Murcko scaffold
Phenyl pyrazine-2-carboxylate scaffold
11 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 15
- Chemicals
- 11
- With full pages
- 4
Scaffold SMILES
O=C(Oc1ccccc1)c1cnccn1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 11 of 11 chemicals
Pyrazinecarboxylic acid, p-nitrophenyl ester
CAS 20088-23-7C11H7N3O4
Pyrazinecarboxylic acid, 4-methylphenyl ester
CAS 132172-96-4C12H10N2O2
Pyrazinecarboxylic acid, 4-(1,1-dimethylethyl)phenyl ester
CAS 132172-94-2C15H16N2O2
Pyrazinecarboxylic acid, pentafluorophenyl ester
CAS 139244-50-1C11H3F5N2O2
(4-Bromo-2-chloro-6-methylphenyl) pyrazine-2-carboxylate
CAS 736187-15-8C12H8BrClN2O2
(2,3,6-Trimethylphenyl) 5-methylpyrazine-2-carboxylate
CAS 565201-18-5C15H16N2O2
(2,3-Dichlorophenyl) 5-methylpyrazine-2-carboxylate
CAS 565202-51-9C12H8Cl2N2O2
(4-Cyanophenyl) pyrazine-2-carboxylate
CAS 727717-44-4C12H7N3O2
Phenyl 3-aminopyrazine-2-carboxylate
CAS 256414-85-4C11H9N3O2
Phenyl 5-methylpyrazine-2-carboxylate
CAS 1348196-43-9C12H10N2O2
Phenyl pyrazine-2-carboxylate
CAS 184592-91-4C11H8N2O2