Murcko scaffold
3-Phenyl-2-(thiophen-2-yl)-2,3-dihydroquinazolin-4(1H)-one scaffold
6 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 22
- Chemicals
- 6
- With full pages
- 2
Scaffold SMILES
O=C1c2ccccc2NC(c2cccs2)N1c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 6 of 6 chemicals
3-Phenyl-2-(thiophen-2-yl)-2,3-dihydroquinazolin-4(1H)-one
CAS 361984-43-2C18H14N2OS
3-(2-Methoxy-phenyl)-2-(3-methyl-thiophen-2-yl)-2,3-dihydro-1H-quinazolin-4-one
CAS 444789-88-2C20H18N2O2S
2-(3-Methylthiophen-2-yl)-3-(o-tolyl)-2,3-dihydroquinazolin-4(1H)-one
CAS 440111-61-5C20H18N2OS
Retro-2 S-enantiomer
CAS 1510796-68-5C19H16N2OS
3-(4-Ethoxyphenyl)-6-iodo-2-(2-thienyl)-2,3-dihydro-4(1H)-quinazolinone
CAS 352701-49-6C20H17IN2O2S
2-(5-Methylthiophen-2-yl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one
CAS 1429192-00-6C19H16N2OS