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Murcko scaffold

Ring system with 3 rings and 26 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
15
With full pages
8
Scaffold SMILES

O=C(NCCc1ccccc1)C1CCN(S(=O)(=O)c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCCc1ccccc1)C1CCN(S(=O)(=O)c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

(S)-3-Phenyl-2-(1-tosylpiperidine-4-carboxamido)propanoic acid chemical structure, C22H26N2O5S, CAS 956777-58-5
(S)-3-Phenyl-2-(1-tosylpiperidine-4-carboxamido)propanoic acid
CAS 956777-58-5C22H26N2O5S
1-[(4-Bromophenyl)sulfonyl]-N-(2-phenylethyl)piperidine-4-carboxamide chemical structure, C20H23BrN2O3S, CAS 433971-54-1
1-[(4-Bromophenyl)sulfonyl]-N-(2-phenylethyl)piperidine-4-carboxamide
CAS 433971-54-1C20H23BrN2O3S
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-(4-methylphenyl)sulfonylpiperidine-4-carboxamide chemical structure, C23H30N2O5S, CAS 433947-87-6
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-(4-methylphenyl)sulfonylpiperidine-4-carboxamide
CAS 433947-87-6C23H30N2O5S
1-(Toluene-4-sulfonyl)-piperidine-4-carboxylic acid phenethyl-amide chemical structure, C21H26N2O3S, CAS 433699-34-4
1-(Toluene-4-sulfonyl)-piperidine-4-carboxylic acid phenethyl-amide
CAS 433699-34-4C21H26N2O3S
1-(4-Bromophenyl)sulfonyl-N-[2-(4-methoxyphenyl)ethyl]piperidine-4-carboxamide chemical structure, C21H25BrN2O4S, CAS 433971-69-8
1-(4-Bromophenyl)sulfonyl-N-[2-(4-methoxyphenyl)ethyl]piperidine-4-carboxamide
CAS 433971-69-8C21H25BrN2O4S
N-[2-(4-Methoxyphenyl)ethyl]-1-(2,4,6-trimethylphenyl)sulfonylpiperidine-4-carboxamide chemical structure, C24H32N2O4S, CAS 695176-89-7
N-[2-(4-Methoxyphenyl)ethyl]-1-(2,4,6-trimethylphenyl)sulfonylpiperidine-4-carboxamide
CAS 695176-89-7C24H32N2O4S
1-[(4-Fluorobenzene)sulfonyl]-N-(2-phenylethyl)piperidine-4-carboxamide chemical structure, C20H23FN2O3S, CAS 591226-92-5
1-[(4-Fluorobenzene)sulfonyl]-N-(2-phenylethyl)piperidine-4-carboxamide
CAS 591226-92-5C20H23FN2O3S
1-(4-Fluorophenyl)sulfonyl-N-[2-(4-methoxyphenyl)ethyl]piperidine-4-carboxamide chemical structure, C21H25FN2O4S, CAS 591238-66-3
1-(4-Fluorophenyl)sulfonyl-N-[2-(4-methoxyphenyl)ethyl]piperidine-4-carboxamide
CAS 591238-66-3C21H25FN2O4S
N-[2-(4-Methoxyphenyl)ethyl]-1-(4-methylphenyl)sulfonylpiperidine-4-carboxamide chemical structure, C22H28N2O4S, CAS 433965-91-4
N-[2-(4-Methoxyphenyl)ethyl]-1-(4-methylphenyl)sulfonylpiperidine-4-carboxamide
CAS 433965-91-4C22H28N2O4S
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-(4-fluorophenyl)sulfonylpiperidine-4-carboxamide chemical structure, C22H27FN2O5S, CAS 591238-17-4
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-(4-fluorophenyl)sulfonylpiperidine-4-carboxamide
CAS 591238-17-4C22H27FN2O5S
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-[(3,4-dimethoxyphenyl)sulfonyl]piperidine-4-carboxamide chemical structure, C24H32N2O7S, CAS 433690-49-4
N-[2-(3,4-Dimethoxyphenyl)ethyl]-1-[(3,4-dimethoxyphenyl)sulfonyl]piperidine-4-carboxamide
CAS 433690-49-4C24H32N2O7S
1-[(3,4-Dimethoxyphenyl)sulfonyl]-N-[2-(4-methoxyphenyl)ethyl]-4-piperidinecarboxamide chemical structure, C23H30N2O6S, CAS 593244-77-0
1-[(3,4-Dimethoxyphenyl)sulfonyl]-N-[2-(4-methoxyphenyl)ethyl]-4-piperidinecarboxamide
CAS 593244-77-0C23H30N2O6S
1-[(3,4-Dimethoxyphenyl)sulfonyl]-N-(2-phenylethyl)piperidine-4-carboxamide chemical structure, C22H28N2O5S, CAS 591239-59-7
1-[(3,4-Dimethoxyphenyl)sulfonyl]-N-(2-phenylethyl)piperidine-4-carboxamide
CAS 591239-59-7C22H28N2O5S
N-[2-(2,4-Dichlorophenyl)ethyl]-1-[(4-fluorophenyl)sulfonyl]piperidine-4-carboxamide chemical structure, C20H21Cl2FN2O3S, CAS 903852-45-9
N-[2-(2,4-Dichlorophenyl)ethyl]-1-[(4-fluorophenyl)sulfonyl]piperidine-4-carboxamide
CAS 903852-45-9C20H21Cl2FN2O3S
N-[2-(4-Fluorophenyl)ethyl]-1-[(2-fluorophenyl)sulfonyl]-4-piperidinecarboxamide chemical structure, C20H22F2N2O3S, CAS 1180558-28-4
N-[2-(4-Fluorophenyl)ethyl]-1-[(2-fluorophenyl)sulfonyl]-4-piperidinecarboxamide
CAS 1180558-28-4C20H22F2N2O3S