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Murcko scaffold

Ring system with 5 rings and 35 atoms

10 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
35
Chemicals
10
With full pages
3
Scaffold SMILES

O=C1CCCC(CCn2cc(C(=O)Nc3ccccc3)c(-c3ccccc3)c2-c2ccccc2)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCC(CCn2cc(C(=O)Nc3ccccc3)c(-c3ccccc3)c2-c2ccccc2)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Atorvastatin lactone chemical structure, C33H33FN2O4, CAS 125995-03-1
Atorvastatin lactone
CAS 125995-03-1C33H33FN2O4
p-Hydroxyatorvastatin lactone chemical structure, C33H33FN2O5, CAS 163217-70-7
p-Hydroxyatorvastatin lactone
CAS 163217-70-7C33H33FN2O5
o-Hydroxyatorvastatin lactone chemical structure, C33H33FN2O5, CAS 163217-74-1
o-Hydroxyatorvastatin lactone
CAS 163217-74-1C33H33FN2O5
4-Hydroxy atorvastatin lactone-d5 chemical structure, C33H33FN2O5, CAS 265989-49-9
4-Hydroxy atorvastatin lactone-d5
CAS 265989-49-9C33H33FN2O5
2-Hydroxy atorvastatin lactone-d5 chemical structure, C33H33FN2O5, CAS 265989-50-2
2-Hydroxy atorvastatin lactone-d5
CAS 265989-50-2C33H33FN2O5
Atorvastatin IMpurity H chemical structure, C33H33FN2O4, CAS 160449-60-5
Atorvastatin IMpurity H
CAS 160449-60-5C33H33FN2O4
Atorvastatin-d5 lactone chemical structure, C33H33FN2O4, CAS 1217749-86-4
Atorvastatin-d5 lactone
CAS 1217749-86-4C33H33FN2O4
5-(4-Fluorophenyl)-1-[2-[(2S,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-4-(2,3,4,5,6-pentadeuteriophenyl)-N-phenyl-2-propan-2-ylpyrrole-3-carboxamide chemical structure, C33H33FN2O4, CAS 265989-48-8
5-(4-Fluorophenyl)-1-[2-[(2S,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-4-(2,3,4,5,6-pentadeuteriophenyl)-N-phenyl-2-propan-2-ylpyrrole-3-carboxamide
CAS 265989-48-8C33H33FN2O4
4-tert-Butyldimethylsilyl Atorvastatin Lactone chemical structure, C39H47FN2O4Si, CAS 842162-99-6
4-tert-Butyldimethylsilyl Atorvastatin Lactone
CAS 842162-99-6C39H47FN2O4Si
1-[2-[4-[tert-Butyl(dimethyl)silyl]oxy-6-oxooxan-2-yl]ethyl]-5-(4-fluorophenyl)-N,4-diphenyl-2-propan-2-ylpyrrole-3-carboxamide chemical structure, C39H47FN2O4Si
1-[2-[4-[tert-Butyl(dimethyl)silyl]oxy-6-oxooxan-2-yl]ethyl]-5-(4-fluorophenyl)-N,4-diphenyl-2-propan-2-ylpyrrole-3-carboxamide
C39H47FN2O4Si