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Murcko scaffold

2-Phenyl-1,2-benzisothiazol-3-(2H)-one scaffold

31 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
31
With full pages
15
Scaffold SMILES

O=c1c2ccccc2sn1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenyl-1,2-benzisothiazol-3-(2H)-one page
Murcko scaffold O=c1c2ccccc2sn1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

2-Phenyl-1,2-benzisothiazol-3-(2H)-one chemical structure, C13H9NOS, CAS 2527-03-9
2-Phenyl-1,2-benzisothiazol-3-(2H)-one
CAS 2527-03-9C13H9NOS
RefChem:381356 chemical structure, C14H11NOS, CAS 4299-23-4
RefChem:381356
CAS 4299-23-4C14H11NOS
2-(4-Methylphenyl)-2,3-dihydro-1,2-benzothiazol-3-one chemical structure, C14H11NOS, CAS 2514-30-9
2-(4-Methylphenyl)-2,3-dihydro-1,2-benzothiazol-3-one
CAS 2514-30-9C14H11NOS
6-Fluoro-2-(2-methylphenyl)-1,2-benzothiazol-3-one chemical structure, C14H10FNOS, CAS 727664-79-1
6-Fluoro-2-(2-methylphenyl)-1,2-benzothiazol-3-one
CAS 727664-79-1C14H10FNOS
2-(2,5-Dimethylphenyl)-6-fluoro-1,2-benzothiazol-3-one chemical structure, C15H12FNOS, CAS 727664-91-7
2-(2,5-Dimethylphenyl)-6-fluoro-1,2-benzothiazol-3-one
CAS 727664-91-7C15H12FNOS
N,N-Diethyl-3-(3-oxo-2,3-dihydro-1,2-benzothiazol-2-yl)benzene-1-sulfonamide chemical structure, C17H18N2O3S2, CAS 565165-15-3
N,N-Diethyl-3-(3-oxo-2,3-dihydro-1,2-benzothiazol-2-yl)benzene-1-sulfonamide
CAS 565165-15-3C17H18N2O3S2
Ethyl 4-(3-oxo-1,2-benzisothiazol-2(3H)-yl)benzoate chemical structure, C16H13NO3S, CAS 78471-81-5
Ethyl 4-(3-oxo-1,2-benzisothiazol-2(3H)-yl)benzoate
CAS 78471-81-5C16H13NO3S
2-(3-Chloro-4-fluorophenyl)-2,3-dihydro-1,2-benzothiazol-3-one chemical structure, C13H7ClFNOS, CAS 565166-89-4
2-(3-Chloro-4-fluorophenyl)-2,3-dihydro-1,2-benzothiazol-3-one
CAS 565166-89-4C13H7ClFNOS
N,N-Dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamide chemical structure, C15H14N2O3S2, CAS 716375-92-7
N,N-Dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamide
CAS 716375-92-7C15H14N2O3S2
2-(4-Methoxyphenyl)-1,2-benzothiazol-3-one chemical structure, C14H11NO2S, CAS 2514-33-2
2-(4-Methoxyphenyl)-1,2-benzothiazol-3-one
CAS 2514-33-2C14H11NO2S
2-(4-Chlorophenyl)-1,2-benzothiazol-3-one chemical structure, C13H8ClNOS, CAS 2620-91-9
2-(4-Chlorophenyl)-1,2-benzothiazol-3-one
CAS 2620-91-9C13H8ClNOS
Benzonitrile, 4-(3-oxo-1,2-benzisothiazol-2(3H)-yl)- chemical structure, C14H8N2OS, CAS 88112-07-6
Benzonitrile, 4-(3-oxo-1,2-benzisothiazol-2(3H)-yl)-
CAS 88112-07-6C14H8N2OS
1,2-Benzisothiazol-3(2H)-one, 2-(2-bromo-4-methylphenyl)- chemical structure, C14H10BrNOS, CAS 88312-81-6
1,2-Benzisothiazol-3(2H)-one, 2-(2-bromo-4-methylphenyl)-
CAS 88312-81-6C14H10BrNOS
4-(3-Oxo-1,2-benzisothiazol-2(3H)-yl)benzoic acid chemical structure, C14H9NO3S, CAS 78471-84-8
4-(3-Oxo-1,2-benzisothiazol-2(3H)-yl)benzoic acid
CAS 78471-84-8C14H9NO3S
2-(3-Oxo-1,2-benzothiazol-2-yl)benzonitrile chemical structure, C14H8N2OS, CAS 78471-88-2
2-(3-Oxo-1,2-benzothiazol-2-yl)benzonitrile
CAS 78471-88-2C14H8N2OS
3-(3-Oxo-1,2-benzothiazol-2-yl)benzonitrile chemical structure, C14H8N2OS, CAS 78471-89-3
3-(3-Oxo-1,2-benzothiazol-2-yl)benzonitrile
CAS 78471-89-3C14H8N2OS
SARS-CoV-2-IN-69 chemical structure, C15H11NO3S, CAS 78471-90-6
SARS-CoV-2-IN-69
CAS 78471-90-6C15H11NO3S
2-(4-Nitrophenyl)-1,2-benzisothiazol-3(2H)-one chemical structure, C13H8N2O3S, CAS 4322-98-9
2-(4-Nitrophenyl)-1,2-benzisothiazol-3(2H)-one
CAS 4322-98-9C13H8N2O3S
N[(4MeOCO)Ph]benzoisothiazolone chemical structure, C15H11NO3S, CAS 4322-93-4
N[(4MeOCO)Ph]benzoisothiazolone
CAS 4322-93-4C15H11NO3S
2-[4-(3-Oxo-1,2-benzothiazol-2(3H)-yl)phenyl]acetamide chemical structure, C15H12N2O2S, CAS 102486-56-6
2-[4-(3-Oxo-1,2-benzothiazol-2(3H)-yl)phenyl]acetamide
CAS 102486-56-6C15H12N2O2S
2-[4-(3-Oxo-1,2-benzothiazol-2(3H)-yl)phenyl]propanamide chemical structure, C16H14N2O2S, CAS 102486-57-7
2-[4-(3-Oxo-1,2-benzothiazol-2(3H)-yl)phenyl]propanamide
CAS 102486-57-7C16H14N2O2S
2-[4-(3-Oxo-1,2-benzothiazol-2(3H)-yl)phenyl]butanamide chemical structure, C17H16N2O2S, CAS 102486-61-3
2-[4-(3-Oxo-1,2-benzothiazol-2(3H)-yl)phenyl]butanamide
CAS 102486-61-3C17H16N2O2S
N,N-Dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzamide chemical structure, C16H14N2O2S, CAS 1177148-36-5
N,N-Dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzamide
CAS 1177148-36-5C16H14N2O2S
5-Fluoro-2-phenyl-1,2-benzothiazol-3-one chemical structure, C13H8FNOS, CAS 1306638-12-9
5-Fluoro-2-phenyl-1,2-benzothiazol-3-one
CAS 1306638-12-9C13H8FNOS