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Murcko scaffold

Ring system with 3 rings and 16 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
11
With full pages
3
Scaffold SMILES

O=c1ccnc2nc(-c3ccccc3)[nH]n12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccnc2nc(-c3ccccc3)[nH]n12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

5-Methyl-2-phenyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C12H10N4O, CAS 36372-09-5
5-Methyl-2-phenyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 36372-09-5C12H10N4O
2-Phenyl-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7-ol chemical structure, C14H14N4O, CAS 158872-98-1
2-Phenyl-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7-ol
CAS 158872-98-1C14H14N4O
Methyl (7-oxo-2-phenyl-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-5-yl)acetate chemical structure, C14H12N4O3, CAS 919742-21-5
Methyl (7-oxo-2-phenyl-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-5-yl)acetate
CAS 919742-21-5C14H12N4O3
Ethyl 3-(5-methyl-7-oxo-2-phenyl-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propanoate chemical structure, C17H18N4O3, CAS 919720-71-1
Ethyl 3-(5-methyl-7-oxo-2-phenyl-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propanoate
CAS 919720-71-1C17H18N4O3
5-Methyl-6-(3-methylbutyl)-2-phenyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C17H20N4O, CAS 919725-16-9
5-Methyl-6-(3-methylbutyl)-2-phenyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 919725-16-9C17H20N4O
6-Ethyl-5-methyl-2-(3,4,5-trimethoxyphenyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-ol chemical structure, C17H20N4O4, CAS 924870-93-9
6-Ethyl-5-methyl-2-(3,4,5-trimethoxyphenyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-ol
CAS 924870-93-9C17H20N4O4
3-(5-Methyl-7-oxo-2-phenyl-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propanoic acid chemical structure, C15H14N4O3, CAS 1030457-30-7
3-(5-Methyl-7-oxo-2-phenyl-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propanoic acid
CAS 1030457-30-7C15H14N4O3
5-(Chloromethyl)-2-phenyl-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one chemical structure, C12H9ClN4O, CAS 1227417-79-9
5-(Chloromethyl)-2-phenyl-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
CAS 1227417-79-9C12H9ClN4O
5-(Hydroxymethyl)-2-phenyl-3H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one chemical structure, C12H10N4O2, CAS 1290045-90-7
5-(Hydroxymethyl)-2-phenyl-3H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
CAS 1290045-90-7C12H10N4O2
5-(Chloromethyl)-2-(2-methylphenyl)[1,2,4]triazolo[1,5-A]pyrimidin-7(4H)-one chemical structure, C13H11ClN4O, CAS 2281831-51-2
5-(Chloromethyl)-2-(2-methylphenyl)[1,2,4]triazolo[1,5-A]pyrimidin-7(4H)-one
CAS 2281831-51-2C13H11ClN4O
6-Chloro-2-(4-fluorophenyl)-(1,2,4)triazolo(1,5-a)pyrimidin-7-ol chemical structure, C11H6ClFN4O, CAS 2411221-66-2
6-Chloro-2-(4-fluorophenyl)-(1,2,4)triazolo(1,5-a)pyrimidin-7-ol
CAS 2411221-66-2C11H6ClFN4O