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Murcko scaffold

Ring system with 3 rings and 20 atoms

20 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 20
Chemicals: 20
With full pages: 4

Scaffold SMILES

O=C(Nc1ccccc1)c1n[nH]c(=O)c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(Nc1ccccc1)c1n[nH]c(=O)c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

N-(4-Ethylphenyl)-4-oxo-3H-phthalazine-1-carboxamide chemical structure, C17H15N3O2, CAS 442855-43-8

N-(4-Ethylphenyl)-4-oxo-3H-phthalazine-1-carboxamide

CAS 442855-43-8C₁₇H₁₅N₃O₂

3-Methyl-4-oxo-N-[3-(trifluoromethyl)phenyl]phthalazine-1-carboxamide chemical structure, C17H12F3N3O2, CAS 697244-76-1

3-Methyl-4-oxo-N-[3-(trifluoromethyl)phenyl]phthalazine-1-carboxamide

CAS 697244-76-1C₁₇H₁₂F₃N₃O₂

N-(2-Methoxyphenyl)-3-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide chemical structure, C17H15N3O3, CAS 708223-16-9

N-(2-Methoxyphenyl)-3-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide

CAS 708223-16-9C₁₇H₁₅N₃O₃

N-(4-Fluorophenyl)-3-methyl-4-oxophthalazine-1-carboxamide chemical structure, C16H12FN3O2, CAS 697244-75-0

N-(4-Fluorophenyl)-3-methyl-4-oxophthalazine-1-carboxamide

CAS 697244-75-0C₁₆H₁₂FN₃O₂

N-(4-Methoxyphenyl)-3-methyl-4-oxophthalazine-1-carboxamide chemical structure, C17H15N3O3, CAS 708247-82-9

N-(4-Methoxyphenyl)-3-methyl-4-oxophthalazine-1-carboxamide

CAS 708247-82-9C₁₇H₁₅N₃O₃

N,3-dimethyl-4-oxo-N-phenylphthalazine-1-carboxamide chemical structure, C17H15N3O2, CAS 727676-16-6

N,3-dimethyl-4-oxo-N-phenylphthalazine-1-carboxamide

CAS 727676-16-6C₁₇H₁₅N₃O₂

N-(4-Bromo-3-methylphenyl)-4-oxo-3H-phthalazine-1-carboxamide chemical structure, C16H12BrN3O2, CAS 757215-06-8

N-(4-Bromo-3-methylphenyl)-4-oxo-3H-phthalazine-1-carboxamide

CAS 757215-06-8C₁₆H₁₂BrN₃O₂

N-(3-Acetamidophenyl)-3-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide chemical structure, C18H16N4O3, CAS 797002-98-3

N-(3-Acetamidophenyl)-3-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide

CAS 797002-98-3C₁₈H₁₆N₄O₃

3-Methyl-N-[3-(methylsulfanyl)phenyl]-4-oxo-3,4-dihydrophthalazine-1-carboxamide chemical structure, C17H15N3O2S, CAS 796980-19-3

3-Methyl-N-[3-(methylsulfanyl)phenyl]-4-oxo-3,4-dihydrophthalazine-1-carboxamide

CAS 796980-19-3C₁₇H₁₅N₃O₂S

N-(2,4-Dimethoxyphenyl)-3-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide chemical structure, C18H17N3O4, CAS 1003548-50-2

N-(2,4-Dimethoxyphenyl)-3-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide

CAS 1003548-50-2C₁₈H₁₇N₃O₄

N-(3-Chloro-4-fluorophenyl)-3-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide chemical structure, C16H11ClFN3O2, CAS 797001-65-1

N-(3-Chloro-4-fluorophenyl)-3-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide

CAS 797001-65-1C₁₆H₁₁ClFN₃O₂

N-(4-Carbamoylphenyl)-3-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide chemical structure, C17H14N4O3, CAS 848065-82-7

N-(4-Carbamoylphenyl)-3-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide

CAS 848065-82-7C₁₇H₁₄N₄O₃

N-(4-Acetamidophenyl)-3-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide chemical structure, C18H16N4O3, CAS 727701-20-4

N-(4-Acetamidophenyl)-3-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide

CAS 727701-20-4C₁₈H₁₆N₄O₃

N-(2,6-Dimethylphenyl)-3-methyl-4-oxophthalazine-1-carboxamide chemical structure, C18H17N3O2, CAS 850703-31-0

N-(2,6-Dimethylphenyl)-3-methyl-4-oxophthalazine-1-carboxamide

CAS 850703-31-0C₁₈H₁₇N₃O₂

N-[3-(Dimethylsulfamoyl)phenyl]-4-oxo-3H-phthalazine-1-carboxamide chemical structure, C17H16N4O4S, CAS 792955-66-9

N-[3-(Dimethylsulfamoyl)phenyl]-4-oxo-3H-phthalazine-1-carboxamide

CAS 792955-66-9C₁₇H₁₆N₄O₄S

3-Methyl-4-oxo-N-(3,4,5-trimethoxyphenyl)-3,4-dihydrophthalazine-1-carboxamide chemical structure, C19H19N3O5, CAS 876707-40-3

3-Methyl-4-oxo-N-(3,4,5-trimethoxyphenyl)-3,4-dihydrophthalazine-1-carboxamide

CAS 876707-40-3C₁₉H₁₉N₃O₅

N-(2,4-Dichlorophenyl)-3-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide chemical structure, C16H11Cl2N3O2, CAS 1203041-43-3

N-(2,4-Dichlorophenyl)-3-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide

CAS 1203041-43-3C₁₆H₁₁Cl₂N₃O₂

N-(4-{[3-(2-Methylpropyl)-4-oxo-3,4-dihydrophthalazine-1-carbonyl]amino}benzoyl)glycine chemical structure, C22H22N4O5, CAS 1797131-65-7

N-(4-{[3-(2-Methylpropyl)-4-oxo-3,4-dihydrophthalazine-1-carbonyl]amino}benzoyl)glycine

CAS 1797131-65-7C₂₂H₂₂N₄O₅

N-(3,4-Dimethoxyphenyl)-4-oxo-3-pentyl-3,4-dihydrophthalazine-1-carboxamide chemical structure, C22H25N3O4, CAS 1327395-89-0

N-(3,4-Dimethoxyphenyl)-4-oxo-3-pentyl-3,4-dihydrophthalazine-1-carboxamide

CAS 1327395-89-0C₂₂H₂₅N₃O₄

3-Methyl-4-oxo-N-(3,4,5-trifluorophenyl)-3,4-dihydrophthalazine-1-carboxamide chemical structure, C16H10F3N3O2, CAS 1630862-40-6

3-Methyl-4-oxo-N-(3,4,5-trifluorophenyl)-3,4-dihydrophthalazine-1-carboxamide

CAS 1630862-40-6C₁₆H₁₀F₃N₃O₂