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Murcko scaffold

Ring system with 4 rings and 20 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
6
With full pages
1
Scaffold SMILES

O=C1CC(c2ccccc2)Oc2c1ccc1c2CCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC(c2ccccc2)Oc2c1ccc1c2CCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

2,3,8,9-Tetrahydro-5-hydroxy-2-(4-hydroxyphenyl)-8,9,9-trimethyl-4H-furo[2,3-h]-1-benzopyran-4-one chemical structure, C20H20O5, CAS 50868-49-0
2,3,8,9-Tetrahydro-5-hydroxy-2-(4-hydroxyphenyl)-8,9,9-trimethyl-4H-furo[2,3-h]-1-benzopyran-4-one
CAS 50868-49-0C20H20O5
Phellodensin D chemical structure, C20H20O6, CAS 531503-84-1
Phellodensin D
CAS 531503-84-1C20H20O6
2',4'-Dihydroxy-2''-(1-hydroxy-1-methylethyl)dihydrofuro(2,3-h)flavanone chemical structure, C20H20O6, CAS 376590-18-0
2',4'-Dihydroxy-2''-(1-hydroxy-1-methylethyl)dihydrofuro(2,3-h)flavanone
CAS 376590-18-0C20H20O6
Phellodensin A chemical structure, C20H18O6, CAS 612086-81-4
Phellodensin A
CAS 612086-81-4C20H18O6
Emoroidenone chemical structure, C21H20O4, CAS 169532-89-2
Emoroidenone
CAS 169532-89-2C21H20O4
4H-Furo(2,3-h)-1-benzopyran-4-one, 2,3,8,9-tetrahydro-3,5-dihydroxy-8-(1-hydroxy-1-methylethyl)-2-(4-hydroxyphenyl)-, (2R,3R)- chemical structure, C20H20O7, CAS 612086-83-6
4H-Furo(2,3-h)-1-benzopyran-4-one, 2,3,8,9-tetrahydro-3,5-dihydroxy-8-(1-hydroxy-1-methylethyl)-2-(4-hydroxyphenyl)-, (2R,3R)-
CAS 612086-83-6C20H20O7