CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 17 atoms

21 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
21
With full pages
9
Scaffold SMILES

O=C(Nc1cc(=O)[nH]c(=O)[nH]1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cc(=O)[nH]c(=O)[nH]1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-3-nitrobenzamide chemical structure, C13H12N4O5, CAS 309951-42-6
N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-3-nitrobenzamide
CAS 309951-42-6C13H12N4O5
N-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3-methoxybenzamide chemical structure, C14H15N3O4, CAS 438614-09-6
N-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3-methoxybenzamide
CAS 438614-09-6C14H15N3O4
2-Chloro-N-(1,3-dimethyl-2,6-dioxopyrimidin-4-yl)-4-nitrobenzamide chemical structure, C13H11ClN4O5, CAS 321533-29-3
2-Chloro-N-(1,3-dimethyl-2,6-dioxopyrimidin-4-yl)-4-nitrobenzamide
CAS 321533-29-3C13H11ClN4O5
5-Chloro-N-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-2-nitrobenzamide chemical structure, C13H11ClN4O5, CAS 445288-94-8
5-Chloro-N-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-2-nitrobenzamide
CAS 445288-94-8C13H11ClN4O5
N-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,4,5-triethoxybenzamide chemical structure, C19H25N3O6, CAS 353774-13-7
N-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,4,5-triethoxybenzamide
CAS 353774-13-7C19H25N3O6
N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-3,5-dimethoxybenzamide chemical structure, C15H17N3O5, CAS 352693-78-8
N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-3,5-dimethoxybenzamide
CAS 352693-78-8C15H17N3O5
N-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,4,5-trimethoxybenzamide chemical structure, C16H19N3O6, CAS 631868-68-3
N-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,4,5-trimethoxybenzamide
CAS 631868-68-3C16H19N3O6
N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-2-ethoxybenzamide chemical structure, C15H17N3O4, CAS 445021-03-4
N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-2-ethoxybenzamide
CAS 445021-03-4C15H17N3O4
N-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-2-methyl-3-nitrobenzamide chemical structure, C14H14N4O5, CAS 631868-76-3
N-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-2-methyl-3-nitrobenzamide
CAS 631868-76-3C14H14N4O5
5-Bromo-2-chloro-N-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)benzamide chemical structure, C13H11BrClN3O3, CAS 631868-77-4
5-Bromo-2-chloro-N-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)benzamide
CAS 631868-77-4C13H11BrClN3O3
N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-3,5-dimethylbenzamide chemical structure, C15H17N3O3, CAS 633296-36-3
N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-3,5-dimethylbenzamide
CAS 633296-36-3C15H17N3O3
3-Chloro-N-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)benzamide chemical structure, C13H12ClN3O3, CAS 633296-42-1
3-Chloro-N-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)benzamide
CAS 633296-42-1C13H12ClN3O3
N-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,4-dimethylbenzamide chemical structure, C15H17N3O3, CAS 633296-49-8
N-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,4-dimethylbenzamide
CAS 633296-49-8C15H17N3O3
N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-4-ethoxybenzamide chemical structure, C15H17N3O4, CAS 424819-10-3
N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-4-ethoxybenzamide
CAS 424819-10-3C15H17N3O4
N-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)benzamide chemical structure, C13H13N3O3, CAS 633296-52-3
N-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)benzamide
CAS 633296-52-3C13H13N3O3
4-Chloro-N-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)benzamide chemical structure, C13H12ClN3O3, CAS 633296-54-5
4-Chloro-N-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)benzamide
CAS 633296-54-5C13H12ClN3O3
N-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-2-iodobenzamide chemical structure, C13H12IN3O3, CAS 633296-60-3
N-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-2-iodobenzamide
CAS 633296-60-3C13H12IN3O3
N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-4-(dimethylsulfamoyl)benzamide chemical structure, C15H18N4O5S, CAS 633296-82-9
N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-4-(dimethylsulfamoyl)benzamide
CAS 633296-82-9C15H18N4O5S
N-(2,6-Dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3-nitrobenzamide chemical structure, C11H8N4O5, CAS 294891-16-0
N-(2,6-Dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3-nitrobenzamide
CAS 294891-16-0C11H8N4O5
2-Chloro-N-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-5-nitrobenzamide chemical structure, C11H7ClN4O5, CAS 868216-27-7
2-Chloro-N-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-5-nitrobenzamide
CAS 868216-27-7C11H7ClN4O5
N-(3-Methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)benzamide chemical structure, C12H11N3O3, CAS 712286-96-9
N-(3-Methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)benzamide
CAS 712286-96-9C12H11N3O3