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Murcko scaffold

Ring system with 3 rings and 23 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
7
With full pages
3
Scaffold SMILES

O=C(C=CC=CC=CC1C=CC(=O)C2OC12)NC1=CCCC1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=CC=CC=CC1C=CC(=O)C2OC12)NC1=CCCC1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

Manumycin chemical structure, C31H38N2O7, CAS 52665-74-4
Manumycin
CAS 52665-74-4C31H38N2O7
2,4,6-Decatrienamide, N-(5-hydroxy-5-(7-((2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino)-7-oxo-1,3,5-heptatrienyl)-2-oxo-7-oxabicyclo(4.1.0)hept-3-en-3-yl)-9-methyl- chemical structure, C29H32N2O7, CAS 87695-80-5
2,4,6-Decatrienamide, N-(5-hydroxy-5-(7-((2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino)-7-oxo-1,3,5-heptatrienyl)-2-oxo-7-oxabicyclo(4.1.0)hept-3-en-3-yl)-9-methyl-
CAS 87695-80-5C29H32N2O7
Manumycin B chemical structure, C28H34N2O7, CAS 139023-58-8
Manumycin B
CAS 139023-58-8C28H34N2O7
Manumycin G chemical structure, C28H30N2O7, CAS 156250-44-1
Manumycin G
CAS 156250-44-1C28H30N2O7
Manumycin E chemical structure, C30H34N2O7, CAS 156250-43-0
Manumycin E
CAS 156250-43-0C30H34N2O7
EI-1511-3 chemical structure, C27H30N2O7, CAS 176661-65-7
EI-1511-3
CAS 176661-65-7C27H30N2O7
EI-1625-2 chemical structure, C27H32N2O7, CAS 176661-67-9
EI-1625-2
CAS 176661-67-9C27H32N2O7