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Murcko scaffold

3-(4-Benzylpiperazin-1-yl)-N-phenylpropanamide scaffold

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
20
With full pages
6
Scaffold SMILES

O=C(CCN1CCN(Cc2ccccc2)CC1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-(4-Benzylpiperazin-1-yl)-N-phenylpropanamide page
Murcko scaffold O=C(CCN1CCN(Cc2ccccc2)CC1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

3-(4-Benzylpiperazin-1-yl)-N-(2,5-dimethoxyphenyl)propanamide chemical structure, C22H29N3O3, CAS 428834-84-8
3-(4-Benzylpiperazin-1-yl)-N-(2,5-dimethoxyphenyl)propanamide
CAS 428834-84-8C22H29N3O3
3-(4-Benzylpiperazin-1-yl)-N-phenylpropanamide chemical structure, C20H25N3O, CAS 100222-06-8
3-(4-Benzylpiperazin-1-yl)-N-phenylpropanamide
CAS 100222-06-8C20H25N3O
3-(4-Benzylpiperazin-1-yl)-N-(4-fluorophenyl)propanamide chemical structure, C20H24FN3O, CAS 159671-84-8
3-(4-Benzylpiperazin-1-yl)-N-(4-fluorophenyl)propanamide
CAS 159671-84-8C20H24FN3O
3-(4-Benzylpiperazin-1-yl)-N-(2-fluorophenyl)propanamide chemical structure, C20H24FN3O, CAS 100222-05-7
3-(4-Benzylpiperazin-1-yl)-N-(2-fluorophenyl)propanamide
CAS 100222-05-7C20H24FN3O
3-(4-Benzylpiperazin-1-yl)-N-(3-fluorophenyl)propanamide chemical structure, C20H24FN3O, CAS 428844-41-1
3-(4-Benzylpiperazin-1-yl)-N-(3-fluorophenyl)propanamide
CAS 428844-41-1C20H24FN3O
3-(4-Benzylpiperazin-1-yl)-N-(3-methylphenyl)propanamide chemical structure, C21H27N3O, CAS 461397-68-2
3-(4-Benzylpiperazin-1-yl)-N-(3-methylphenyl)propanamide
CAS 461397-68-2C21H27N3O
3-(4-Benzylpiperazin-1-yl)-N-(4-methylphenyl)propanamide chemical structure, C21H27N3O, CAS 191168-69-1
3-(4-Benzylpiperazin-1-yl)-N-(4-methylphenyl)propanamide
CAS 191168-69-1C21H27N3O
3-(4-Benzylpiperazin-1-yl)-N-(2-methylphenyl)propanamide chemical structure, C21H27N3O, CAS 429623-88-1
3-(4-Benzylpiperazin-1-yl)-N-(2-methylphenyl)propanamide
CAS 429623-88-1C21H27N3O
3-(4-Benzylpiperazin-1-yl)-N-(3,5-dimethoxyphenyl)propanamide chemical structure, C22H29N3O3, CAS 428829-39-4
3-(4-Benzylpiperazin-1-yl)-N-(3,5-dimethoxyphenyl)propanamide
CAS 428829-39-4C22H29N3O3
3-(4-Benzylpiperazin-1-yl)-N-(3,4-dimethylphenyl)propanamide chemical structure, C22H29N3O, CAS 519005-01-7
3-(4-Benzylpiperazin-1-yl)-N-(3,4-dimethylphenyl)propanamide
CAS 519005-01-7C22H29N3O
3-(4-Benzylpiperazin-1-yl)-N-(4-methoxyphenyl)propanamide chemical structure, C21H27N3O2, CAS 191168-71-5
3-(4-Benzylpiperazin-1-yl)-N-(4-methoxyphenyl)propanamide
CAS 191168-71-5C21H27N3O2
3-(4-Benzylpiperazin-1-yl)-N-(4-chlorophenyl)propanamide chemical structure, C20H24ClN3O, CAS 428846-01-9
3-(4-Benzylpiperazin-1-yl)-N-(4-chlorophenyl)propanamide
CAS 428846-01-9C20H24ClN3O
3-(4-Benzylpiperazin-1-yl)-N-(4-bromo-3-methylphenyl)propanamide chemical structure, C21H26BrN3O, CAS 428852-22-6
3-(4-Benzylpiperazin-1-yl)-N-(4-bromo-3-methylphenyl)propanamide
CAS 428852-22-6C21H26BrN3O
3-(4-Benzylpiperazin-1-yl)-N-(2-chlorophenyl)propanamide chemical structure, C20H24ClN3O, CAS 100222-04-6
3-(4-Benzylpiperazin-1-yl)-N-(2-chlorophenyl)propanamide
CAS 100222-04-6C20H24ClN3O
3-(4-Benzylpiperazin-1-yl)-N-(2,5-dimethylphenyl)propanamide chemical structure, C22H29N3O, CAS 428848-74-2
3-(4-Benzylpiperazin-1-yl)-N-(2,5-dimethylphenyl)propanamide
CAS 428848-74-2C22H29N3O
3-(4-Benzylpiperazin-1-yl)-N-(3-chloro-2-methylphenyl)propanamide chemical structure, C21H26ClN3O, CAS 429621-70-5
3-(4-Benzylpiperazin-1-yl)-N-(3-chloro-2-methylphenyl)propanamide
CAS 429621-70-5C21H26ClN3O
3-(4-Benzylpiperazin-1-yl)-N-(4-bromophenyl)propanamide chemical structure, C20H24BrN3O, CAS 428504-68-1
3-(4-Benzylpiperazin-1-yl)-N-(4-bromophenyl)propanamide
CAS 428504-68-1C20H24BrN3O
3-(4-Benzylpiperazin-1-yl)-N-(2,4-dimethoxyphenyl)propanamide chemical structure, C22H29N3O3, CAS 428839-76-3
3-(4-Benzylpiperazin-1-yl)-N-(2,4-dimethoxyphenyl)propanamide
CAS 428839-76-3C22H29N3O3
3-(4-Benzylpiperazin-1-yl)-N-(3-methoxyphenyl)propanamide chemical structure, C21H27N3O2, CAS 428849-14-3
3-(4-Benzylpiperazin-1-yl)-N-(3-methoxyphenyl)propanamide
CAS 428849-14-3C21H27N3O2
3-(4-Benzylpiperazin-1-yl)-N-(4-sulfamoylphenyl)propanamide chemical structure, C20H26N4O3S, CAS 839717-54-3
3-(4-Benzylpiperazin-1-yl)-N-(4-sulfamoylphenyl)propanamide
CAS 839717-54-3C20H26N4O3S