N-(5-chloropyrazin-2-yl)benzenesulfonamide hydrochloride chemical structure, C10H10Cl2N4O2S, CAS 2034430-99-2
4-Amino-N-(5-chloropyrazin-2-yl)benzenesulfonamide hydrochloride
CAS 2034430-99-2C10H10Cl2N4O2S
N-(3-Methoxypyrazin-2-yl)-N-((4-nitrophenyl)sulfonyl)acetamide chemical structure, C13H12N4O6S, CAS 96097-52-8
N-(3-Methoxypyrazin-2-yl)-N-((4-nitrophenyl)sulfonyl)acetamide
CAS 96097-52-8C13H12N4O6S
2-Chloro-N-(5-chloro-6-methoxy-2-pyrazinyl)benzenesulfonamide chemical structure, C11H9Cl2N3O3S, CAS 2254226-02-1
2-Chloro-N-(5-chloro-6-methoxy-2-pyrazinyl)benzenesulfonamide
CAS 2254226-02-1C11H9Cl2N3O3S
N-(3-Aminopropyl)-N-(6-chloropyrazin-2-yl)-2-nitrobenzene-1-sulfonamide chemical structure, C13H14ClN5O4S, CAS 2138114-94-8
N-(3-Aminopropyl)-N-(6-chloropyrazin-2-yl)-2-nitrobenzene-1-sulfonamide
CAS 2138114-94-8C13H14ClN5O4S
N-(3-Aminopropyl)-N-(6-chloropyrazin-2-yl)-4-nitrobenzene-1-sulfonamide chemical structure, C13H14ClN5O4S, CAS 2138121-09-0
N-(3-Aminopropyl)-N-(6-chloropyrazin-2-yl)-4-nitrobenzene-1-sulfonamide
CAS 2138121-09-0C13H14ClN5O4S
tert-Butyl N-{4-[(3-chloropyrazin-2-yl)sulfamoyl]phenyl}carbamate chemical structure, C15H17ClN4O4S, CAS 2680668-02-2
tert-Butyl N-{4-[(3-chloropyrazin-2-yl)sulfamoyl]phenyl}carbamate
CAS 2680668-02-2C15H17ClN4O4S